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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Cerebral Hemorrhage; Pre-Eclampsia; Proteinuria; Heart Failure; Hypertension; Ventricular Dysfunction, Left
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cannabinoid CB1 receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Obsessive-Compulsive Disorder; Fibromyalgia; Marijuana Abuse; Muscle Spasticity; Neuralgia; Obesity; Suicidal Ideation; Diabetic Neuropathies; Parkinson Disease; Nausea; Neoplasms; Postoperative Nausea and Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glaucoma, Open-Angle; Ocular Hypertension; Cardiovascular Diseases; Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: BILIARY; PERFUSION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cannabinoid CB1 receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Diabetes Mellitus, Type 2; Essential Tremor; Multiple Sclerosis; Schizophrenia; Substance-Related Disorders; Alcohol Drinking; Amyotrophic Lateral Sclerosis; Arthritis, Psoriatic; Chronic Pain; Dementia; HIV Infections; Irritable Bowel Syndrome; Marijuana Abuse; Migraine with Aura; Migraine without Aura; Neuralgia; Opioid-Related Disorders; Pain; Sleep Apnea, Obstructive; Stress Disorders, Post-Traumatic; Torticollis; Tourette Syndrome; Trichotillomania; Anorexia Nervosa; Osteoarthritis; Osteoarthritis, Knee; Anorexia; Nausea; Neoplasms; Postoperative Nausea and Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: NASAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anemia; Anemia, Sickle Cell; Arthritis, Rheumatoid; Aspergillosis; Atherosclerosis; Carcinoma, Non-Small-Cell Lung; Cardiovascular Diseases; Chronic Pain; Cocaine-Related Disorders; Colitis, Ulcerative; Communicable Diseases; Cough; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus, Type 2; Endometriosis; Fatigue; Gastrointestinal Stromal Tumors; HIV Infections; Heart Failure; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Hernia, Inguinal; Infections; Influenza, Human; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Low Back Pain; Lymphoma, Non-Hodgkin; Malaria; Melanoma; Mesothelioma; Mitochondrial Diseases; Multiple Myeloma; Muscular Atrophy, Spinal; Myositis Ossificans; Nausea; Neck Pain; Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Osteoporosis, Postmenopausal; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Renal Insufficiency; Respiratory Syncytial Virus Infections; Sepsis; Severe Acute Respiratory Syndrome; Skin Diseases; Substance-Related Disorders; Suicidal Ideation; Tobacco Use Disorder; Tuberculosis; Aggression; Bipolar Disorder; Borderline Personality Disorder; Breast Neoplasms; Cataract; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Fractures, Multiple; Hypotension; Ischemic Stroke; Obsessive-Compulsive Disorder; Seizures; Stress Disorders, Post-Traumatic; Subarachnoid Hemorrhage; Tonsillitis; Tuberculosis, Pulmonary; Urogenital Neoplasms; Anxiety; Brain Injuries; Breech Presentation; Delirium; Dementia; Depressive Disorder; Fluoride Poisoning; Fractures, Bone; Hemorrhage; Hypertension; Infertility; Liver Cirrhosis; Multiple Sclerosis, Relapsing-Remitting; Pain; Postoperative Nausea and Vomiting; Respiratory Insufficiency; Schizophrenia; Shock, Septic; Wounds and Injuries; Amnesia; Epilepsy; Status Epilepticus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arthralgia; Cardiovascular Diseases; Myalgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Brain Neoplasms; Ovarian Cysts; Reperfusion Injury; Atrial Fibrillation; Pain; Sinusitis; Coronary Disease; Intracranial Aneurysm; Shock, Septic; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Chorioamnionitis; Cleft Palate; Infections; Kidney Calculi; Pyelonephritis; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: MUSCULOSKELETAL; OTHER; RHEUMATOLOGY
THERAPEUTIC INDICATION: Kidney Calculi; Renal Colic; Paget Disease, Extramammary; Periodontitis; Bursitis; Inflammation; Low Back Pain; Migraine Disorders; Osteoarthritis, Knee; Postoperative Nausea and Vomiting; Sprains and Strains; Tendinopathy; Wounds and Injuries; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Dysmenorrhea; Myalgia; Osteoarthritis; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Status Asthmaticus; Pulmonary Disease, Chronic Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: D2-like dopamine receptor inverse agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Delirium; Conduct Disorder; Psychotic Disorders; Schizophrenia; Tourette Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Stress Disorders, Post-Traumatic; Alcohol Drinking; Alcoholism; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Marijuana Abuse; Schizotypal Personality Disorder; Smoking Cessation; Stroke; Substance-Related Disorders; Tobacco Use Disorder; Trigeminal Neuralgia; Alzheimer Disease; Delirium; Tourette Syndrome; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Uremia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cryptosporidiosis; Tuberculosis, Pulmonary; Crohn Disease; Mycobacterium avium-intracellulare Infection; Tuberculosis; Tuberculosis, Multidrug-Resistant; Leprosy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; HIV Infections; Mitochondrial Diseases; Low Back Pain; Periodontitis; Pain; Pharyngitis; Arthralgia; Eye Diseases; Miosis; Myalgia; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Polyuria; Urinary Incontinence
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Retinoid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-sensitive sodium channel blocker
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lice Infestations; Lyme Disease; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Plasminogen inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Cerebral Hemorrhage; Epistaxis; Intervertebral Disc Degeneration; Osteoarthritis, Knee; Shock, Septic; Subarachnoid Hemorrhage; Urinary Bladder Neoplasms; Anemia; Angioedemas, Hereditary; Aortic Aneurysm, Abdominal; Astrocytoma; Blood Coagulation Disorders; Bone Neoplasms; Brain Injuries; Brain Neoplasms; Coronary Disease; Femoral Neck Fractures; Fractures, Bone; Gastrointestinal Hemorrhage; Genital Neoplasms, Female; Glioma; Head and Neck Neoplasms; Hematologic Neoplasms; Hematoma; Hematoma, Subdural, Intracranial; Hemoptysis; Hip Fractures; Ileus; Inflammation; Joint Diseases; Leiomyoma; Melanosis; Meningioma; Nasal Polyps; Neoplasms; Osteoarthritis; Pain; Pelvic Organ Prolapse; Placenta Accreta; Placenta Previa; Postpartum Hemorrhage; Scoliosis; Sepsis; Severe Acute Respiratory Syndrome; Shock; Shoulder Impingement Syndrome; Shoulder Pain; Telangiectasia, Hereditary Hemorrhagic; Thrombocytopenia; Wounds and Injuries; Hemophilia A; Hemorrhage; Menorrhagia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INHALATION; INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Renal Insufficiency; Gonorrhea; Enterobacteriaceae Infections; Skin Diseases; Bacterial Infections; Cystic Fibrosis; Infections; Intraabdominal Infections; Pneumonia; Pyelonephritis; Sepsis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hepatopulmonary Syndrome; Esophageal and Gastric Varices; Liver Cirrhosis; Peritonitis; Urinary Tract Infections; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dyspepsia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Depressive Disorder, Major; Gastroparesis; Marijuana Abuse; Sexual Dysfunction, Physiological; Spinal Cord Injuries; Apnea; Dementia; Depressive Disorder; Ischemic Stroke; Parkinson Disease; Schizophrenia; Anxiety
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Arachidonate 5-lipoxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: GASTROINTESTINAL; OTHER
THERAPEUTIC INDICATION: Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diverticulum, Colon; Eosinophilic Esophagitis; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis