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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: GASTROINTESTINAL; OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Anxiety Disorders; Infections; Pulmonary Disease, Chronic Obstructive; Breast Carcinoma In Situ; Endometrial Neoplasms; Protoporphyria, Erythropoietic; Dermatitis, Atopic; Gastrointestinal Hemorrhage; Hemorrhage; Ulcer; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-B receptor agonist
ROUTE OF ADMINISTRATION: INTRATHECAL; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Autistic Disorder; Liver Cirrhosis, Alcoholic; Obesity; Carcinoma, Hepatocellular; Cocaine-Related Disorders; Marijuana Abuse; Paget Disease, Extramammary; Pain; Tobacco Use Disorder; Alcoholism; Charcot-Marie-Tooth Disease; Gastroesophageal Reflux; Substance Withdrawal Syndrome; Brain Injuries; Brain Injuries, Traumatic; Cerebral Palsy; Multiple Sclerosis; Muscle Contraction; Muscle Rigidity; Muscle Spasticity; Spinal Cord Diseases; Spinal Cord Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Optic Neuritis; Urticaria; Angioedema; Dermatitis; Hypersensitivity; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: ATP-binding cassette sub-family A member 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Diabetic Nephropathies; Peripheral Arterial Disease; Hyperlipidemias; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 2a (5-HT2a) receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: MUSCULOSKELETAL; OTHER
THERAPEUTIC INDICATION: Migraine Disorders; Cerebral Palsy; Muscle Spasticity; Myalgia; Spasm; Spinal Cord Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alzheimer Disease; Depressive Disorder, Major; Obsessive-Compulsive Disorder; Substance-Related Disorders; Voice Disorders; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Delirium; Epilepsy; Epilepsy, Reflex; Pain; Seizures; Substance Withdrawal Syndrome; Dementia; Epilepsia Partialis Continua; Psychomotor Agitation; Psychotic Disorders; Schizophrenia; Vertigo; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Status Epilepticus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Prostaglandin E2 receptor agonist
ROUTE OF ADMINISTRATION: ENDOCERVICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Abortion, Incomplete; Pain; Pregnancy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRACRANIAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Leukemia, Plasma Cell; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neuroblastoma; Sezary Syndrome; Brain Neoplasms; Colorectal Neoplasms; Gliosarcoma; Graft vs Host Disease; Hematologic Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Ovarian Neoplasms; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stiff-Person Syndrome; Breast Neoplasms; Central Nervous System Neoplasms; Leukemia; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Oligodendroglioma; Astrocytoma; Ependymoma; Glioblastoma; Glioma; Hodgkin Disease; Medulloblastoma; Multiple Myeloma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CANCER; OTHER
THERAPEUTIC INDICATION: Brain Neoplasms; Hepatitis C, Chronic; Osteosarcoma; Adenoma; Amyotrophic Lateral Sclerosis; Central Nervous System Neoplasms; Fibromatosis, Aggressive; Glioblastoma; Glioma; Gynecomastia; HIV Infections; Hereditary Breast and Ovarian Cancer Syndrome; Infertility, Male; Melanoma; Neoplasms; Neuroendocrine Tumors; Pain; Retroperitoneal Fibrosis; Severe Acute Respiratory Syndrome; Telangiectasia, Hereditary Hemorrhagic; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Bipolar Disorder; Breast Neoplasms, Male; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Ovarian Epithelial; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hyperplasia; Hypertension; Infertility; Inflammatory Breast Neoplasms; Liver Neoplasms; Menopause; Muscular Dystrophy, Duchenne; Myocardial Ischemia; Neoplasm Metastasis; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Hypersensitivity; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis; Common Cold; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Urticaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis; Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bone Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder; Fibromyalgia; Liver Cirrhosis; Pain; Stress Disorders, Post-Traumatic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: ATP inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H2 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: ORAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atrophy; Hypogonadism; Menopause; Osteoporosis; Primary Ovarian Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dermatitis, Atopic; HIV Infections; Malaria; Neoplasms; Psoriasis; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Heart Diseases; Hypotension, Orthostatic; Obesity; Prader-Willi Syndrome; Premature Birth; Tachycardia, Ventricular; Ventricular Fibrillation; beta-Thalassemia; Atherosclerosis; Atrial Fibrillation; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 2; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; ST Elevation Myocardial Infarction; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atrial Fibrillation; Heart Diseases; Angina Pectoris; Heart Failure; Hypertension; Myocardial Infarction; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Eye Diseases; Hemorrhoids
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acute Lung Injury; Brain Injuries; Shock; Shock, Septic; Heart Failure; Cardiovascular Diseases