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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gram-Positive Bacterial Infections; Mastitis; Enterobacteriaceae Infections; Staphylococcal Infections; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Neuralgia; Purpura, Thrombocytopenic, Idiopathic; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M3 antagonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Mydriasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetic Cardiomyopathies; Heart Failure; Heart Failure, Diastolic; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-2 agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; PEDIATRICS
THERAPEUTIC INDICATION: Pain; Attention Deficit Disorder with Hyperactivity; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M1 agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Urinary Incontinence; Dry Eye Syndromes; Presbyopia; Glaucoma; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Miosis; Ocular Hypertension; Sjogren's Syndrome; Xerostomia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Amidophosphoribosyltransferase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER; PEDIATRICS
THERAPEUTIC INDICATION: Astrocytoma; Brain Neoplasms; Central Serous Chorioretinopathy; Glioblastoma; Obesity; Obesity, Morbid; Postoperative Complications; Syphilis, Congenital; Asthma; Bacteremia; Buruli Ulcer; Chlamydia Infections; Colitis, Ulcerative; Head and Neck Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Mastitis; Periapical Periodontitis; Pneumonia, Bacterial; Pseudomyxoma Peritonei; Tuberculosis; Tuberculosis, Pulmonary; Vaginosis, Bacterial; Abscess; Bronchitis, Chronic; Cholecystitis; Communicable Diseases; Dyspepsia; Endocarditis; Enterobacteriaceae Infections; Fever; Gastritis; Helicobacter Infections; Hemorrhage; Hepatitis, Alcoholic; Influenza, Human; Low Back Pain; Lymphoma, Non-Hodgkin; Malaria, Falciparum; Malnutrition; Neutropenia; Otitis Media, Suppurative; Periodontitis; Pyelonephritis; Severe Acute Respiratory Syndrome; Stomach Ulcer; Urinary Bladder Neoplasms; Bacterial Infections; Duodenal Ulcer; Gonorrhea; Infections; Otitis Media; Pharyngitis; Pneumonia; Respiratory Tract Infections; Sinusitis; Soft Tissue Infections; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Sclerosis; Fever; Tachycardia, Ventricular; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor modulator
ROUTE OF ADMINISTRATION: INJECTION; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Carcinoma, Squamous Cell; Hypertension; Laryngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Prostatic Neoplasms; Angina, Stable
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Parkinson Disease; Heart Failure; Myocardial Infarction; Renal Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine transporter releasing agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter releasing agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Enuresis; Common Cold; Cough; Hypersensitivity; Influenza, Human; Migraine Disorders; Nasal Obstruction; Pain; Rhinitis, Allergic, Seasonal; Sinusitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Dermatitis, Atopic; Sinusitis; Lichen Planus, Oral; Periarthritis; Eye Diseases; Hemorrhoids; Infections; Lung Diseases, Obstructive; Nasal Obstruction; Psoriasis; Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M2 antagonist
ROUTE OF ADMINISTRATION: TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Paget Disease, Extramammary; Rhinitis, Allergic, Seasonal; Sleep Apnea Syndromes; Sleep Apnea, Obstructive; Enuresis; Hyperhidrosis; Polyneuropathies; Urinary Bladder, Neurogenic; Polyuria; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Urge
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: ORAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Kidney Diseases; Folliculitis; Candidiasis, Oral; Candidiasis, Vulvovaginal; HIV Infections; Vaginal Discharge; Vaginosis, Bacterial; Candidiasis; Infections; Mycoses; Pruritus; Skin Diseases, Infectious; Tinea; Tinea Pedis; Tinea cruris
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: ORAL; TOPICAL; TRANSDERMAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; HIV Infections; Osteoporosis; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Urinary Tract Infections; Amenorrhea; Anorexia Nervosa; Atrophic Vaginitis; Atrophy; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Endometriosis; Hot Flashes; Infertility; Leiomyoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Dyspareunia; Hypogonadism; Primary Ovarian Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DOPA decarboxylase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Angelman Syndrome; Asthma; Hypertension; Hypotension, Orthostatic; Tobacco Use Disorder; Albinism, Oculocutaneous; Aphasia; Attention Deficit Disorder with Hyperactivity; Back Pain; Chronic Pain; Cocaine-Related Disorders; Fibromyalgia; Macular Degeneration; Multiple Sclerosis; Pain; Retinitis Pigmentosa; Schizophrenia; Spinal Cord Injuries; Amblyopia; Dysautonomia, Familial; Stroke; Parkinson Disease; Parkinson Disease, Postencephalitic; Parkinson Disease, Secondary; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M2 antagonist
ROUTE OF ADMINISTRATION: ORAL; TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Prostatic Neoplasms; Urinary Incontinence; Urinary Bladder, Overactive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Progesterone receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; INTRAMUSCULAR; SUBCUTANEOUS
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Pregnancy; Premature Birth
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: D2-like dopamine receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine transporter releasing agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: D2-like dopamine receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Pulmonary Disease, Chronic Obstructive; Tobacco Use Disorder; Migraine Disorders; Neuralgia; Anxiety; Delirium; Bipolar Disorder; Mental Disorders; Psychomotor Agitation; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Neuralgia; Marijuana Abuse; REM Sleep Behavior Disorder; Anxiety; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Epilepsy, Tonic-Clonic; Pain; Schizophrenia; Status Epilepticus; Epilepsy; Panic Disorder; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Attention Deficit Disorder with Hyperactivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INHALATION; OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Bronchopulmonary Dysplasia; Dry Eye Syndromes; Renal Insufficiency, Chronic; Sinusitis; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydropteroate synthetase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium/potassium-transporting ATPase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Angioedemas, Hereditary; Cytomegalovirus Infections; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epilepsy; Essential Hypertension; HIV Infections; Head and Neck Neoplasms; Hepatitis B, Chronic; Hepatitis C; Infections; Inflammation; Influenza, Human; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Nausea; Neoplasms; Pancreatic Neoplasms; Substance-Related Disorders; von Hippel-Lindau Disease; Arthritis, Rheumatoid; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Keratosis, Actinic; Non-alcoholic Fatty Liver Disease; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Tachycardia, Supraventricular; Atrial Fibrillation; Cardiovascular Diseases; Heart Failure
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Colonic Neoplasms; Kidney Neoplasms; Lung Neoplasms; Thyroid Neoplasms; Neuroendocrine Tumors; Leiomyosarcoma; Lymphoma; Lymphoma, T-Cell, Peripheral; Neuroblastoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Synovial; Skin Neoplasms; Hodgkin Disease; Melanoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bone Neoplasms; Breast Neoplasms; Glioma; Kidney Neoplasms; Neoplasm Metastasis; Sarcoma; Lung Neoplasms; Lymphoma; Lymphoma, AIDS-Related; Melanoma; Astrocytoma; Central Nervous System Neoplasms; Glioblastoma; Gliosarcoma; Leukemia, Myeloid, Acute; Medulloblastoma; Multiple Myeloma; Brain Neoplasms; Hodgkin Disease; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Colonic bacteria substrate
ROUTE OF ADMINISTRATION: ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Premature Birth; Dermatitis, Atopic; Liver Cirrhosis; Brain Diseases; Constipation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Osteoarthritis