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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Keloid; Cardiomyopathy, Dilated; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mineralocorticoid receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Intracranial Aneurysm; Cocaine-Related Disorders; Infertility; Muscle Cramp; Neurilemmoma; Stroke; Poisoning; Subarachnoid Hemorrhage; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Brain Neoplasms; Aortic Aneurysm, Thoracic; Stroke; Subarachnoid Hemorrhage; Hypertension; Muscle Cramp; Pre-Eclampsia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Prostanoid EP3 receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Abortion, Incomplete; Clostridium Infections; Muscle Cramp; Premature Birth; Abortion, Spontaneous; Leiomyoma; Menorrhagia; Myoma; Obesity; Pain; Postpartum Hemorrhage; Pre-Eclampsia; Pregnancy; Spondylitis, Ankylosing; Uterine Diseases; Duodenal Ulcer; Gastroesophageal Reflux; Hemorrhage; Osteoarthritis; Peptic Ulcer; Stomach Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Inflammation; Ischemia; Leukemia, Lymphocytic, Chronic, B-Cell; Cardiomyopathies; Coronary Disease; Pain; Respiratory Distress Syndrome; ST Elevation Myocardial Infarction; Takotsubo Cardiomyopathy; Angina, Stable; Atrial Fibrillation; Coronary Stenosis; Myocardial Infarction; Myocardial Ischemia; Neoplasms; Tachycardia, Ventricular; Cardiovascular Diseases; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Obsessive-Compulsive Disorder; Schizophrenia; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Colorectal Neoplasms; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human herpesvirus 1 DNA polymerase inhibitor
ROUTE OF ADMINISTRATION: IMPLANTATION; OPHTHALMIC; ORAL
STATUS: Approved
THERAPEUTIC AREA: EYE; OTHER
THERAPEUTIC INDICATION: Central Nervous System Neoplasms; Kidney Diseases; Melanoma; Mesothelioma; Neuroblastoma; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Glioblastoma; Graft vs Host Disease; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Conjunctivitis; Cytomegalovirus Infections; Infections; Acquired Immunodeficiency Syndrome; Cytomegalovirus Retinitis; Eye Infections; HIV Infections; Primary Immunodeficiency Diseases; Retinitis; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Bipolar Disorder; Dementia; Depressive Disorder; Developmental Disabilities; Intellectual Disability; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Adrenal Hyperplasia, Congenital; Ovarian Neoplasms; Polycystic Ovary Syndrome; Prostatic Neoplasms, Castration-Resistant; Carcinoma; Neoplasms; Prostatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Monoamine oxidase B inhibitor
ROUTE OF ADMINISTRATION: TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Prostatic Neoplasms; Tobacco Use Disorder; Borderline Personality Disorder; Cocaine-Related Disorders; Depressive Disorder; Depressive Disorder, Major; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gliosarcoma; Leukoencephalopathy, Progressive Multifocal; Pneumonia, Viral; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Malaria, Falciparum; Schistosomiasis haematobia; Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Chronic Pain; Diabetic Retinopathy; Hypoxia; Conjunctivitis, Viral; Heart Diseases; Miosis; Musculoskeletal Diseases; Osteoarthritis, Knee; Pancreatitis; Periodontitis; Pre-Eclampsia; Retinopathy of Prematurity; Rotator Cuff Injuries; Scoliosis; Tonsillitis; Abdominal Pain; Back Pain; Breast Neoplasms; Cataract; Deglutition Disorders; Headache; Inflammation; Kidney Calculi; Migraine Disorders; Pain; Wounds and Injuries; Eye Diseases; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amnesia; Colorectal Neoplasms; Depressive Disorder, Major; Inflammation; Premature Birth; Renal Insufficiency; Renal Insufficiency, Chronic; Scoliosis; Sepsis; Shock; Shock, Septic; Sleep Initiation and Maintenance Disorders; Coronary Disease; Depressive Disorder, Treatment-Resistant; Hypotension; Intestinal Polyps; Leukemia; Lung Neoplasms; Migraine Disorders; Obesity, Morbid; Sleep Apnea, Obstructive; Strabismus; Tonsillitis; Wounds and Injuries; Adenomatous Polyposis Coli; Back Pain; Brain Injuries; Breast Neoplasms; Esophageal Neoplasms; Genital Neoplasms, Male; Heart Diseases; Hypertension; Intracranial Aneurysm; Liver Cirrhosis; Neoplasms; Obesity; Pain; Pancreatic Neoplasms; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Status Epilepticus; Stroke; Subarachnoid Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sulfonylurea receptor 2, Kir6.2 opener
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Potassium-transporting ATPase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: GASTROINTESTINAL; OTHER
THERAPEUTIC INDICATION: Alzheimer Disease; Anemia; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; HIV Infections; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Cystic Fibrosis; Gastrinoma; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Neoplasms; HIV Infections; Liver Abscess; Syphilis; Bacterial Infections; Bronchitis; Bronchitis, Chronic; Gonorrhea; Infections; Otitis Media; Pharyngitis; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Progesterone receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cystic Fibrosis; HIV Infections; Hepatitis C; Migraine Disorders; Metrorrhagia; Osteoporosis; Neural Tube Defects; Acne Vulgaris
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS; IV (INFUSION)
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma; Esophageal Neoplasms; Neuroblastoma; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Trypanosomiasis, African; Uterine Cervical Neoplasms; Adenomatous Polyposis Coli; Astrocytoma; Colorectal Neoplasms; Precancerous Conditions; Urinary Bladder Neoplasms; Leishmaniasis; Trypanosomiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lymphoma; Sarcoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated L-type calcium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Opioid-Related Disorders; Substance-Related Disorders; Bipolar Disorder; Parkinson Disease; Cardiovascular Diseases; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Spondylitis, Ankylosing
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Blast Crisis; Carcinoma, Hepatocellular; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Neutropenia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Erectile Dysfunction; Substance-Related Disorders; Alcoholism; Cocaine-Related Disorders; Heart Diseases; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Diabetes Mellitus; Heart Failure; Hypercholesterolemia; Kidney Calculi; Myocardial Infarction; Myocardial Ischemia; Prostatic Hyperplasia; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acne Vulgaris; Anemia, Aplastic; Carcinoma, Hepatocellular; Severe Acute Respiratory Syndrome; Helminthiasis