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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase-2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome b inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Non-Small-Cell Lung; Gastroesophageal Reflux; Severe Acute Respiratory Syndrome; Toxoplasmosis, Cerebral; Malaria, Falciparum; Malaria; Pneumocystis Infections; Pneumonia, Pneumocystis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Prostatic Neoplasms, Castration-Resistant; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anovulation; Arthritis, Rheumatoid; Fibromyalgia; Idiopathic Pulmonary Fibrosis; Myocardial Infarction; Tinnitus; Agoraphobia; Alcoholism; Anxiety; Anxiety Disorders; Bipolar Disorder; Dementia; Depressive Disorder, Major; Hepatitis C, Chronic; Neuralgia; Obsessive-Compulsive Disorder; Panic Disorder; Parkinson Disease; Phobia, Social; Schizophrenia; Stress Disorders, Post-Traumatic; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Familial Primary Pulmonary Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Breast Neoplasms; Hypertension; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Alzheimer Disease; Asthma; Cachexia; Celiac Disease; Cystic Fibrosis; Glioblastoma; Heart Failure; Hepatitis B, Chronic; Hepatitis C, Chronic; Infections; Inflammatory Bowel Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Malaria; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neoplasm Metastasis; Neuralgia; Polycystic Ovary Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Syncytial Virus Infections; Sporotrichosis; Thrombosis; Aspergillosis, Allergic Bronchopulmonary; Burns; Carcinoma, Basal Cell; Carcinoma, Non-Small-Cell Lung; Coccidioidomycosis; Crohn Disease; Hematologic Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Meningitis, Cryptococcal; Mycetoma; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Sinusitis; Tinea Pedis; Tinea Versicolor; Cryptococcosis; Histoplasmosis; Neoplasms; Aspergillosis; Blastomycosis; Candidiasis; Lung Diseases; Mycoses; Onychomycosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Postoperative Complications; Renal Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Erectile Dysfunction; HIV Infections; Hyperlipidemias; Kidney Diseases; Pancreatitis; Aortic Aneurysm, Abdominal; Aortic Valve Insufficiency; Cardiomyopathy, Hypertrophic; Dystonic Disorders; Heart Diseases; Hyperaldosteronism; Liver Diseases; Raynaud Disease; Thalassemia; beta-Thalassemia; Atherosclerosis; Coronary Disease; Depressive Disorder; Diabetes Mellitus; Diabetes Mellitus, Type 2; Essential Hypertension; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Infarction; Myocardial Ischemia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: HIV Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanosis; Skin Neoplasms; Sunburn
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sunscreen
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Eye Manifestations; Lung Diseases, Obstructive; Nasal Obstruction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dystonic Disorders; Low Back Pain; Marijuana Abuse; Obesity; Prostatic Neoplasms; Parkinson Disease; Substance-Related Disorders; Anxiety; Attention Deficit Disorder with Hyperactivity; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lecithin Cholesterol Acyltransferase Deficiency; Muscular Dystrophy, Duchenne; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Squalene monooxygenase inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Mycoses; Colitis, Ulcerative; Crohn Disease; Tinea Pedis; Onychomycosis; Tinea
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA topoisomerase II inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Leukemia; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanosis; Skin Neoplasms; Sunburn
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA-directed RNA polymerase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Tuberculosis, Pulmonary; Crohn Disease; Infections; Mycobacterium Infections; Mycoses; HIV Infections; Mycobacterium avium-intracellulare Infection; Tuberculosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Progesterone receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sleep Apnea, Central; Amenorrhea; Hemorrhage; Polycystic Ovary Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Steroid 5-alpha-reductase 2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Hypogonadism; Acne Vulgaris; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms, Castration-Resistant; Retinal Diseases; Alopecia; Prostatic Hyperplasia; Prostatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Tachycardia, Ventricular; Ventricular Fibrillation; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tubulin inhibitor
ROUTE OF ADMINISTRATION: INJECTION; IV (INFUSION)
STATUS: Approved
THERAPEUTIC AREA: CANCER; OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Anus Neoplasms; Bone Neoplasms; Brain Neoplasms; Carcinoid Tumor; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Verrucous; Coronary Restenosis; Genital Neoplasms, Female; Glioblastoma; Glioma; Gliosarcoma; Hodgkin Disease; Hypertension; Hypopharyngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Mesothelioma; Rectal Neoplasms; Vaginal Neoplasms; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Neoplasms; Arthritis, Rheumatoid; Biliary Tract Neoplasms; Breast Carcinoma In Situ; Carcinoma, Ductal; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Cholangiocarcinoma; Colorectal Neoplasms; Constriction, Pathologic; Cystadenoma, Serous; Digestive System Diseases; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Keratosis, Actinic; Kidney Neoplasms; Leukemia; Lymphoma; Mouth Neoplasms; Multiple Myeloma; Neoplasms, Complex and Mixed; Neoplasms, Germ Cell and Embryonal; Oropharyngeal Neoplasms; Penile Neoplasms; Peripheral Vascular Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Psoriasis; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Thymoma; Vulvar Neoplasms; Adenocarcinoma of Lung; Anemia; Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Diabetes Mellitus, Type 1; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gestational Trophoblastic Disease; HIV Infections; Head and Neck Neoplasms; Hypersensitivity; Inflammatory Breast Neoplasms; Ischemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pain; Pancreatic Neoplasms; Peripheral Arterial Disease; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Sarcoma, Kaposi; Sex Cord-Gonadal Stromal Tumors; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Otitis Media
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Eye Manifestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Kidney Diseases; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Influenza, Human; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Pyelonephritis; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Urinary Tract Infections; Bacterial Infections