LEVORPHANOL

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Synonyms
Status
Molecule Category Free-form
UNII 27618J1N2X
EPA CompTox DTXSID3023213

Structure

InChI Key JAQUASYNZVUNQP-USXIJHARSA-N
Smiles CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13
InChI
InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H23NO
Molecular Weight 257.38
AlogP 3.08
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Polar Surface Area 23.47
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 19.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Voltage-gated ion channel Voltage-gated sodium channel
- - - - 33
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor
- 0.004-278 - 0.21-10 -
Membrane receptor
- 0.004-278 - 0.21-10 -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cavia porcellus
- 0.6-17 - 0.21-4.2 33
Cricetulus griseus
- - - 0.21-4.2 -
Homo sapiens
- - - 0.21-4.2 -
Mus musculus
- 278 - 0.3-1.9 -

Related Entries

Cross References

Resources Reference
ChEBI 6444
ChEMBL CHEMBL592
DrugBank DB00854
DrugCentral 1574
FDA SRS 27618J1N2X
Human Metabolome Database HMDB0014992
Guide to Pharmacology 7595
KEGG C08014
PharmGKB PA164744368
PubChem 5359272
SureChEMBL SCHEMBL24335
ZINC ZINC000003812984
CONTENTS