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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Multiple Sclerosis; Rhinitis, Allergic, Seasonal; Inflammation; Lymphoma, Non-Hodgkin; Osteoarthritis, Knee; Pterygium
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasm Metastasis; Neuroendocrine Tumors
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Altitude Sickness; Hypertension, Pulmonary; Premature Birth; Heart Arrest; Acute Kidney Injury; Headache; Asthma; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Hypertension, Pulmonary; Leukemia, Myeloid, Acute; Prostatic Neoplasms; Altitude Sickness; Apnea; Kidney Diseases; Leukemia; Pseudohypoparathyroidism; Renal Insufficiency, Chronic; Virus Diseases; Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency; Asthma; Bronchitis, Chronic; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Burns; Toxoplasmosis, Cerebral; Chorioretinitis; Toxoplasmosis, Congenital; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin D receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alopecia Areata; Colitis, Ulcerative; Colorectal Neoplasms; Inflammatory Bowel Diseases; Lung Neoplasms; Neoplasms; Osteogenesis Imperfecta; Penile Induration; Premature Birth; Sarcopenia; Anemia, Sickle Cell; Blood Coagulation Disorders; Crohn Disease; Death, Sudden, Cardiac; Diabetes Mellitus; Diabetic Neuropathies; Disseminated Intravascular Coagulation; Endometrial Neoplasms; Giant Cell Tumor of Bone; Giant Cell Tumors; HIV Infections; Heart Failure; Hepatitis C; Hyperparathyroidism, Primary; Insulin Resistance; Latent Autoimmune Diabetes in Adults; Lupus Erythematosus, Cutaneous; Malnutrition; Migraine Disorders; Neuralgia; Optic Neuritis; Prostatic Neoplasms; Restless Legs Syndrome; Spinal Cord Injuries; Uterine Cervical Neoplasms; Alzheimer Disease; Asthma; Bone Diseases, Metabolic; Breast Neoplasms; Burns; Colonic Neoplasms; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Familial Hypophosphatemic Rickets; Femoral Neck Fractures; Fractures, Bone; Hepatitis C, Chronic; Hip Fractures; Hyperprolactinemia; Hypocalcemia; Leukemia; Lipid Metabolism Disorders; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Osteitis Deformans; Osteoarthritis, Knee; Osteoporosis; Osteoporosis, Postmenopausal; Pain; Polycystic Ovary Syndrome; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Tuberculosis; Tuberculosis, Pulmonary; Vitamin D Deficiency; Hypoparathyroidism; Hypophosphatemia, Familial; Rickets, Hypophosphatemic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: CANCER; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Scoliosis; Ischemic Stroke; Sciatica; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Attention Deficit Disorder with Hyperactivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Eye Infections; Leishmaniasis; Trypanosomiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acne Vulgaris; Conjunctivitis; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated T-type calcium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Crohn Disease; Depressive Disorder, Major; Fibrosis; Glycogen Storage Disease Type II; Hyperuricemia; Immune System Diseases; Lung Neoplasms; Purpura, Thrombocytopenic, Idiopathic; alpha 1-Antitrypsin Deficiency; Alcoholism; Autistic Disorder; Breast Carcinoma In Situ; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Cocaine-Related Disorders; Endometrial Neoplasms; Graft vs Host Disease; Hepatitis B, Chronic; Immunoglobulin G4-Related Disease; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Restless Legs Syndrome; Stomach Neoplasms; Stomatitis, Aphthous; Anxiety; Cough; Dementia; Depressive Disorder; Inflammation; Kidney Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis; Migraine Disorders; Multiple Sclerosis, Chronic Progressive; Pain; Rhinitis; Schizophrenia; Stomatitis; Urticaria; Hypersensitivity; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Heavy metals chelating agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D1 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Buruli Ulcer; Mycobacterium avium-intracellulare Infection; Plague; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Migraine with Aura; Migraine without Aura; Migraine Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thyroid peroxidase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Graves Ophthalmopathy; Thyrotoxicosis; Hyperthyroidism; Thyroid Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis C; Premature Birth; Neonatal Abstinence Syndrome; Restless Legs Syndrome; Adenocarcinoma; Chronic Pain; Cocaine-Related Disorders; HIV Infections; Heroin Dependence; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Opioid-Related Disorders; Renal Insufficiency, Chronic; Scoliosis; Pain; Substance-Related Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Eosinophilic Esophagitis; Pancreatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alcoholism; Amblyopia; Amyotrophic Lateral Sclerosis; Anemia; Arthritis, Rheumatoid; Chronic Pain; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus, Type 2; Endotoxemia; HIV Infections; Hepatitis C, Chronic; Hypotension, Orthostatic; Melanoma; Mitochondrial Diseases; Narcolepsy; Neoplasms; Non-alcoholic Fatty Liver Disease; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Spinal Cord Injuries; Substance-Related Disorders; Breast Neoplasms; Cocaine-Related Disorders; Dyspnea; Memory Disorders; Tension-Type Headache; Alzheimer Disease; Atrial Fibrillation; Back Pain; Common Cold; Coronary Disease; Dysmenorrhea; Headache; Hypoxia; Intermittent Claudication; Low Back Pain; Migraine with Aura; Migraine without Aura; Multiple Sclerosis, Relapsing-Remitting; Neck Pain; Obesity; Parkinson Disease; Toothache; Apnea; Attention Deficit Disorder with Hyperactivity; Migraine Disorders; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Migraine Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: BUCCAL; ORAL; RECTAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DENTISTRY; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glycogen Storage Disease Type II; Hypertension, Pulmonary; Keratosis, Actinic; Lung Neoplasms; Neoplasms, Cystic, Mucinous, and Serous; Neuroma; Premature Birth; Thromboembolism; Anus Diseases; Anxiety; Carcinoma; Cocaine-Related Disorders; Cognitive Dysfunction; Cystitis, Interstitial; Diabetic Neuropathies; Dysmenorrhea; Heart Diseases; Humeral Fractures; Infertility; Irritable Bowel Syndrome; Leiomyoma; Macular Degeneration; Myofascial Pain Syndromes; Neoplasms; Osteoarthritis, Knee; Renal Colic; Rib Fractures; Scleroderma, Localized; Severe Acute Respiratory Syndrome; Shoulder Impingement Syndrome; Shoulder Pain; Skin Diseases; Temporomandibular Joint Disorders; Trigeminal Neuralgia; Urinary Incontinence; Urinary Tract Infections; Breast Neoplasms; Carpal Tunnel Syndrome; Chronic Pain; Colorectal Neoplasms; Common Cold; Cough; Dysuria; Fibromyalgia; Headache; Heart Arrest; Hemorrhage; Ileus; Low Back Pain; Migraine Disorders; Muscular Diseases; Nutrition Disorders; Obesity; Obesity, Morbid; Osteoporosis, Postmenopausal; Paget Disease, Extramammary; Parathyroid Diseases; Periarthritis; Peripheral Nervous System Diseases; Pharyngitis; Pre-Eclampsia; Pregnancy; Pulpitis; Scoliosis; Shock, Septic; Sinusitis; Stomatitis; Stroke; Tennis Elbow; Urinary Bladder, Overactive; Uterine Cervical Dysplasia; Wounds and Injuries; Arrhythmias, Cardiac; Arthritis; Back Pain; Burns; Bursitis; Hemorrhoids; Inflammation; Insect Bites and Stings; Muscle Cramp; Myalgia; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis; Pain; Premature Ejaculation; Pruritus; Rectal Diseases; Sprains and Strains; Sunburn; Tendinopathy; Urethritis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Sepsis; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity; Pruritus