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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mineralocorticoid receptor agonist
ROUTE OF ADMINISTRATION: IMPLANTATION; INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Multiple Sclerosis; Rhinitis, Allergic, Seasonal; Inflammation; Lymphoma, Non-Hodgkin; Osteoarthritis, Knee; Pterygium
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated potassium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Small Cell; Lambert-Eaton Myasthenic Syndrome; Muscle Weakness
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasm Metastasis; Neuroendocrine Tumors
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Hypertension, Pulmonary; Leukemia, Myeloid, Acute; Prostatic Neoplasms; Altitude Sickness; Apnea; Kidney Diseases; Leukemia; Pseudohypoparathyroidism; Renal Insufficiency, Chronic; Virus Diseases; Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency; Asthma; Bronchitis, Chronic; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Altitude Sickness; Hypertension, Pulmonary; Premature Birth; Heart Arrest; Acute Kidney Injury; Headache; Asthma; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Burns; Toxoplasmosis, Cerebral; Chorioretinitis; Toxoplasmosis, Congenital; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin D receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alopecia Areata; Colitis, Ulcerative; Colorectal Neoplasms; Inflammatory Bowel Diseases; Lung Neoplasms; Neoplasms; Osteogenesis Imperfecta; Penile Induration; Premature Birth; Sarcopenia; Anemia, Sickle Cell; Blood Coagulation Disorders; Crohn Disease; Death, Sudden, Cardiac; Diabetes Mellitus; Diabetic Neuropathies; Disseminated Intravascular Coagulation; Endometrial Neoplasms; Giant Cell Tumor of Bone; Giant Cell Tumors; HIV Infections; Heart Failure; Hepatitis C; Hyperparathyroidism, Primary; Insulin Resistance; Latent Autoimmune Diabetes in Adults; Lupus Erythematosus, Cutaneous; Malnutrition; Migraine Disorders; Neuralgia; Optic Neuritis; Prostatic Neoplasms; Restless Legs Syndrome; Spinal Cord Injuries; Uterine Cervical Neoplasms; Alzheimer Disease; Asthma; Bone Diseases, Metabolic; Breast Neoplasms; Burns; Colonic Neoplasms; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Familial Hypophosphatemic Rickets; Femoral Neck Fractures; Fractures, Bone; Hepatitis C, Chronic; Hip Fractures; Hyperprolactinemia; Hypocalcemia; Leukemia; Lipid Metabolism Disorders; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Osteitis Deformans; Osteoarthritis, Knee; Osteoporosis; Osteoporosis, Postmenopausal; Pain; Polycystic Ovary Syndrome; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Tuberculosis; Tuberculosis, Pulmonary; Vitamin D Deficiency; Hypoparathyroidism; Hypophosphatemia, Familial; Rickets, Hypophosphatemic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: CANCER; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mu opioid receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hypotension; Acute Pain; Pain; Substance-Related Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Scoliosis; Ischemic Stroke; Sciatica; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Attention Deficit Disorder with Hyperactivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Opioid receptors; mu/kappa/delta agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Kidney Diseases; Liver Diseases; Substance-Related Disorders; Osteoarthritis; Rotator Cuff Injuries; Wounds and Injuries; Chronic Pain; Low Back Pain; Neuralgia; Acute Pain; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Monoamine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acne Vulgaris; Conjunctivitis; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Eye Infections; Leishmaniasis; Trypanosomiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscle-type nicotinic acetylcholine receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 1d (5-HT1d) receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; NASAL
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Migraine Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Heavy metals chelating agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Chancroid; Granuloma Inguinale; Infections; Plague; Pneumonia; Tuberculosis; Tularemia; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated T-type calcium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Migraine with Aura; Migraine without Aura; Migraine Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Venous Insufficiency; Varicose Veins