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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dementia; Depressive Disorder; Schizophrenia; Anxiety
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Lipoma; Orthostatic Intolerance; Atrial Fibrillation; Kidney Calculi; Cardiovascular Diseases; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cardiotoxicity; Genital Neoplasms, Female; Headache; Migraine Disorders; Nausea; Anxiety; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Hypogonadism; Neoplasms; Orchitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Synaptic vesicular amine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Aging; Autistic Disorder; Alcoholism; Depressive Disorder, Major; Macular Degeneration; Tobacco Use Disorder; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thyroid hormone receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Heart Failure; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Breast Neoplasms; Euthyroid Sick Syndromes; Hypothyroidism; Shock, Septic; Bipolar Disorder; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Acetylcholinesterase inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Diabetic Retinopathy; Macular Degeneration; Nasal Polyps; Optic Neuropathy, Ischemic; Rotator Cuff Injuries; Abdominal Pain; Acneiform Eruptions; Alopecia Areata; Dermatitis, Atopic; Lichen Planus, Oral; Melanoma; Melanosis; Osteoarthritis, Knee; Psoriasis; Shoulder Pain; Vascular Diseases; Vitiligo; Wet Macular Degeneration; Corneal Edema; Keloid; Macular Edema; Orbital Pseudotumor; Osteoarthritis; Osteoarthritis, Hip; Pain; Pancreatitis, Chronic; Pulmonary Disease, Chronic Obstructive; Radiculopathy; Retinal Vein Occlusion; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Diseases; Hemorrhoids; Lung Diseases, Obstructive; Nasal Obstruction; Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: D2-like dopamine receptor antagonist
ROUTE OF ADMINISTRATION: RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colonic Neoplasms; Delirium; Glioblastoma; Neonatal Abstinence Syndrome; Severe Acute Respiratory Syndrome; Conduct Disorder; Porphyrias; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Low Back Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Synaptic vesicular amine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Common Cold; Cough; Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin K-dependent gamma-carboxylase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Hepatocellular; Smoking Cessation; Vertigo; Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Melanoma; Venous Thrombosis; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Anxiety; Dementia; Depressive Disorder; Psychomotor Agitation; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated T-type calcium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atherosclerosis; Chemical and Drug Induced Liver Injury; Cognitive Dysfunction; DiGeorge Syndrome; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Hearing Loss, Noise-Induced; Hyperuricemia; Immune System Diseases; Mucocutaneous Lymph Node Syndrome; Muscular Diseases; Myasthenia Gravis; Optic Nerve Diseases; Ovarian Hyperstimulation Syndrome; Parkinson Disease; Stiff-Person Syndrome; Adenomatous Polyposis Coli; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Appendicitis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Carpal Tunnel Syndrome; Coronavirus Infections; Death, Sudden, Cardiac; Fallopian Tube Neoplasms; Fanconi Anemia; Fasciitis, Plantar; Graves Ophthalmopathy; Hantavirus Infections; Hepatitis, Alcoholic; Hyperlipoproteinemia Type I; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, AIDS-Related; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Meniere Disease; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Nasal Polyps; Neoplasms; Neuromyelitis Optica; Ovarian Neoplasms; Prostatic Neoplasms; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Sinusitis; Spasms, Infantile; Spondylarthropathies; Spondylitis, Ankylosing; Abdominal Pain; Aging; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Bell Palsy; Bronchopulmonary Dysplasia; Deglutition Disorders; Dermatomyositis; Edema; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Arrest; Heart Diseases; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hodgkin Disease; Ischemic Stroke; Kidney Diseases; Language Disorders; Leukemia; Leukemia, Biphenotypic, Acute; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Macrophage Activation Syndrome; Microscopic Polyangiitis; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myocarditis; Optic Neuritis; Optic Neuropathy, Ischemic; Pain; Pneumonia, Pneumocystis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Pulpitis; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Respiratory Tract Diseases; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Specific Language Disorder; Spinal Cord Injuries; Thrombocytopenia; Urinary Tract Infections; Vestibular Neuronitis; Acne Vulgaris; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Inflammation; Multiple Sclerosis; Osteoarthritis; Pneumonia; Tenosynovitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Carbonic anhydrase I inhibitor
ROUTE OF ADMINISTRATION: IM-IV; INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Liver Cirrhosis; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Pancreatic Ductal; Lymphoma, Mantle-Cell; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Stomach Neoplasms; Hodgkin Disease; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sulfonylurea receptor 1, Kir6.2 blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Diabetes Mellitus; Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: INTRAOCULAR; INTRAVITREAL; OPHTHALMIC; ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: EYE; OTHER
THERAPEUTIC INDICATION: Adrenal Insufficiency; Anaphylaxis; Aortic Coarctation; Brain Edema; Esophageal Neoplasms; Graves Disease; Head and Neck Neoplasms; Heart Failure; Hyperuricemia; Lacrimal Apparatus Diseases; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Osteoarthritis, Knee; Retinopathy of Prematurity; Rheumatic Diseases; Rotator Cuff Injuries; Scleritis; Sepsis; Sinusitis; Vitiligo; Appendicitis; Blast Crisis; Brain Neoplasms; Breast Carcinoma In Situ; Burkitt Lymphoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Castleman Disease; Cholangiocarcinoma; Dry Eye Syndromes; Dyspnea; Endocrine Gland Neoplasms; Endometrial Neoplasms; Fasciitis, Plantar; Glomerulonephritis; Gout; Hearing Loss; Hearing Loss, Sensorineural; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hemorrhage; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; IgA Vasculitis; Intestinal Obstruction; Intracranial Hypertension; Kidney Diseases; Leptospirosis; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Plasma Cell; Leukemia, T-Cell; Leukemia-Lymphoma, Adult T-Cell; Lichen Planus; Liposarcoma, Myxoid; Liver Neoplasms; Lung Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Meningitis; Meningitis, Cryptococcal; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neck Pain; Neoplasm Metastasis; Nervous System Diseases; POEMS Syndrome; Pancreatic Neoplasms; Premature Birth; Pulmonary Fibrosis; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Rectal Neoplasms; Red-Cell Aplasia, Pure; Respiratory Tract Diseases; Retinal Vein Occlusion; Stomach Neoplasms; Tonsillitis; Toxoplasmosis, Cerebral; Tuberculosis; Urinary Bladder Neoplasms; Uveitis, Intermediate; Wet Macular Degeneration; Xerostomia; Amyloidosis; Amyloidosis, Familial; Anemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Atrioventricular Block; Back Pain; Blepharitis; Breast Neoplasms; Bronchiolitis; Bronchopulmonary Dysplasia; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cataract; Chronic Pain; Colorectal Neoplasms; Conjunctivitis, Viral; Corneal Edema; Cysticercosis; Deafness; Deglutition Disorders; Dermatitis; Encephalitis, Herpes Simplex; Fatigue; Genital Neoplasms, Female; Genital Neoplasms, Male; Glaucoma; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granuloma, Lethal Midline; HELLP Syndrome; Headache; Hernias, Diaphragmatic, Congenital; Hodgkin Disease; Hypersensitivity; Immunoglobulin Light-chain Amyloidosis; Knee Injuries; Leiomyoma; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lichen Planus, Oral; Liver Cirrhosis; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Mastoiditis; Meniere Disease; Migraine Disorders; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Myelodysplastic Syndromes; Nausea; Nephrosis; Neuralgia; Otitis Externa; Otitis Media; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pain; Pelvic Organ Prolapse; Plasmacytoma; Pneumonia, Viral; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Rhinitis, Allergic, Perennial; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Smoldering Multiple Myeloma; Specific Language Disorder; Strabismus; Subarachnoid Hemorrhage; Urinary Tract Infections; Uveitis, Anterior; Vaginosis, Bacterial; Vitreoretinopathy, Proliferative; Vomiting; Waldenstrom Macroglobulinemia; Wounds and Injuries; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis Herpetiformis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis, Seborrheic; Diabetic Retinopathy; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Infections; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thiazide-sensitive sodium-chloride cotransporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Heart Diseases; Hypercholesterolemia; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Nephrotic Syndrome; Toxemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown