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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Aldehyde dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Fatigue; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Low Back Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sulfonylurea receptor 1, Kir6.2 blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Chronic Pain; Endotoxemia; Hepatitis C, Chronic; Lymphoma; Neoplasms; Diabetes Mellitus; Diabetes Mellitus, Type 2
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Unknown
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Asthma; Breast Neoplasms; Hypotension, Orthostatic; Lecithin Cholesterol Acyltransferase Deficiency; Prostatic Neoplasms, Castration-Resistant; Carcinoma, Squamous Cell; Histiocytosis, Langerhans-Cell; Melanoma; Pancreatitis, Chronic; Prostatic Neoplasms; Squamous Intraepithelial Lesions; Toothache; Alzheimer Disease; Hemorrhage; Inflammation; Pancreatitis; Premature Birth; Renal Colic; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Acute Pain; Arthralgia; Arthritis, Gouty; Arthritis, Rheumatoid; Cardiovascular Diseases; Ductus Arteriosus, Patent; Eye Diseases; Myalgia; Osteoarthritis; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Dementia; Depressive Disorder; Schizophrenia; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Substance Withdrawal Syndrome; Urinary Bladder, Neurogenic; Amphetamine-Related Disorders; Severe Acute Respiratory Syndrome; Tobacco Use Disorder; Alcoholism; Kidney Calculi; Stress Disorders, Post-Traumatic; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Constipation; Metabolic Syndrome; Neoplasms; Substance-Related Disorders; Thrombosis; Anus Diseases; Cardiomyopathy, Hypertrophic; Fissure in Ano; Influenza, Human; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Ischemia; Reperfusion Injury; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Hemorrhoids
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Colonic Neoplasms; Leukemia, Myeloid, Acute; Adenomatous Polyposis Coli; Colorectal Neoplasms; Prostatic Neoplasms; Diabetic Nephropathies; Severe Acute Respiratory Syndrome; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arrhythmogenic Right Ventricular Dysplasia; Atrial Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Bipolar Disorder; Dementia; Depressive Disorder; Developmental Disabilities; Intellectual Disability; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amnesia; Colorectal Neoplasms; Depressive Disorder, Major; Inflammation; Premature Birth; Renal Insufficiency; Renal Insufficiency, Chronic; Scoliosis; Sepsis; Shock; Shock, Septic; Sleep Initiation and Maintenance Disorders; Coronary Disease; Depressive Disorder, Treatment-Resistant; Hypotension; Intestinal Polyps; Leukemia; Lung Neoplasms; Migraine Disorders; Obesity, Morbid; Sleep Apnea, Obstructive; Strabismus; Tonsillitis; Wounds and Injuries; Adenomatous Polyposis Coli; Back Pain; Brain Injuries; Breast Neoplasms; Esophageal Neoplasms; Genital Neoplasms, Male; Heart Diseases; Hypertension; Intracranial Aneurysm; Liver Cirrhosis; Neoplasms; Obesity; Pain; Pancreatic Neoplasms; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Status Epilepticus; Stroke; Subarachnoid Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Dry Eye Syndromes; Lung Neoplasms; Neoplasms; Schizophrenia; Smoking Cessation; Tobacco Use Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphodiesterase 4 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Depressive Disorder; Psychotic Disorders; Schizophrenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Muscle Spasticity; Arthralgia; Myalgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Investigational
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Irritable Bowel Syndrome; Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatocyte nuclear factor 4-alpha activator
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acute Kidney Injury; Neoplasms; Pain; Thromboembolism; Arthralgia; Myalgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Essential Hypertension; Hypertension; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pain; Breast Neoplasms; Arthralgia; Myalgia; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Depressive Disorder; Schizophrenia; Psychotic Disorders