EcoDrugPlus(EcoDrug+) Data Sources

Drugs@FDA Active Ingredient Dosage Information Approval history

Orange Book Approved Drugs Patents Information

PubChem Chemical Synonyms Compound structure

ClinicalTrials.gov Investigational Drugs Information Indications for maximum phase demographic Information

Uniprot Uniport ID Gene Identifier Sequence

PHARMS-UBA Monitoring Data

Reactome Biological Pathway

HUGO Gene Nomenclature Committee Approved Gene symbol

FDA Substance registration system Unique ingredient identifier(UNII)

IUPHAR/BPS guide to pharmacology Approved drugs Primary Targets

Ensembl Orthologues Gene Gene Synonyms Query Percentage sequence Identity Target Percentage sequence Identity Chromosome Location

ChEMBL Approved Drugs related information Compound Structure Target Class Biological Activities Mechanism of Actions Available metabolites Plant protection products

NORMAN SUSDAT Biocides Drugs of abuse Food additives Food contact chemicals Human metabolites Human neurotoxins Indoor environment substances Industrial chemicals Natural toxins Personal care products Plant protection products Plastic additive Surfactant Drinking water chemical


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).