CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 22
Ensembl ID : ENSMUSG00000061740
Gene Symbol: CYP2D22
UniProtKB Entry: Q9JKY7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d22|ENSMUSG00000061740
MRLPTGAELWPIAIFTVIFLILVNLMHWRQRWTAHYPPGPMPWPVLGNLLHMDFQNMPAG

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VKC7-F1 Predicted 1-240 pLDDT 86.25
AlphaFold DB AF-Q9JKY7-F1 Predicted 1-500 pLDDT 91.5
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Expression Atlas ENSMUSG00000061740
MGI Symbol MGI:1929474
NCBI gene (formerly Entrezgene) 56448
UniProtKB Gene Name Q9JKY7
UniProtKB Gene Name Q9JKY7
WikiGene 56448
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 11
Ensembl ID : ENSMUSG00000068085
Gene Symbol: CYP2D11
UniProtKB Entry: P24457
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d11|ENSMUSG00000068085
MELLTGAGLWSVAIFTVIFILLVDLMHRHQHWTSRCPPGPVPWPVLGNLLQVDLGNMPYS LYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQ GVVLAPYGPEWQEQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQSINPNTM LNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIPGLA DMVFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNPESSFNDENLRM VVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVQHPEMADQARMPYTN AVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHP EHFLDAQGHFVKPEAFMPFSAGHRSCLGEALARMELFLFFTCLLQRFSISVPDGQPQPSN YRVHAIPVAPFPYQLCAVMREQGH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P24457-F1 Predicted 1-504 pLDDT 91.12
Expression Atlas ENSMUSG00000068085
MGI Symbol MGI:88603
NCBI gene (formerly Entrezgene) 545123
UniProtKB Gene Name P24457
WikiGene 545123
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 10
Ensembl ID : ENSMUSG00000094806
Gene Symbol: CYP2D10
UniProtKB Entry: A0A2R8W6W2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d10|ENSMUSG00000094806
MELLTGAGLWSVAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYS LYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQ GVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTM LNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIPGLP GKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGNAESSFNDENLRM VVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTN AVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHP EHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPRPRN LGVFPFPVAPYPYQLCAVMREQGH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8W6W2-F1 Predicted 1-176 pLDDT 88.75
AlphaFold DB AF-P24456-F1 Predicted 1-504 pLDDT 92.62
AlphaFold DB AF-A0A2R8W740-F1 Predicted 1-335 pLDDT 86.81
AlphaFold DB AF-A0A2R8VKK3-F1 Predicted 1-450 pLDDT 82.12
AlphaFold DB AF-A0A2R8VHY1-F1 Predicted 1-282 pLDDT 83.94
AlphaFold DB AF-A0A2R8W703-F1 Predicted 1-130 pLDDT 81.38
Expression Atlas ENSMUSG00000094806
MGI Symbol MGI:88602
NCBI gene (formerly Entrezgene) 13101
UniProtKB Gene Name P24456
UniProtKB Gene Name P24456
UniProtKB Gene Name P24456
UniProtKB Gene Name P24456
UniProtKB Gene Name P24456
UniProtKB Gene Name P24456
WikiGene 13101
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 9
Ensembl ID : ENSMUSG00000068086
Gene Symbol: CYP2D9
UniProtKB Entry: A0A2R8W6Y8
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d9|ENSMUSG00000068086
MELLTGTDLWPVAIFTVIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYS LYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQ GVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPM LNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLA DKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNPESSFNDENLLM VVRDLFGAGMLTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTN AVIHEVQRFGDIVPVNLPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWEKPLRFHP EHFLDAQGHFVKPEAFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSVPDGQPQPSN SGVYGILVAPSPYQLCAVVRDQGH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VHA0-F1 Predicted 1-53 pLDDT 56.69
AlphaFold DB AF-P11714-F1 Predicted 1-504 pLDDT 92.81
AlphaFold DB AF-A0A2R8W6Y8-F1 Predicted 1-254 pLDDT 86.06
AlphaFold DB AF-A0A2R8VHD8-F1 Predicted 1-158 pLDDT 78.06
AlphaFold DB AF-A0A2R8VHT2-F1 Predicted 1-208 pLDDT 74.12
AlphaFold DB AF-A0A2R8VHW1-F1 Predicted 1-294 pLDDT 86.81
AlphaFold DB AF-A0A2R8VI52-F1 Predicted 1-103 pLDDT 72.12
Expression Atlas ENSMUSG00000068086
MGI Symbol MGI:88606
NCBI gene (formerly Entrezgene) 13105
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
UniProtKB Gene Name P11714
WikiGene 13105
CYTOCHROME P450, FAMILY 4, SUBFAMILY V, POLYPEPTIDE 3
Ensembl ID : ENSMUSG00000079057
Gene Symbol: CYP4V3
UniProtKB Entry: B2RSR0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4v3|ENSMUSG00000079057
MLWLWLGLSGQKLLLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVARAYPLV GHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDK SFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKH VNQEAFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLW FDLWYLVFKEGRDHKRGLKCLHTFTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRKAFL DLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELD EVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAI IIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTI LACILRQFWVESNQKREELGLAGDLILRPNNGIWIKLKRRHEDDP

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9DBW0-F1 Predicted 1-525 pLDDT 91.25
AlphaFold DB AF-B2RSR0-F1 Predicted 1-525 pLDDT 89.88
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Visual phototransduction R-MMU-2187338
The canonical retinoid cycle in rods (twilight vision) R-MMU-2453902
Sensory Perception R-MMU-9709957
Expression Atlas ENSMUSG00000079057
MGI Symbol MGI:2142763
NCBI gene (formerly Entrezgene) 102294
UniProtKB Gene Name Q9DBW0
UniProtKB Gene Name Q9DBW0
WikiGene 102294
CYTOCHROME P450, FAMILY 26, SUBFAMILY C, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000062432
Gene Symbol: CYP26C1
UniProtKB Entry: B2RXA7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp26c1|ENSMUSG00000062432
MISWGLSCLSVLGAAGTTLLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFG ETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQS AHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQFVPRLQGALRREVRSWCAAQRPVA VYQAAKALTFRMAARILLGLQLDEARCTELAHTFEQLVENLFSLPLDVPFSGLRKGIRAR DQLYEHLDEAVAEKLQEKQTAEPGDALLLIINSARELGHEPSVQELKELAVELLFAAFFT TASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAMLG RLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSP PEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWEL ATPAFPVMQTVPIVHPVDGLLLFFHPLPTSGAGDGLPF

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B2RXA7-F1 Predicted 1-518 pLDDT 89.19
Metabolism R-MMU-1430728
Signal Transduction R-MMU-162582
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Signaling by Retinoic Acid R-MMU-5362517
RA biosynthesis pathway R-MMU-5365859
Signaling by Nuclear Receptors R-MMU-9006931
Expression Atlas ENSMUSG00000062432
MGI Symbol MGI:2679699
NCBI gene (formerly Entrezgene) 546726
UniProtKB Gene Name B2RXA7
WikiGene 546726
CYTOCHROME P450, FAMILY 26, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000024987
Gene Symbol: CYP26A1
UniProtKB Entry: A0A0R4J061
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp26a1|ENSMUSG00000024987
MGLPALLASALCTFVLPLLLFLAALKLWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQM VLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTIL GAGCLSNLHDSSHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLEQWLSCGERGLLVYPE VKRLMFRIAMRILLGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGVKAR NLIHARIEENIRAKIRRLQATEPDGGCKDALQLLIEHSWERGERLDMQALKQSSTELLFG GHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVI KETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEFNPDRFI VPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTV YPVDNLPARFTHFQGDI

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0R4J061-F1 Predicted 1-497 pLDDT 89.12
Metabolism R-MMU-1430728
Signal Transduction R-MMU-162582
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Signaling by Retinoic Acid R-MMU-5362517
RA biosynthesis pathway R-MMU-5365859
Signaling by Nuclear Receptors R-MMU-9006931
Expression Atlas ENSMUSG00000024987
MGI Symbol MGI:1096359
NCBI gene (formerly Entrezgene) 13082
UniProtKB Gene Name A0A0R4J061
WikiGene 13082
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 55
Ensembl ID : ENSMUSG00000025002
Gene Symbol: CYP2C55
UniProtKB Entry: Q9D816
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c55|ENSMUSG00000025002
MDPVLVLVLTLSCLLLLSLWRQNSGRGKLPPGPTPFPIIGNILQIDIKNISKSFNYFSKV YGPVFTLYFGSKPTVVVHGYEAVKEALDDLGEEFSGRGSFQIFERINNDLGVIFSNGTKW KELRRFSIMTLRSFGMGKRSIEDRIQEEASCLVEELRKANGSLCDPTFILSCAPSNVICS VIFHNRFDYKDEKFLNLMERLNENFKILNSPWMQVYNALPTLINYLPGSHNKVIKNFTEI KSYILGRVKEHQETLDMDNPRDFIDCFLIKMEQEKHNPHSEFTIESLMATVTDIFVAGTE TTNITLRYGLLLLLKHTEVTAKVQAEIDHVIGRHRSPCMQDRTRMPYTDAMVHEIQRYID LIPNNVPHAATCNVRFRSYFIPKGTELVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFK KSDYFMPFSIGKRMCVGEALARTELFLILTTILQNFNLKSLVDTKDIDTTPVANTFGRVP PSYQLYFIPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9D816-F1 Predicted 1-490 pLDDT 93.69
Expression Atlas ENSMUSG00000025002
MGI Symbol MGI:1919332
NCBI gene (formerly Entrezgene) 72082
UniProtKB Gene Name Q9D816
WikiGene 72082
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 65
Ensembl ID : ENSMUSG00000067231
Gene Symbol: CYP2C65
UniProtKB Entry: Q148B1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c65|ENSMUSG00000067231
MVLGVFLGLLLTCLLLLSLWRQNSQRRNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKV YGPVFTLYLGRNPAVVLHGYEAVKEAFTDHGEEFAGRGVFPVFDKFKKNCGVVFSSGRTW KEMRRFSLMTLRNFGMGRRSIEDRIQEEARCLVDELRKTKGEPCDPTFILGCAPCNVICS IVFQNRFDYKDQEFLTFLDILNENVEILSSPWIQICNNFPAVIDYLPGRHRKLHKNFAFA EHYFLSKVKQHQESLDINNPRDFIDCFLIKMEQEKHNPKTEFTCENLVFTASDLFAAGTE TTSTTLRYSLLLLLKYPEVTAKVQEEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYID LLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFPNPEKFDPSHFLDERGKFK KSDYFFPFSTGKRICVGEGLARAELFLFLTTILQNFNLKSPVDLKDLDTTPVANGFASVP PKFQICFIPI

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q148B1-F1 Predicted 1-490 pLDDT 92.5
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Expression Atlas ENSMUSG00000067231
MGI Symbol MGI:1919553
NCBI gene (formerly Entrezgene) 72303
UniProtKB Gene Name Q148B1
WikiGene 72303
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 66
Ensembl ID : ENSMUSG00000067229
Gene Symbol: CYP2C66
UniProtKB Entry: Q5GLZ0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c66|ENSMUSG00000067229
MVLGVFLGLLLTCLLLLSLWKQNSQRRNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKV YGPVFTLYLGKKPAVVLHGYKAVKEALIDHGEEFAGRGTFPVADKFIRRCGVVFSSGRTW KEMRRFSLMTLRNFGMGKRSIEDRVQEEARCLVDELRKTKGVPCDPTFILGCAPCNVICS IVFQNRFDYKDQEFLTFIDILNENVEILSSPWIQVCNNFPAIIDYLPGRHRKLLKNFDFA KHYFLAKVIQHKESLDINNPRDFIDCFLIKMEQEKHNPKTEFTCENLIFTASDLFAAGTE TTSTTLRYSLLLLLKYPEVTAKVQAEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYID LLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFLNPERFDPSHFLDESGKFK KSDYFFPFSTGKRICVGEGLARTELFLFLTTILQNFNLKSPVDLKDLDTTPVANGFVSVP PKFQICFISI

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q5GLZ0-F1 Predicted 1-490 pLDDT 93.38
AlphaFold DB AF-D6RJ25-F1 Predicted 1-68 pLDDT 76.44
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Expression Atlas ENSMUSG00000067229
MGI Symbol MGI:1917138
NCBI gene (formerly Entrezgene) 69888
UniProtKB Gene Name Q5GLZ0
UniProtKB Gene Name Q5GLZ0
WikiGene 69888
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 29
Ensembl ID : ENSMUSG00000003053
Gene Symbol: CYP2C29
UniProtKB Entry: Q3UT49
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c29|ENSMUSG00000003053
MEMETLRKVTTSCLSQPFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGS FPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKT KGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNSF PSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNPRDFIDYYLIKQKQVNHIEQ SEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCM QDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSK EFPNPEMFDPGHFLNGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLK SLVHPKEIDITPVMNGFASLPPPYQLCFIPL

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64458-F1 Predicted 1-490 pLDDT 93.19
AlphaFold DB AF-Q3UT49-F1 Predicted 1-451 pLDDT 90.5
AlphaFold DB AF-H3BLM0-F1 Predicted 1-120 pLDDT 84.31
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
Expression Atlas ENSMUSG00000003053
MGI Symbol MGI:103238
NCBI gene (formerly Entrezgene) 13095
UniProtKB Gene Name Q64458
UniProtKB Gene Name Q64458
UniProtKB Gene Name Q64458
WikiGene 13095
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 38
Ensembl ID : ENSMUSG00000032808
Gene Symbol: CYP2C38
UniProtKB Entry: P56655
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c38|ENSMUSG00000032808
MDLVTFLVLTLSSLILLSLWRQRSRRGRLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKT YGPVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSW KETRRFTLMTLRNLGMGKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICS IIFQDRFDYKDKDFLMLMKKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNFKYI RSYLLEKVKEHQESLDVTNPRDFIDYFLIKQKQANHIEQAEYSLENLVCTINNLFAAGTE TTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFIN LVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGNFK KSDYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLKSLVHPKDIDMIPFVNGLITLP PHYQLCFIPL

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P56655-F1 Predicted 1-490 pLDDT 93.62
Expression Atlas ENSMUSG00000032808
MGI Symbol MGI:1306819
NCBI gene (formerly Entrezgene) 13097
UniProtKB Gene Name P56655
WikiGene 13097
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 39
Ensembl ID : ENSMUSG00000025003
Gene Symbol: CYP2C39
UniProtKB Entry: P56656
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c39|ENSMUSG00000025003
MDLVTFLVLTLSSLILLSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKA YGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRW KEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICS IIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYI RSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTE TTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFIN LVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNFK KSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALP PHYQVCIIPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P56656-F1 Predicted 1-490 pLDDT 93.19
Expression Atlas ENSMUSG00000025003
MGI Symbol MGI:1306818
NCBI gene (formerly Entrezgene) 13098
UniProtKB Gene Name P56656
WikiGene 13098
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 67
Ensembl ID : ENSMUSG00000062624
Gene Symbol: CYP2C67
UniProtKB Entry: Q569X9
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c67|ENSMUSG00000062624
MDPFVVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKT YGPVFTLYFGSQPIVVLHGYEAMKEAFIDHGEEFSGRGRFPFFDKVTKGKGIGFSHGNVW KATRVFTINTLRNLGMGKRTIENKVQEEAQWLMKELKKTNGLPCDPQFIIGCAPCNVICS IVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWI KSYLLEKIKEHEESLDVTNPRDFIDYFLIQRCQEKGIEHMEYTIEHLATLVTDLVFGGTE SLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYVD LGPISLVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFK KSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIP PNFQMCFIPVE

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q569X9-F1 Predicted 1-491 pLDDT 93.06
Expression Atlas ENSMUSG00000062624
MGI Symbol MGI:3612288
NCBI gene (formerly Entrezgene) 545288
UniProtKB Gene Name Q569X9
WikiGene 545288
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 68
Ensembl ID : ENSMUSG00000074882
Gene Symbol: CYP2C68
UniProtKB Entry: K7N6C2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c68|ENSMUSG00000074882
MDPFVVLVLCLSFLLLLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKI YGPVFTLYFGSQPIVILHGYEAMKEAFIDYGEEFSGRGRIPVFDKVSKGKGIGFSHGNVW KATRVFTVNTLRNLGMGKRTIETKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICS IVFQNRFDYKDKDFLSLIGKVNECTEILSSPECQIFNAVPILIDYCPGSHNKFLKNHTWI KSYLLEKIKEHEESLDVTNPRDFVDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTE TLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYID LGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFK KSDYFMPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIP PNFQMCFIPVE

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-K7N6C2-F1 Predicted 1-491 pLDDT 93.25
Expression Atlas ENSMUSG00000074882
MGI Symbol MGI:3612287
NCBI gene (formerly Entrezgene) 433247
UniProtKB Gene Name K7N6C2
WikiGene 433247
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 40
Ensembl ID : ENSMUSG00000025004
Gene Symbol: CYP2C40
UniProtKB Entry: E9Q7C8
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c40|ENSMUSG00000025004
MPKRKILICECCIKCLECLIIPVSVRRVSMDPFVVLVLCLSFLLVLSLWRQRSARGNLPP GPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHG EEFSGRGRIPVFDKVSTGKGIGFSHGNVWKATRVFTVNTLRNLGMGKRTIENKVQEEAQW LMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSP GCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTNPRDFIDYFLIQR RQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVI GRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSL TSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTT ILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E0CXY8-F1 Predicted 1-120 pLDDT 82.94
AlphaFold DB AF-E9Q7C8-F1 Predicted 1-520 pLDDT 89.44
AlphaFold DB AF-P56657-F1 Predicted 1-491 pLDDT 93.06
AlphaFold DB AF-E0CYU2-F1 Predicted 1-165 pLDDT 91.12
Expression Atlas ENSMUSG00000025004
MGI Symbol MGI:1306815
NCBI gene (formerly Entrezgene) 13099
UniProtKB Gene Name P56657
UniProtKB Gene Name P56657
UniProtKB Gene Name P56657
UniProtKB Gene Name P56657
WikiGene 13099
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 69
Ensembl ID : ENSMUSG00000092008
Gene Symbol: CYP2C69
UniProtKB Entry: A0A494B9A4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c69|ENSMUSG00000092008
MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKT YGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVW KATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICS IVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWI KSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTE TLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVD LGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFK KSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIP PKFQMCFIPVE

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9PXC3-F1 Predicted 1-491 pLDDT 93.0
AlphaFold DB AF-A0A494B9A4-F1 Predicted 1-165 pLDDT 90.69
Expression Atlas ENSMUSG00000092008
MGI Symbol MGI:3721049
NCBI gene (formerly Entrezgene) 100043108
UniProtKB Gene Name E9PXC3
UniProtKB Gene Name E9PXC3
WikiGene 100043108
CYTOCHROME P450, FAMILY 2. SUBFAMILY C, POLYPEPTIDE 37
Ensembl ID : ENSMUSG00000042248
Gene Symbol: CYP2C37
UniProtKB Entry: P56654
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c37|ENSMUSG00000042248
MDPILVLVLTLSCLFLLSLWRQSSERGKLPPGPTPLPIIGNILQIDVKDICQSFTNLSKV YGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRFPVFDKATNGMGLAFSKGNVW KNTRRFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICS IIFQDRFDYKDRDFLNLMEKLNEITKILSSPWLQICNTYPALLDYCPGSHKQFFKNYASI KNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQEDGNQPLQNRLEHLAITVTDLFSAGTE TTSTTLRYAILLLLKYPHVTAKVQEEIEHVIGKHRSPCMQDRSRMPYTDAMIHEVQRFID LIPNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGKFK KSDYFIPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDVTPMLIGLASVP PAFQLCFIPS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P56654-F1 Predicted 1-490 pLDDT 94.06
Expression Atlas ENSMUSG00000042248
MGI Symbol MGI:1306806
NCBI gene (formerly Entrezgene) 13096
UniProtKB Gene Name P56654
WikiGene 13096
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 54
Ensembl ID : ENSMUSG00000067225
Gene Symbol: CYP2C54
UniProtKB Entry: Q6XVG2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c54|ENSMUSG00000067225
MDPILVLVLTLSCLFLLSLWRQSYERGKLPPGPTPLPIIGNILQIDVKDICQSFTNLSRV YGPVYTLYLGRKPTVVLHGYEAVKEALVDHGDVFAGRGRLPVFDKATNGMGIGFSNGSVW KNTRHFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICS IIFQDRFDYKDRDFLNLLEKLDEISKILSTPWLQVCNTFPALLDYCPGSHNQFFKNYAYI KNFLLEKIREHKESLDVTIPRDFIDYFLIKGAQEDDNHPLKNNFEHLAITVTDLFIGGTE SMSTTLRYALLLLLKYPHVTAKVQEEIEHVIGKHRRPCMQDRSHMPYTNAMIHEVQRFID LVPNNLPHEVTCDIKFRNYFIPKGTTVITSLSSVLRDSKEFPNPEKFDPGHFLDENGKFK KSDYFMPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDITPMLIGLGSVP PAFQLCFIPS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q6XVG2-F1 Predicted 1-490 pLDDT 94.44
Expression Atlas ENSMUSG00000067225
MGI Symbol MGI:3642960
NCBI gene (formerly Entrezgene) 404195
UniProtKB Gene Name Q6XVG2
WikiGene 404195
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 50
Ensembl ID : ENSMUSG00000054827
Gene Symbol: CYP2C50
UniProtKB Entry: Q91X77
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c50|ENSMUSG00000054827
MDPILVLVFTLSCLFLLSLWRQSSERGKLPPGPTPLPIIGNILQINVKDICQSFTNLSKV YGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRLPVFDKATNGMGIIFSKGNVW KNTRRFSLTTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICS IIFQDRFDYKDRDFLNLMEKLNEITKIMSTPWLQVCNTFPVLLDYCPGSHNKVFKNYACI KNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQENGNYPLKNRLEHLAITVTDLFSAGTE TTSTTLRYALLLLLKYPHVTAKVQEEIEHVIGKHRRPCMQDRSHMPYTDAMIHEVQRFID LVPNSLPHEVTCDIKFRNYFIPKGTNVITSLSSVLRDSKEFPNPEKFDPGHFLDENGKFK KSDYFMPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDVTPMLIGLASVP PAFQLCFIPS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q91X77-F1 Predicted 1-490 pLDDT 93.38
Expression Atlas ENSMUSG00000054827
MGI Symbol MGI:2147497
NCBI gene (formerly Entrezgene) 107141
UniProtKB Gene Name Q91X77
WikiGene 107141
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 70
Ensembl ID : ENSMUSG00000060613
Gene Symbol: CYP2C70
UniProtKB Entry: E9Q8U5
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c70|ENSMUSG00000060613
MALFIFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKSMGMLAKK YGPVFTVYLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGIVFSNGETW KQTRRFSLMVLRSMGMGKKTIEDRIQEEILYMLDALRKTNGSPCDPSFLLACVPCNVIST VIFQHRFDYNDQTFQDFMENFHRKIEILASPWSQLCSAYPILYYLPGIHNRFLKDVTQQK KFILEEINRHQKSLDLSNPQDFIDYFLIKMEKEKHNQKSEFTMDNLVVSIGDLFGAGTET TSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRRPTMQDRNHMPYTDAVLHEIQRYIDF VPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKK SDYFVAFSAGRRACIGEGLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVPP PFELCFIPV

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q91W64-F1 Predicted 1-489 pLDDT 93.69
AlphaFold DB AF-E9Q2L0-F1 Predicted 1-76 pLDDT 70.69
AlphaFold DB AF-E9Q8U5-F1 Predicted 1-72 pLDDT 70.5
Expression Atlas ENSMUSG00000060613
MGI Symbol MGI:2385878
NCBI gene (formerly Entrezgene) 226105
UniProtKB Gene Name Q91W64
UniProtKB Gene Name Q91W64
UniProtKB Gene Name Q91W64
WikiGene 226105
CYTOCHROME P450, FAMILY 2, SUBFAMILY S, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000040703
Gene Symbol: CYP2S1
UniProtKB Entry: D3Z7F1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2s1|ENSMUSG00000040703
MEAASTWALLLALLLLLLLLSLTLFRTPARGYLPPGPTPLPLLGNLLQLRPGALYSGLLR LSKKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKTFDGHGVFFA NGERWKQLRKFTLLALRDLGMGKREGEELIQAEVQSLVEAFQKTEGRPFNPSMLLAQATS NVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQH HLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQEKQDPGTEFTEKNLLMTVTYL LFAGTMTIGATIRYALLLLLRYPQVQQRVREELIQELGPGRAPSLSDRVRLPYTDAVLHE AQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLD EDGRLRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLETPCPPGDLSLKPAIS GLFNIPPDFQLRVWPTGDQSR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9DBX6-F1 Predicted 1-501 pLDDT 93.12
AlphaFold DB AF-D3Z7F1-F1 Predicted 1-448 pLDDT 90.06
AlphaFold DB AF-D3Z762-F1 Predicted 1-90 pLDDT 91.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000040703
MGI Symbol MGI:1921384
NCBI gene (formerly Entrezgene) 74134
UniProtKB Gene Name Q9DBX6
UniProtKB Gene Name Q9DBX6
UniProtKB Gene Name Q9DBX6
WikiGene 74134
CYTOCHROME P450, FAMILY 2, SUBFAMILY B, POLYPEPTIDE 10
Ensembl ID : ENSMUSG00000030483
Gene Symbol: CYP2B10
UniProtKB Entry: Q9WUD0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2b10|ENSMUSG00000030483
MEPSVLLLLALLVGFLLLLARGHPKSRGNFPPGPRPLPLLGNLLQMDRGGLLKSFIQLRE KYGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYGVIFANGER WKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIIC SIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYFPGAHRQISKNLQE LLDYIGHSVEKHRATLDPSVPRDFIDIYLLRMEKEKSNQHTEFHHQNLMMSVLSLFFAGT ETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFS DLIPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGAL KKSEAFLPFSTGQIFDQKSVGKRICLGESIARNELFLFFTSILQNFSVASHVAPKDIDLT PKESGIGKIPPTYQICFLAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-G3X8Q9-F1 Predicted 1-500 pLDDT 92.38
AlphaFold DB AF-Q9WUD0-F1 Predicted 1-491 pLDDT 93.56
Expression Atlas ENSMUSG00000030483
MGI Symbol MGI:88598
NCBI gene (formerly Entrezgene) 13088
UniProtKB Gene Name Q9WUD0
UniProtKB Gene Name Q9WUD0
WikiGene 13088
CYTOCHROME P450, FAMILY 2, SUBFAMILY B, POLYPEPTIDE 13
Ensembl ID : ENSMUSG00000040583
Gene Symbol: CYP2B13
UniProtKB Entry: A6H6J2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2b13|ENSMUSG00000040583
MDPSVLLLLAVLLSLFLLLVRGHAKIHGHLPPGPRPLPLLGNLLQMDRGGLLKCFIHLQE KHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYGIFFSSGER WKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGAPLDPTFFFQCVTANIIC SIVFGERFDYTDEQFLRLLNLMYQIYSLLRSFSCQMFELFSGLLKYFPGVHRQIAKNQQE ILNFITHRVEKHRATLDPSEPRDFIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGT ETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFS DIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGAL KKSEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSVASPVASKDIDLTPKESGIGKI PPTYQICFLAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A6H6J2-F1 Predicted 1-491 pLDDT 92.38
Expression Atlas ENSMUSG00000040583
MGI Symbol MGI:88599
NCBI gene (formerly Entrezgene) 13089
UniProtKB Gene Name A6H6J2
WikiGene 13089
CYTOCHROME P450, FAMILY 2, SUBFAMILY B, POLYPEPTIDE 9
Ensembl ID : ENSMUSG00000040660
Gene Symbol: CYP2B9
UniProtKB Entry: P12790
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2b9|ENSMUSG00000040660
MDPSVLLLLAVLLSLFLLLVRGHAKIHGHLPPGPHPLPLLGNLLQMDRGGLLKCFIQLQE KHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQR WKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIIC SIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVKKQQE LLDYIAHSVEKHKATLDPSAPRDYIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGT ETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFS DLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLDANGAL KKCEAFLPFSTGKRICLGESIARNELFIFFTTILQNFSVASPVAPKDIDLTPKESGIGKI PPAHQIYFLAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P12790-F1 Predicted 1-491 pLDDT 93.38
Expression Atlas ENSMUSG00000040660
MGI Symbol MGI:88600
NCBI gene (formerly Entrezgene) 13094
UniProtKB Gene Name P12790
WikiGene 13094
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 4
Ensembl ID : ENSMUSG00000074254
Gene Symbol: CYP2A4
UniProtKB Entry: P15392
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2a4|ENSMUSG00000074254
MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNSLMK ISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLFKGYGIAFSS GERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSN VISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKE LQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFF AGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQ RFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDK GQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQEPQDIDVSPRLVGF VTIPPTYTMSFLSR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P15392-F1 Predicted 1-494 pLDDT 96.0
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000074254
MGI Symbol MGI:88596
NCBI gene (formerly Entrezgene) 13086
UniProtKB Gene Name P15392
WikiGene 13086
CYTOCHROME P450, FAMILY 2, SUBFAMILY B, POLYPEPTIDE 23
Ensembl ID : ENSMUSG00000040650
Gene Symbol: CYP2B23
UniProtKB Entry: E9Q593
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2b23|ENSMUSG00000040650
MEPSVLLLLALLTGFLLLLIRGQPKAYSRLPPGPRPLPFLGNLLQMDRGGLLKSFIKLRD KHGDVFTVHLGPRPVVMLYGTETIKEALVDHSDAFSGRGAIAVIQPIVQDYGVIFSSGER WKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYEGAPLDPTFLFQCITANIIC SIVFGERFDYTDHQFLHLLDLFYQTLSLISSFSSQLFELFSAVLKYFPGTHRQISKNIQE ILNYIGHSVEQHKATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHQNLLISVLSLFFAGT ETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVISAHHVPTLEDRIKMPYTEAVIHEIQRFS DLAPIGLPHTVTKDTVFRGYLLPKNTEVYPILSSALHDPQYFEQPDKFNPEHFLDANGAL KKSEAFLPFSTGKRICLGEGIARNELFLFFTALLQNFSLSSPVAPEDIDLTPKESGFVKI PPVYRICFLPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q593-F1 Predicted 1-491 pLDDT 93.38
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000040650
MGI Symbol MGI:3646735
NCBI gene (formerly Entrezgene) 243881
UniProtKB Gene Name E9Q593
WikiGene 243881
CYTOCHROME P450, FAMILY 2, SUBFAMILY B, POLYPEPTIDE 19
Ensembl ID : ENSMUSG00000066704
Gene Symbol: CYP2B19
UniProtKB Entry: O55071
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2b19|ENSMUSG00000066704
MEFSVLLLLALTTGFLIFLVSQSQPKTHGHFPPGPRPLPFLGNLLQMDRRGLLSSFIQLQ EKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGE RWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANII CSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFPGAHRQISKNLQ EILDYIGHSVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFAG TETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRF TDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLDANGA LKTNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLASPVAPENIDLIPNNSGATK TPPQYQIHFLSR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O55071-F1 Predicted 1-492 pLDDT 92.75
Expression Atlas ENSMUSG00000066704
MGI Symbol MGI:107303
NCBI gene (formerly Entrezgene) 13090
UniProtKB Gene Name O55071
WikiGene 13090
CYTOCHROME P450, FAMILY 2, SUBFAMILY G, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000049685
Gene Symbol: CYP2G1
UniProtKB Entry: Q9WV19
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2g1|ENSMUSG00000049685
MMLGGAFSIFMALCLSCLLILIAWKRTSKGGKLPPGPTPIPFLGNFLQVRTDATFQSFQK LQKKYGSVFTVYFGPRPVVVLCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSN GERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTLYLSRTVSN VICSVVFGKRFDYQDQRFQSLMRMINESFVEMSKPWAQLYDMYWKVMQYFPGRHNYLYNL IEDLKDFIASRVKINEASFDPSNPRDFIDCFLIKMHQDKSDPHTEFNLKNLVLTTLNLFF AGTETVSSTLRYGFLLLLKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQ RLTDIVPLGVPHNVTRDTHFRGYLLPKGTDVYPLFGSVLKDPKYFRYPDAFYPQHFLDEQ GRFKKNDAFVVFSSGKRICVGEALARMELFLYFTSILQRFSLRSLVPPADIDIAHKISGF GNIPPVYELCFMAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9WV19-F1 Predicted 1-494 pLDDT 94.44
Expression Atlas ENSMUSG00000049685
MGI Symbol MGI:109612
NCBI gene (formerly Entrezgene) 13108
UniProtKB Gene Name Q9WV19
WikiGene 13108
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 5
Ensembl ID : ENSMUSG00000005547
Gene Symbol: CYP2A5
UniProtKB Entry: Q91X75
Assay organism Assay description Assay tissue Bioactivities Reference
AMPHETAMINE
Inhibitory concentration against mouse cytochrome P450 2A5 — IC50 = 2850.0 nM
NICOTINE
Inhibition of mouse CYP2A5 — IC50 = 159955.8 nM
COUMARIN
Michaelis-Menten constant of compound against mouse cytochrome P450 2A5 enzyme — Km = 640.0 nM
COTININE
Inhibitory concentration against mouse cytochrome P450 2A5 — IC50 = 1500000.0 nM
NAPHTHALENE
Inhibition of mouse CYP2A5 — IC50 = 73960.53 nM
NAPHTHALENE
Inhibitory concentration against mouse cytochrome P450 2A5 — IC50 = 74000.0 nM
PHENANTHRENE
Inhibition of mouse CYP2A5 — IC50 = 26001.6 nM
PHENANTHRENE
Inhibitory concentration against mouse cytochrome P450 2A5 — IC50 = 26000.0 nM

>Cyp2a5|ENSMUSG00000005547
MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNFLQLNTEQMYNSLMK ISQRYGPVFTIYLGPRRIVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSS GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSN VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPGPQQQAFKE LQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFF AGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQ RFADMIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDK GQFKKNDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVGF ATIPPTYTMSFLSR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-F7B9W9-F1 Predicted 1-128 pLDDT 84.62
AlphaFold DB AF-E9Q5D4-F1 Predicted 1-61 pLDDT 77.06
AlphaFold DB AF-Q91X75-F1 Predicted 1-494 pLDDT 96.06
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Aflatoxin activation and detoxification R-MMU-5423646
Expression Atlas ENSMUSG00000005547
MGI Symbol MGI:88597
NCBI gene (formerly Entrezgene) 13087
UniProtKB Gene Name Q91X75
UniProtKB Gene Name Q91X75
UniProtKB Gene Name Q91X75
WikiGene 13087
CYTOCHROME P450, FAMILY 19, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000032274
Gene Symbol: CYP19A1
UniProtKB Entry: Q3ZAT3
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp19a1|ENSMUSG00000032274
MFLEMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSSSIPGPGYCLGIGPLI SHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHYISRFGSKR GLQCIGMHENGIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTD TSGYVDVLTLMRHIMLDTSNMLFLGIPLDESAIVKKIQGYFNAWQALLIKPNIFFKISWL YRKYERSVKDLKDEIAVLVEKKRHKVSTAEKLEDCMDFATDLIFAERRGDLTKENVNQCI LEMLIAAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVGDRDIKIEDIQNLKVVENFI NESMRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILNIGRMHRLEYFPKPNEFTLENFEK NVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKKNDLSLH PNEDRHLVEIIFSPRNSDKYLQQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P28649-F1 Predicted 1-503 pLDDT 91.06
AlphaFold DB AF-Q3ZAT3-F1 Predicted 1-503 pLDDT 90.81
AlphaFold DB AF-A0A1L1SUD6-F1 Predicted 1-436 pLDDT 94.69
Metabolism R-MMU-1430728
Estrogen biosynthesis R-MMU-193144
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000032274
MGI Symbol MGI:88587
NCBI gene (formerly Entrezgene) 13075
UniProtKB Gene Name Q3ZAT3
UniProtKB Gene Name Q3ZAT3
UniProtKB Gene Name Q3ZAT3
WikiGene 13075
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 22
Ensembl ID : ENSMUSG00000091867
Gene Symbol: CYP2A22
UniProtKB Entry: B2RXZ2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2a22|ENSMUSG00000091867
MLGSGLLLVAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQL QEHYGPVFTIHLGPRRVVVLYGYDAVKEALEDNAEEFSGRGEQATFNTLFKGYGVTFSNG ERAKQLRRFSIATLKDFGLGKRGMEERIQEEAGCLIKMLQGTCGAPIDPTMYLSKTVSNV ISSIVFGDRFNYEDKEFLSLLQMMSQMNQFAASPTGQLYDMFHSVMKYLPGPQQQIIKDS HKLEDFMIQKVKHNHSTLDPNSPRGFIDSFLIHMQKEKNFNSEFHMKNLVMTSLNLFFAG SETVSSLLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVIHEIQRF SNFAPLGIPRRITKDTSFRGFFLPKGTDVFPIMGSLMIDPKFFSSPKDFNPQHFLDDKGQ LKKIPAFLPFSIGKRSCLGYSLGKMQLFLFFTTILQNFRFKFPRKLEDINESPKPEGFTR IIPKYTMSFVPI

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B2RXZ2-F1 Predicted 1-492 pLDDT 92.5
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000091867
MGI Symbol MGI:3648316
NCBI gene (formerly Entrezgene) 233005
UniProtKB Gene Name B2RXZ2
WikiGene 233005
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 12
Ensembl ID : ENSMUSG00000060407
Gene Symbol: CYP2A12
UniProtKB Entry: P56593
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2a12|ENSMUSG00000060407
MLGSGLLLLAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQL QEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKGYGVAFSNG ERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNV ISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGPQQQIIKDS HKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLNLFFAG SETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRF SNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQ LKKIPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKLEDINESPTPEGFTR IIPKYTMSFVPI

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P56593-F1 Predicted 1-492 pLDDT 92.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000060407
MGI Symbol MGI:105055
NCBI gene (formerly Entrezgene) 13085
UniProtKB Gene Name P56593
WikiGene 13085
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 57
Ensembl ID : ENSMUSG00000070419
Gene Symbol: CYP3A57
UniProtKB Entry: G3UX95
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a57|ENSMUSG00000070419
MELIPNLSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWKF DDDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKSITI SEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYS MDVITGTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSI FPRQSMNFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTL IFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVV NESLRLYPVVSRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFS KENKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQ PIFRPEKPIILKFVSRDKPRTGP

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-D3YYZ0-F1 Predicted 1-503 pLDDT 91.62
AlphaFold DB AF-G3UX95-F1 Predicted 1-149 pLDDT 92.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000070419
MGI Symbol MGI:3646373
NCBI gene (formerly Entrezgene) 622127
UniProtKB Gene Name G3UX95
UniProtKB Gene Name G3UX95
WikiGene 622127
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 16
Ensembl ID : ENSMUSG00000038656
Gene Symbol: CYP3A16
UniProtKB Entry: Q64481
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a16|ENSMUSG00000038656
MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKF DMECYEKYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISL AKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYS MDVIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICM FPKDSIEFFKKFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQS IIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMV LNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERF SKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSR ELLLQPVKPIVLKVVPRDAVITGA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64481-F1 Predicted 1-504 pLDDT 90.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000038656
MGI Symbol MGI:106099
NCBI gene (formerly Entrezgene) 13114
UniProtKB Gene Name Q64481
WikiGene 13114
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 41B
Ensembl ID : ENSMUSG00000075552
Gene Symbol: CYP3A41B
UniProtKB Entry: Q9JMA7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a41b|ENSMUSG00000075552
MNLFSALSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKF DMECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISI SKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYS IDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICM FPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQS IVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMV LNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERF SKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSR QGLLQPEKPIVLKVVPRDVVITGA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9JMA7-F1 Predicted 1-504 pLDDT 90.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000075552
MGI Symbol MGI:3714859
NCBI gene (formerly Entrezgene) 100041375
UniProtKB Gene Name Q9JMA7
WikiGene 100041375
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 41A
Ensembl ID : ENSMUSG00000075551
Gene Symbol: CYP3A41A
UniProtKB Entry: Q9JMA7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a41a|ENSMUSG00000075551
MNLFSALSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKF DMECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISI SKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYS IDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICM FPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQS IVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMV LNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERF SKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSR QGLLQPEKPIVLKVVPRDVVITGA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9JMA7-F1 Predicted 1-504 pLDDT 90.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000075551
MGI Symbol MGI:1858451
NCBI gene (formerly Entrezgene) 53973
UniProtKB Gene Name Q9JMA7
WikiGene 53973
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 44
Ensembl ID : ENSMUSG00000054417
Gene Symbol: CYP3A44
UniProtKB Entry: Q9EQW4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a44|ENSMUSG00000054417
MNLFSALSLDTLVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYTGIWKF DMECYEKYGKTWGLFDGQTPLLVITDPETIKNVLVKDCLSVFTNRREFGPVGIMSKAISI SKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMPVAMKDVLGAYS MDVITSTSFGVNVDSLNNPEDPFVEEAKKFLRVDFFDPLLFSVVLFPLLTPVYEMLNICM FPNDSIEFFKKFVDRMQESRLDSNQKHRVDFLQLMMNSHNNSKDKDSHKAFSNMEITVQS IIFISAGYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPNKATPTCDTVMEMEYLDMV LNETLRLYPIVTRLERVCKKDVELNGVYIPKGSMVMIPSYALHHDPQHWPDPEEFQPERF SKENKGSIDPYVYLPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIPLKLSR QGILQPEKPIVLKVVPRDAVITGA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9EQW4-F1 Predicted 1-504 pLDDT 91.31
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000054417
MGI Symbol MGI:2449818
NCBI gene (formerly Entrezgene) 337924
UniProtKB Gene Name Q9EQW4
WikiGene 337924
CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 23
Ensembl ID : ENSMUSG00000025197
Gene Symbol: CYP2C23
UniProtKB Entry: E9Q5K4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2c23|ENSMUSG00000025197
MELLGLPTLALLVLVMSLSLLSVWTKMRTGGRLPPGPTPLPIIGNILQLDLKDIPASLSK LAKEYGPVYTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSE GERWKLLRRFSLMTLKNFGMGKRSLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCN VICSILFNERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKR LGGVKNFILEKVKEHQESLDPANPRDYIDCFLSKIEEEKHNLKSDFNLENLAICGSNLFT AGTETTSTTLRFGLLLLVKHPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQ RYITLLPSSLPHAVVQDTKFRHYVIPKGTAVFPFLSSILLDQKEFPNPEKFDPGHFLDKN GCFKKTDYFVPFSLGKRSCVGEGLARMELFLFFTTILQKFSLKALVEPKDLDIKPVTTGL FNLPPPYKLRLVPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q5K4-F1 Predicted 1-494 pLDDT 92.06
Expression Atlas ENSMUSG00000025197
MGI Symbol MGI:1888897
NCBI gene (formerly Entrezgene) 226143
UniProtKB Gene Name E9Q5K4
WikiGene 226143
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 11
Ensembl ID : ENSMUSG00000056035
Gene Symbol: CYP3A11
UniProtKB Entry: Q3UEN8
Assay organism Assay description Assay tissue Bioactivities Reference
CANNABIDIOL
Mechanism based inhibition of mouse cytochrome P450 CYP3A11 — mechanism based inhibition None None None

>Cyp3a11|ENSMUSG00000056035
MDLVSALSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKF DMECYKKYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISI SKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYS MDVITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICM FPKDSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQS IIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMV LNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERF SKENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSR QGLLQPEKPIVLKVVPRDAVITGA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3UEN8-F1 Predicted 1-504 pLDDT 90.38
AlphaFold DB AF-Q64459-F1 Predicted 1-504 pLDDT 90.88
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000056035
MGI Symbol MGI:88609
NCBI gene (formerly Entrezgene) 13112
UniProtKB Gene Name Q64459
UniProtKB Gene Name Q64459
WikiGene 13112
CYTOCHROME P450, FAMILY 27, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000006724
Gene Symbol: CYP27B1
UniProtKB Entry: E9Q3C2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp27b1|ENSMUSG00000006724
MTQAVKLASRVFHRIHLPLQLDASLGSRGSESVLRSLSDIPGPSTLSFLAELFCKGGLSR LHELQVHGAARYGPIWSGSFGTLRTVYVADPTLVEQLLRQESHCPERCSFSSWAEHRRRH QRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRRLRRQRGRGSGLP GLVLDVAGEFYKFGLESIGAVLLGSRLGCLEAEVPPDTETFIHAVGSVFVSTLLTMAMPN WLHHLIPGPWARLCRDWDQMFAFAQRHVELREGEAAMRNQGKPEEDMPSGHHLTHFLFRE KVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEITAGTRGSCAHPHG TALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDIRVGNYVIPQDTLVSLCHYATSRDPTQ FPDPNSFNPARWLGEGPTPHPFASLPFGFGKRSCIGRRLAELELQMALSQILTHFEVLPE PGALPIKPMTRTVLVPERSINLQFVDR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q3C2-F1 Predicted 1-135 pLDDT 42.06
AlphaFold DB AF-O35084-F1 Predicted 1-507 pLDDT 86.56
Metabolism R-MMU-1430728
Vitamin D (calciferol) metabolism R-MMU-196791
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000006724
MGI Symbol MGI:1098274
NCBI gene (formerly Entrezgene) 13115
UniProtKB Gene Name O35084
UniProtKB Gene Name O35084
WikiGene 13115
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 25
Ensembl ID : ENSMUSG00000029630
Gene Symbol: CYP3A25
UniProtKB Entry: D3Z707
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a25|ENSMUSG00000029630
MELIPNLSIETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTIFNYYDGMWKF DEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITI SEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYS MDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSI FPRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVV NESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFS KENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISRE PIFQPEKPIILKVVSRDKPRTGS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O09158-F1 Predicted 1-503 pLDDT 91.56
AlphaFold DB AF-D3Z707-F1 Predicted 1-137 pLDDT 77.62
AlphaFold DB AF-D6RJM4-F1 Predicted 1-149 pLDDT 91.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000029630
MGI Symbol MGI:1930638
NCBI gene (formerly Entrezgene) 56388
UniProtKB Gene Name O09158
UniProtKB Gene Name O09158
UniProtKB Gene Name O09158
WikiGene 56388
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 59
Ensembl ID : ENSMUSG00000061292
Gene Symbol: CYP3A59
UniProtKB Entry: D3Z2W7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a59|ENSMUSG00000061292
MELIPNLSIETWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGTIFNYFDGMWKF DEDCYKKYGKIWGFYVGPKPILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFLKKSITI SEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYS MDVITGTSFGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIYEMLNLSI FPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVV NESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFS KENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISRE PVFQPEKPIILKVVSRDKPRTAS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0G2JE14-F1 Predicted 1-149 pLDDT 90.62
AlphaFold DB AF-D3Z2W7-F1 Predicted 1-503 pLDDT 92.06
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000061292
MGI Symbol MGI:3769707
NCBI gene (formerly Entrezgene) 100041449
UniProtKB Gene Name D3Z2W7
UniProtKB Gene Name D3Z2W7
WikiGene 100041449
CYTOCHROME P450, FAMILY 17, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000003555
Gene Symbol: CYP17A1
UniProtKB Entry: Q53YJ1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp17a1|ENSMUSG00000003555
MWELVGLLLLILAYFFWPKSKTPNAKFPRSLPFLPLVGSLPFLPRRGHMHANFFKLQEKY GPIYSLRLGTTTAVIVGHYQLAREVLVKKGKEFSGRPQMVTLGLLSDQGKGVAFADSSSS WQLHRKLVFSTFSLFRDDQKLEKMICQEANSLCDLILTYDGESRDLSTLIFKSVINIICT ICFNISFENKDPILTTIQTFTEGIVDVLGHSDLVDIFPWLKIFPNKNLEMIKEHTKIREK TLVEMFEKCKEKFNSESLSSLTDILIQAKMNAENNNTGEGQDPSVFSDKHILVTVGDIFG AGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVL RIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDRFMPERFLDPT GSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPK VVFLIDPFKVKITVRQAWKDAQVEVST

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A494B9N2-F1 Predicted 1-455 pLDDT 84.88
AlphaFold DB AF-Q53YJ1-F1 Predicted 1-507 pLDDT 92.12
AlphaFold DB AF-P27786-F1 Predicted 1-507 pLDDT 92.69
Metabolism R-MMU-1430728
Androgen biosynthesis R-MMU-193048
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000003555
MGI Symbol MGI:88586
NCBI gene (formerly Entrezgene) 13074
UniProtKB Gene Name Q53YJ1
UniProtKB Gene Name Q53YJ1
UniProtKB Gene Name Q53YJ1
WikiGene 13074
CYTOCHROME P450, FAMILY 2, SUBFAMILY U, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000027983
Gene Symbol: CYP2U1
UniProtKB Entry: Q9CX98
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2u1|ENSMUSG00000027983
MSSLGDQRPAAGEQPGARLHVRATGGALLLCLLAVLLGWVWLRRQRACGIPPGPKPRPLV GNFGHLLVPRFLRPQFWLGSGSQTDTVGQHVYLARMARVYGNIFSFFIGHRLVVVLSDFH SVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLS LEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDF MSRGLEICLHSQLFLINICPWFYYLPFGPFKELRQIERDISCFLKNIIREHQESLDASNP QDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDV QKKVHEEIERVIGCDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGF TIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQ LAKMELFLMFVSLMQTFTFALPEGSEKPVMTGRFGLTLAPHPFNVTISKR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9CX98-F1 Predicted 1-530 pLDDT 88.44
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000027983
MGI Symbol MGI:1918769
NCBI gene (formerly Entrezgene) 71519
UniProtKB Gene Name Q9CX98
WikiGene 71519
CYTOCHROME P450, FAMILY 4, SUBFAMILY X, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000047155
Gene Symbol: CYP4X1
UniProtKB Entry: Q6A152
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4x1|ENSMUSG00000047155
MEASWLETRWARPLHLALVFCLALVLMQAMKLYLRRQRLLRDLSPFPGPPAHWLLGHQKF LQEDNMETLDEIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTPC IGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEV FEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKL SPKGHCFQELGKVIHQYTEKIIQDRKKILKNQVKQDDTQTSQIFLDIVLSAQAEDERAFS DADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLD EMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWND PKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLT RPPAFSSHTVLRPKHGIYLHLKKLLEC

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q6A152-F1 Predicted 1-507 pLDDT 91.0
AlphaFold DB AF-A2A9Y7-F1 Predicted 1-481 pLDDT 91.06
Expression Atlas ENSMUSG00000047155
MGI Symbol MGI:1932403
NCBI gene (formerly Entrezgene) 81906
UniProtKB Gene Name Q6A152
UniProtKB Gene Name Q6A152
WikiGene 81906
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 29
Ensembl ID : ENSMUSG00000083138
Gene Symbol: CYP4A29
UniProtKB Entry: A0A087WPC3
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a29|ENSMUSG00000083138
MSISALSPIRFLECVSGFLQVIFLIGLLLLLFKAAQHYLRRQWLLRALYQFPSPPSHWLF GHCLQFKVDEELRWILRYLEKFPGAFLHWIWGSHVFIKVCDPDYMKVILGRADPKASLYR FLTPWLGHGLFFLNGDEWFQHRRLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDI TLEIFHPISLMMLDTIMKYAFSYQGSVQLDRSSQAYLQAVSDLNNLVTSRMKNVFLHNDI IYNLTSHSRRTNSACQIAHEHTDRVVKLRKAQLQDNKSMKKLRGKRCLDFLDILLLSRMD DGSSLSDKALRAEVDSLMFGGHDTPASGISWVFYALATHPDHQQRCREEVQSLLGDGSPI TWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPVTFPDGRSLPKGITVLLHFYALHHN PKVWPNPEVFDPSRFAMNSVQHSHAFLPFSGGSRNCIGKHLAMNVLKVAVALTLLRFELL PDPSRVPIPTQQLVLKSKNGIYLHLRKLQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A087WPC3-F1 Predicted 1-509 pLDDT 91.88
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000083138
MGI Symbol MGI:3717143
NCBI gene (formerly Entrezgene) 230639
UniProtKB Gene Name A0A087WPC3
WikiGene 230639
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 12A
Ensembl ID : ENSMUSG00000066071
Gene Symbol: CYP4A12A
UniProtKB Entry: Q91WL5
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a12a|ENSMUSG00000066071
MSASALSSIRFPGSISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLF GHKILKDQDLQDILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKANGSYRF LAPWIGRGLLMLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVRVMLDKWEQIVGQDST LEIFRHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDII YRVSSNGCKANSACKLAHDHTDQVIKSRRIQLQDEEELEKLKKKRRLDFLDILLFARMEN GKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGTSIT WNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNP TVWPNPEVFDPSRFAPGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP DPTRVPIPIPRIVLKSKNGIHLHLKKLQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q91WL5-F1 Predicted 1-508 pLDDT 92.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000066071
MGI Symbol MGI:88612
NCBI gene (formerly Entrezgene) 277753
UniProtKB Gene Name Q91WL5
WikiGene 277753
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 12B
Ensembl ID : ENSMUSG00000078597
Gene Symbol: CYP4A12B
UniProtKB Entry: A2A974
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a12b|ENSMUSG00000078597
MSASALSSIRFPGSISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLF GHKILKDQDLQDILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKAHGSYRF LAPWIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQDST LEIFQHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNNLFFLRVRNIFHQNDII YRVSSNGCLANSACQLAHDHTDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFARMEN GKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGASIT WNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNP TVWPNPEVFDPSRFAPGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP DPTRVPIPIPRIVLKSKNGIHLHLKKLQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A2A974-F1 Predicted 1-508 pLDDT 92.94
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000078597
MGI Symbol MGI:3611747
NCBI gene (formerly Entrezgene) 13118
UniProtKB Gene Name A2A974
WikiGene 13118
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 30B
Ensembl ID : ENSMUSG00000084346
Gene Symbol: CYP4A30B
UniProtKB Entry: A0A087WS15
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a30b|ENSMUSG00000084346
MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSLQQFPPAPPPQWL FGNTLKDQDLQQILLCVEKFPSTYVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSF FAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCP LEIYQDISLMTMETMMKCAFSYQGSVQLEENSKSYIKAVEDLTHLIYLRVRNGFHQNNTI YSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILLFAQTED GKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTSVT LNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNP RLRPNAEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLP DPTRVPILVSKIVLKSKNGIYLHTKKLK

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A087WS15-F1 Predicted 1-508 pLDDT 90.94
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000084346
MGI Symbol MGI:3717145
NCBI gene (formerly Entrezgene) 435802
UniProtKB Gene Name A0A087WS15
WikiGene 435802
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 14
Ensembl ID : ENSMUSG00000028715
Gene Symbol: CYP4A14
UniProtKB Entry: O35728
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a14|ENSMUSG00000028715
MGFFLFSPTRYLDGISGFFQWAFLLSLFLVLFKAVQFYLRRQWLLKTLQHFPCMPSHWLW GHHLKDKELQQILIWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVLGRSDPKASGIYQFF APWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPL EIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIY NMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDFLDILLFARMEDR NSLSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDGTSVTW DHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPR FWPNPKVFDPSRFAPDSSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPD PTRIPVPIARLVLKSKNGIHLCLKKLR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O35728-F1 Predicted 1-507 pLDDT 92.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000028715
MGI Symbol MGI:1096550
NCBI gene (formerly Entrezgene) 13119
UniProtKB Gene Name O35728
WikiGene 13119
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 10
Ensembl ID : ENSMUSG00000066072
Gene Symbol: CYP4A10
UniProtKB Entry: O88833
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a10|ENSMUSG00000066072
MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFF GHEKFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYR LLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDS SIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDT IYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARME NGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSI TWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHN PKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELL PDPTRVPMPLARLVLKSKNGIYLHLKKLH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O88833-F1 Predicted 1-509 pLDDT 92.81
AlphaFold DB AF-A2A977-F1 Predicted 1-499 pLDDT 92.06
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000066072
MGI Symbol MGI:88611
NCBI gene (formerly Entrezgene) 13117
UniProtKB Gene Name O88833
UniProtKB Gene Name O88833
WikiGene 13117
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 31
Ensembl ID : ENSMUSG00000028712
Gene Symbol: CYP4A31
UniProtKB Entry: A2A8S8
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a31|ENSMUSG00000028712
MSVSALSLTRFAGSLSGFLQVASVFCLLLLLVKAVQVYLHRKWLLKALQQFPSPPFHWFF GHEQFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYR LLAPWIGYGLLLLNGQSWFQHRKMLTPAFHYDILKTYVKNMADSIRLMLDKWERLAGQDS SIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLVHSRVRNMFHQNDT IYKLSSNGRLSNQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARME NEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSI TWDHLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPDGCSLPKGVQVTLSIYGLHHN PKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELL PDPTRVPMSLARFVLKSKNGIYLHLKKVH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-F8WGU9-F1 Predicted 1-509 pLDDT 92.56
AlphaFold DB AF-Q91WU1-F1 Predicted 1-443 pLDDT 84.38
AlphaFold DB AF-A2A8S9-F1 Predicted 1-340 pLDDT 90.06
AlphaFold DB AF-A2A8S8-F1 Predicted 1-155 pLDDT 89.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000028712
MGI Symbol MGI:3028580
NCBI gene (formerly Entrezgene) 666168
UniProtKB Gene Name Q91WU1
UniProtKB Gene Name Q91WU1
UniProtKB Gene Name Q91WU1
UniProtKB Gene Name Q91WU1
WikiGene 666168
CYTOCHROME P450, FAMILY 4, SUBFAMILY A, POLYPEPTIDE 32
Ensembl ID : ENSMUSG00000063929
Gene Symbol: CYP4A32
UniProtKB Entry: A2A8T1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4a32|ENSMUSG00000063929
MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFF GHEQFKGEQELKEVVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSDPKANGIYR LLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDS SIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDT IYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARME NGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSI TWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHN PKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELL PDPTRVPEPLARIVLKSKNGIYLHLKKLH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A2A8T1-F1 Predicted 1-509 pLDDT 92.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000063929
MGI Symbol MGI:3717148
NCBI gene (formerly Entrezgene) 100040843
UniProtKB Gene Name A2A8T1
WikiGene 100040843
CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000028713
Gene Symbol: CYP4B1
UniProtKB Entry: Q3TNA0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4b1|ENSMUSG00000028713
MALSFLSPSLSRLGLWASVVILMVTVLKLLSLLFRRQKLARALDSFPGPPKHWLFGHALE IQKTGGLDKVVTWTEQFPYAHPLWLGQFIVFLNIYEPDYAKAVYSRGDPKAAYVYDFFLQ WIGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDI FCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLT PHGRRFLRACQIAHDHTDHVIRQRKAALQDEKEQKKLQERRHLDFLDILLGARDESGIKL SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRDSFQWDDL AQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWP DPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDP SKIPIKVPQLILRSKNGIHLYLKPLGPGSGK

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3TNA0-F1 Predicted 1-511 pLDDT 93.88
AlphaFold DB AF-Q64462-F1 Predicted 1-511 pLDDT 93.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000028713
MGI Symbol MGI:103225
NCBI gene (formerly Entrezgene) 13120
UniProtKB Gene Name Q64462
UniProtKB Gene Name Q64462
WikiGene 13120
CYTOCHROME P450, FAMILY 11, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000032323
Gene Symbol: CYP11A1
UniProtKB Entry: A0A087WRU6
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp11a1|ENSMUSG00000032323
MLAKGLSLRSVLVKGCQPFLSPTWQGPVLSTGKGAGTSTSSPRSFNEIPSPGDNGWLNLY HFWRESGTQKIHYHQMQSFQKYGPIYREKLGTLESVYIVDPKDASILFSCEGPNPERFLV PPWVAYHQYYQRPIGVLFKSSDAWKKDRIVLNQEVMAPGAIKNFVPLLEGVAQDFIKVLH RRIKQQNSGNFSGVISDDLFRFSFESISSVIFGERMGMLEEIVDPEAQRFINAVYQMFHT SVPMLNLPPDFFRLLRTKTWKDHAAAWDVIFNKADEYTQNFYWDLRQKRDFSQYPGVLYS LLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQAQ GDMAKMVQLVPLLKASIKETLRLHPISVTLQRYTVNDLVLRNYKIPAKTLVQVASFAMGR DPGFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFR IEVQNLRDVGTKFSLILMPENPILFNFQPLKQDLGPAVTRKDNTVN

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A087WRU6-F1 Predicted 1-279 pLDDT 83.88
AlphaFold DB AF-Q9QZ82-F1 Predicted 1-526 pLDDT 89.38
AlphaFold DB AF-A0A087WRA8-F1 Predicted 1-115 pLDDT 55.56
Metabolism R-MMU-1430728
Metabolism of steroid hormones R-MMU-196071
Pregnenolone biosynthesis R-MMU-196108
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000032323
MGI Symbol MGI:88582
NCBI gene (formerly Entrezgene) 13070
UniProtKB Gene Name Q9QZ82
UniProtKB Gene Name Q9QZ82
UniProtKB Gene Name Q9QZ82
WikiGene 13070
CYTOCHROME P450, FAMILY 39, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000023963
Gene Symbol: CYP39A1
UniProtKB Entry: A0A3B2W7Q2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp39a1|ENSMUSG00000023963
MGIMELFSPIAIAVLGSCVLFLFSRLKNLLGPPCIQGWIPWIGAGLEFGKAPLEFIEKAR IKYGPVFTIFAMGNRMTFVSEEEGINVLLKSEHVDFESAVQSPVYHTAWIPKNVFSALHE RLYALMKGKMGTFNTHHFTGPLTEELHEQLEGLGTHGTMDLNDFVRYLLYPATLNTLFKK GLFLTDKRTIKEFYQQFKTYDEGFEYGSQLPEWLLRNWSKSKRWLLALFEKNIGNIKAHG SAGHSGTLLQAILEVVETETRQYSPNYGLVVLWAALANAPPIAFWTLGYILSHPDIHRTV LESISSVFGTAGKDKIKVSEDDLKKLLIIKWCILESVRLRAPGVITRKVVKPVKILNHTV PSGDLLMLSPFWLHRNPKYFPEPESFKPERWKEANLDKYIFLDYFMAFGGGKFQCPGRWF ALLEIQLCIILVLYKYECSLLDPLPKQSSRHLVGVPQPAGKCRIEYKQRA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A3B2W4C8-F1 Predicted 1-404 pLDDT 86.0
AlphaFold DB AF-Q544S6-F1 Predicted 1-470 pLDDT 91.38
AlphaFold DB AF-A0A3B2WCK5-F1 Predicted 1-420 pLDDT 87.19
AlphaFold DB AF-A0A3B2W7Q2-F1 Predicted 1-64 pLDDT 77.5
AlphaFold DB AF-Q9JKJ9-F1 Predicted 1-470 pLDDT 91.62
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-MMU-193775
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000023963
MGI Symbol MGI:1927096
NCBI gene (formerly Entrezgene) 56050
UniProtKB Gene Name Q9JKJ9
UniProtKB Gene Name Q9JKJ9
UniProtKB Gene Name Q9JKJ9
UniProtKB Gene Name Q9JKJ9
UniProtKB Gene Name Q9JKJ9
WikiGene 56050
CYTOCHROME P450, FAMILY 1, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000024087
Gene Symbol: CYP1B1
UniProtKB Entry: Q3UTK2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp1b1|ENSMUSG00000024087
MATSLSADSPQQLSSLSTQQTTLLLLFSVLAAVHLGQWLLRQWQRKPWSSPPGPFPWPLI GNAAAVGQASHLYFARLARRYGDVFQIRLGSCPVVVLNGESAIHQALVQQGSIFADRPPF ASFRVVSGGRSLAFGHYSEHWKTQRRSAYSTMRAFSTRHPRSRGLLEGHALAEARELVAV LVRRCAGGAFLDPTQPVIVAVANVMSAVCFGCRYNHDDAEFLELLSHNEEFGRTVGAGSL VDVLPWLQLFPNPVRTTFRKFEQLNRNFSNFVLDKFLRHRESLVPGAAPRDMTDAFILSA EKKASGAPGDDSSGLDLEDVPATITDIFGASQDTLSTALLWLLILFTRYPDVQARVQAEL DQVVGRDRLPCMSDQPNLPYVMAFLYESMRFSSFLPVTIPHATTANTFVLGYYIPKNTVV FVNQWSVNHDPAKWPNPEDFDPARFLDKDGFINKALASSVMIFSVGKRRCIGEELSKMLL FLFISILAHQCNFKANQNESSNMSFSYGLTIKPKSFRIHVSLRESMELLDNAVKKLQTEE GCK

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64429-F1 Predicted 1-543 pLDDT 91.38
AlphaFold DB AF-Q3UTK2-F1 Predicted 1-487 pLDDT 87.06
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000024087
MGI Symbol MGI:88590
NCBI gene (formerly Entrezgene) 13078
UniProtKB Gene Name Q64429
UniProtKB Gene Name Q64429
WikiGene 13078
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 13
Ensembl ID : ENSMUSG00000028571
Gene Symbol: CYP2J13
UniProtKB Entry: Q3UNV4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j13|ENSMUSG00000028571
MLEAADSLAAAFWAALHLRTLLLAAVTFLFLADYLKSRRPKNYPPRPPRLPFVGNSFQMD LTQSHLAVQKFVKKYGNVISLDFGIKSAVIISSLPLIKEAFSHLDENFINRRIFPLQRQI FNGNGLIFSSGQTWKEQRRFALMTLRNFGLGKKSLEHRIQEEASHLVEAIGEEEGQPFDP HFKIYSAVSNIICSITFGERFEYHDSQFQELLQLLDKAMYLGTTSLMVHLYNIFPWITKH LPGQHQTLLATWRKLKSYIADIIDNHRKDWNPDEPRDFIDAFLNEMAKYPGKTTTSFNEE NLICSTLDLFLAGTETTSSTLRWALLYMALYPEVQENVQAEIDRVIGQSKHPSLADRDSM PYTNAVVHEILRMGNSVPLNIPREVAVDTTLAGFHLPKRSVVMTNLTALHMDPKEWATPD IFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTALVQKFTFKPPANENL SLKFRLGITISPVSYRIGAVPRQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B1AWM4-F1 Predicted 1-374 pLDDT 79.06
AlphaFold DB AF-Q3UNV4-F1 Predicted 1-503 pLDDT 92.56
AlphaFold DB AF-B1AWM5-F1 Predicted 1-433 pLDDT 86.94
Expression Atlas ENSMUSG00000028571
MGI Symbol MGI:2385197
NCBI gene (formerly Entrezgene) 230459
UniProtKB Gene Name Q3UNV4
UniProtKB Gene Name Q3UNV4
UniProtKB Gene Name Q3UNV4
WikiGene 230459
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 12
Ensembl ID : ENSMUSG00000081225
Gene Symbol: CYP2J12
UniProtKB Entry: G3UXT0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j12|ENSMUSG00000081225
MLATEDTFETAIWALLHFKTLVLAAVTFMLLAHYLKTQRPKNYPPGPWRLPFVGNLFQLD LEQPHVVIQQFVKKYGNLTSLDFGNIPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRV FNNNGLIISNGQTWKEQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDP HFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYV PGSHQTVLRNWEKLKLFIYQMMESHRKDWNPDEPRDFIDAFLTEMSKYGDKTTTSFNEEN LINSTLDLFFAGSETTTNTLRWALLYITTNPEVQEKVHSEIDRVIGHGRQPSTDDRDSMP YTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNT FNPEHFLENGQFKKRESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFKPPINEKLS LKFRNGLTLSPVSHCICAVPRH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-G3UZ89-F1 Predicted 1-71 pLDDT 70.62
AlphaFold DB AF-G3UXT0-F1 Predicted 1-502 pLDDT 92.94
Expression Atlas ENSMUSG00000081225
MGI Symbol MGI:3717097
NCBI gene (formerly Entrezgene) 242546
UniProtKB Gene Name G3UZ89
UniProtKB Gene Name G3UZ89
WikiGene 242546
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 7
Ensembl ID : ENSMUSG00000081362
Gene Symbol: CYP2J7
UniProtKB Entry: A0A140T8U1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j7|ENSMUSG00000081362
MLSTVGSLVARIWSAIHLWTLLLTLLVFRLLADYLKNRRPKNYPPGPWRLPFVGNLFQFD LDVSQLHLRIQLFVKKYGNLISIDFGNISSVVITGLPLIKEAFTDMEQNLLKRPIIPSRK HVFKDNGIIFSSGQKWKEQRRFALMILKSFGLGKKSLEQRIQEEAYHLVKAMEEEKGQPF DPHFRINSAVSNIICSINFGERFEYGDNKFQELLKITNETLSAETSMMLVLYNALPSIMK YLPGPHQTVFRNWERLKMIVYHMMESHRKDWNPDEPRDFIDAFLTEMTKYPDKTTTSFNE ENLICSCLDLFIAGTETSSTALRWALLYMTLNPEVQERVHSEIDGVIGQWRQPSTGDRDS MPYTNAVIHEVLRMGNIVPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATP DIFNPEHFLENGQFKKRESFLPFSMGKRACPGEQLARTELFIFFTALMQKFTFKAPVNEK LSLKFRMSVPISPVSYCICAVPRQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A140T8U1-F1 Predicted 1-504 pLDDT 92.81
Expression Atlas ENSMUSG00000081362
MGI Symbol MGI:2449816
NCBI gene (formerly Entrezgene) 546837
UniProtKB Gene Name A0A140T8U1
WikiGene 546837
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 11
Ensembl ID : ENSMUSG00000066097
Gene Symbol: CYP2J11
UniProtKB Entry: Q3UNV2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j11|ENSMUSG00000066097
MLAIATCLVANICSAIHLWTLLLTLLTLLLLADYLKNRRPKNYPPGPRRLPFVGNLFQFD LDVSRLHLGIQPFVKKYGNVISVNFGYISSVIISGLPLIKEAITGMEQNFLKRPSLAARQ HVFKNNGIVFSSGQTWKEQRKFALTILKNFGLGKKSLEQCIQEEAYHLVKAIGEEKGQPF DPHFRINNAVGNIICSIIFGERFEYDDNQFQELLKLADEIICSEASMMSVLYNVFPSIFK YLPGPQQKLFSNWEKLKLFVSRMMDSHREDWNPSAPRDFIDAFLTEMTKYPDKTTTSFNE ENLICTALDLFFAGTETTSNTLRWALLYITVNPEVQEKVHSEIDRVIGHGRHPTLDDQDS MPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAGFYLPKGTMVLINLTDLHRDPKEWDTP NVFNPEHFLENGQFKKKESFLPFSMGKRACPGEQLASCELFIFFTALMQKFTFKSPINEK PSLKFRMGLTLAPVSYRICAVPRL

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3UNV2-F1 Predicted 1-504 pLDDT 92.19
Expression Atlas ENSMUSG00000066097
MGI Symbol MGI:2140224
NCBI gene (formerly Entrezgene) 100066
UniProtKB Gene Name Q3UNV2
WikiGene 100066
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 8
Ensembl ID : ENSMUSG00000082932
Gene Symbol: CYP2J8
UniProtKB Entry: G3UZ38
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j8|ENSMUSG00000082932
MFATIGCLVSNICSEIHLWTLLLAALTLLLLVDYIKNRHPKNYPPGPWRLPFVGNLFQFD LDVSHLHLGIQPFVKKYGNLISLDFGTIPSVIISGEPLIKEALTCMGQNFLKRPILAARQ HIFKNNGIISSSGQTWKEQRRFTLMILKNFGLGKKSLEQRIQDEAHHLVEAIAEEKGRPF DPHFMINNAVSNIICSITIGERFEYEDNQFQELLKLADETLCLEASKVLMLYNVFPSIFK YLPGPHQKLFSNWEKLKLFFSHVMDSHRKDWNPSAPRDFIDAFLTEMAKYSDKTTTSFNE ENLICTTLDLFFAGTETTSTALRWALLYITVNPEVQEKVHSEIDRVIGQGRHPTIDDRDS MPYTNAVIHEVLRMGNIIPLNVPREVEADITLAGFHLPKGTMVLTNLTALHRDPKEWATP DVFNPEHFLENGQFKKRESFLPFSVGKRGCPGEQLARSELFTFFTALMQKFTFKPPINEK LSLNFKMGVALSPVSYCICAVPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-G3UZ38-F1 Predicted 1-503 pLDDT 93.12
Expression Atlas ENSMUSG00000082932
MGI Symbol MGI:2449817
NCBI gene (formerly Entrezgene) 665095
UniProtKB Gene Name G3UZ38
WikiGene 665095
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 6
Ensembl ID : ENSMUSG00000052914
Gene Symbol: CYP2J6
UniProtKB Entry: O54750
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j6|ENSMUSG00000052914
MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLD FGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERI SNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNP HFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYI PGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENL ICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPY TNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVF NPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSP KFRNGLTLSPVSHRICAVPRQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O54750-F1 Predicted 1-501 pLDDT 92.5
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000052914
MGI Symbol MGI:1270148
NCBI gene (formerly Entrezgene) 13110
UniProtKB Gene Name O54750
WikiGene 13110
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 9
Ensembl ID : ENSMUSG00000015224
Gene Symbol: CYP2J9
UniProtKB Entry: Q924D1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j9|ENSMUSG00000015224
MLAAAGSLVAAIWAALHLRILLLSAVTFLFLADFLKNRRPKNYPPGPMRLPFVGCLFHLD PKQPHLSLQQFVKKYGNVLSLDFANIPSVVITGMPLIKEIFTQMEHNFMNRPVTLLRKHL FNKNGLIFSSDQTWKEQRRFALMTLRNFGLGKRSLEERIQEEAHYLVEAIRDEGGQPFDP HFNISNAVSNIICSITFGERFDYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYL PGSHQTLFRNWRKLQLFVSDIVNNHRRDWDPDEPRDFIDAFLTEMTKYPDKTTTSFNEEN LICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQARQPNLADRDSMP YTNAVIHEVQRMGNIIPFNVPREVAVDTQLAGFNLPKGIMVLSNLTALHRDPSEWTTPDT FNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFITTLFQKFTFKPPVNEKLS LQFRMAATVSPVSHRLCAIPRL

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q924D1-F1 Predicted 1-502 pLDDT 92.44
Expression Atlas ENSMUSG00000015224
MGI Symbol MGI:1921769
NCBI gene (formerly Entrezgene) 74519
UniProtKB Gene Name Q924D1
WikiGene 74519
CYTOCHROME P450, FAMILY 2, SUBFAMILY J, POLYPEPTIDE 5
Ensembl ID : ENSMUSG00000052520
Gene Symbol: CYP2J5
UniProtKB Entry: Q3TNC5
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2j5|ENSMUSG00000052520
MIMFLSSLVTTFWEALHLKTLVLAVVTFLFLINILRSRHPKNYPPGPWRLPFVGNFFQID TKQTHLVLQQFVKKYGNVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERI TGKNGLVVSNGQTWKEQRRLALMALRNFGLGKKSLEERIQEETHHLVEAIREEGGQPFNP HLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYL PGPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEPRDFIDAFLIEMQKDPDRTTSFNEENL ISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDRESMPY TNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVF NPEHFLENGQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKPPINEKLSL KFRMGLILSPASYRICAIPRV

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O54749-F1 Predicted 1-501 pLDDT 93.12
AlphaFold DB AF-Q3TNC5-F1 Predicted 1-501 pLDDT 92.44
Expression Atlas ENSMUSG00000052520
MGI Symbol MGI:1270149
NCBI gene (formerly Entrezgene) 13109
UniProtKB Gene Name Q3TNC5
UniProtKB Gene Name Q3TNC5
WikiGene 13109
CYTOCHROME P450, FAMILY 7, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000039519
Gene Symbol: CYP7B1
UniProtKB Entry: Q60991
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp7b1|ENSMUSG00000039519
MQGATTLDAASPGPLALLGLLFAATLLLSALFLLTRRTRRPREPPLIKGWLPYLGMALKF FKDPLTFLKTLQRQHGDTFTVFLVGKYITFVLNPFQYQYVTKNPKQLSFQKFSSRLSAKA FSVKKLLTDDDLNEDVHRAYLLLQGKPLDALLETMIQEVKELFESQLLKITDWNTERIFA FCGSLVFEITFATLYGKILAGNKKQIISELRDDFFKFDDMFPYLVSDIPIQLLRNEESMQ KKIIKCLTSEKVAQMQGQSKIVQERQDLLKRYYRHDDPEIGAHHLGFLWASLANTIPAMF WAMYYILRHPEAMEALRDEIDSFLQSTGQKKGPGISVHFTREQLDSLVCLESTILEVLRL CSYSSIIREVQEDMNLSLESKSFSLRKGDFVALFPPLIHNDPEIFDAPKEFRFDRFIEDG KKKSTFFKGGKKLKTYVMPFGLGTSKCPGRYFAVNEMKLLLIMLLTYFDLEIIDRKPIGL NHSRMFLGIQHPDSAVSFRYKAKSWRS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q60991-F1 Predicted 1-507 pLDDT 91.69
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000039519
MGI Symbol MGI:104978
NCBI gene (formerly Entrezgene) 13123
UniProtKB Gene Name Q60991
WikiGene 13123
CYTOCHROME P450, FAMILY 26, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000063415
Gene Symbol: CYP26B1
UniProtKB Entry: A0A0N4SUV4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp26b1|ENSMUSG00000063415
MLFEGLELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIG ETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRS ARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSQPEAIN VYQEAQRLTFRMAVRVLLGFSIPEEDLGHLFEVYQQFVENVFSLPVDLPFSGYRRGIQAR QILQKGLEKAIREKLQCTQGKDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYAT TASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKE VMRLFTPVSGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQA RSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVL HPVDGLSVKFFGLDSNQNEILPETEAMLSATV

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0N4SV88-F1 Predicted 1-437 pLDDT 82.31
AlphaFold DB AF-Q811W2-F1 Predicted 1-512 pLDDT 90.62
AlphaFold DB AF-A0A0N4SUV4-F1 Predicted 1-321 pLDDT 87.44
Metabolism R-MMU-1430728
Signal Transduction R-MMU-162582
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Signaling by Retinoic Acid R-MMU-5362517
RA biosynthesis pathway R-MMU-5365859
Signaling by Nuclear Receptors R-MMU-9006931
Expression Atlas ENSMUSG00000063415
MGI Symbol MGI:2176159
NCBI gene (formerly Entrezgene) 232174
UniProtKB Gene Name Q811W2
UniProtKB Gene Name Q811W2
UniProtKB Gene Name Q811W2
WikiGene 232174
CYTOCHROME P450, FAMILY 2, SUBFAMILY R, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000030670
Gene Symbol: CYP2R1
UniProtKB Entry: F6RCB2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2r1|ENSMUSG00000030670
MLELPGARACAGALAGALLLLLFVLVVRQLLRQRRPAGFPPGPPRLPFVGNICSLALSAD LPHVYMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTK MGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGGPFDLK QLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPF GKHQRLFRNADVVYDFLSRLIEKAAVNRKPHLPHHFVDAYLDEMDQGQNDPLSTFSKENL IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCKMPY TEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMF YPERFLDSNGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFPHELVPN LKPRLGMTLQPQPYLICAERR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-D6RCU9-F1 Predicted 1-83 pLDDT 60.06
AlphaFold DB AF-F6RCB2-F1 Predicted 1-268 pLDDT 95.19
AlphaFold DB AF-D3YTX0-F1 Predicted 1-290 pLDDT 78.38
AlphaFold DB AF-Q32MW1-F1 Predicted 1-501 pLDDT 95.44
AlphaFold DB AF-A0A1B0GRJ1-F1 Predicted 1-292 pLDDT 96.19
AlphaFold DB AF-Q6VVW9-F1 Predicted 1-501 pLDDT 95.69
Metabolism R-MMU-1430728
Vitamin D (calciferol) metabolism R-MMU-196791
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000030670
MGI Symbol MGI:2449771
NCBI gene (formerly Entrezgene) 244209
UniProtKB Gene Name Q6VVW9
UniProtKB Gene Name Q6VVW9
UniProtKB Gene Name Q6VVW9
UniProtKB Gene Name Q6VVW9
UniProtKB Gene Name Q6VVW9
UniProtKB Gene Name Q6VVW9
WikiGene 244209
CYTOCHROME P450, FAMILY 2, SUBFAMILY AB, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000022818
Gene Symbol: CYP2AB1
UniProtKB Entry: E9PZ31
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2ab1|ENSMUSG00000022818
MFSLFSGMAFLAGSCLLLKLATLCWRRSHLPPGPFPFPLLGNLWQLNFQLHPNMLFQLAQ THGSVFTVWLGSTPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLT WRQQRRFCLTTLRELGLGKQALEVQLQHEAAELAKVFLQEEGRAFDPQIPIIRSTTRVIG TLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALRHLSGPHQKIFQYHEA VRGFIRHEIIRHKLRTAEAPKDFINCYLSQITKAIDDPVSTFSEENLIQVVIDLFLGGTD TTATTLHWALIYLVHHRAIQERVQQELDEMLGAAQTICYEDRERLPYTRAVLHEVQRLSS VVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFV ANEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFQFQLPEGSQDLGLEYVFGGTLQPQ PQKICAVLRQSSLSPREP

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-S4R196-F1 Predicted 1-498 pLDDT 89.75
AlphaFold DB AF-E9PZ31-F1 Predicted 1-280 pLDDT 92.31
Expression Atlas ENSMUSG00000022818
MGI Symbol MGI:3644957
NCBI gene (formerly Entrezgene) 224044
UniProtKB Gene Name S4R196
UniProtKB Gene Name S4R196
WikiGene 224044
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 39
Ensembl ID : ENSMUSG00000061126
Gene Symbol: CYP4F39
UniProtKB Entry: Q8BGU0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f39|ENSMUSG00000061126
MLPLTDYLLQLLGLEKTAFRVYVVSALLLLVLFFFFRLLVRAFKLFSDFRITCRKLSCFP EPPGRHWLLGHMSMYLPNEKGLQNEKKVLDTMHHIILAWVGPFLPLLVLVHPDYIKPVLG ASAAIAPKDEFFYSFLKPWLGDGLLISKGNKWSRHRRLLTPAFHFDILKPYMKIFNQCTN IMHAKWRRHLAEGSVTSFDMFEHISLMTLDSLQKCVFSYNSDCQERMSDYISSIIELSAL VVRRQYRLHHYLDFMYYLTADGRRFRQACDTVHNFTTEVIQERRQALRQQGAEAWLKAKQ GKTLDFIDVLLLAKDEEGKELSDEDIRAEADTFMFEGHDTTSSGLSWALFNLAKYPEYQE KCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKESLRQFPPVTLISRRCTEDIKLPDGR VIPKGIICLVSIYGTHHNPIVWPDSKVYNPYRFDPDTPQQRSPLAFVPFSAGPRNCIGQS FAMAEMRVVVALTLLRFRLSVDRTHKVRRKPELILRTENGLWLNVEPLPSRA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A494BAE0-F1 Predicted 1-105 pLDDT 83.44
AlphaFold DB AF-Q8BGU0-F1 Predicted 1-532 pLDDT 93.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000061126
MGI Symbol MGI:2445210
NCBI gene (formerly Entrezgene) 320997
UniProtKB Gene Name Q8BGU0
UniProtKB Gene Name Q8BGU0
WikiGene 320997
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 17
Ensembl ID : ENSMUSG00000091586
Gene Symbol: CYP4F17
UniProtKB Entry: G3UW78
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f17|ENSMUSG00000091586
MLQLGLSWLGLGPGAAFPWQLLQLVGASLFLARILTWICAFYDNYCRLRCFPEPPSRHWF WGHMSMVKNNEEGLQLLTERSHQFHDVHLCWIGPFYPILRLIHPKFIGPILQASAAVAPK EMIFYGFLKPWLGDGLLVSAGEKWSRHRHLLTPAFHFDILKPYMKNFNKSVNIMHAKWQR LTTKGTACLDMLEHISLMTLDSLQNCVFSFDSNCQESPSEYIAAIQELSSLIVKRHHQPF LYLDFLYYCTADGRRFRKACDLVHNFTDAVIRERRRTLSSQNLDEFLKSKTKSKTLDFID VLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQE LLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDVVLPDGRVIPKGTDC VISIFGVHHNPEVWPDPEVYDPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMREMKV ALALTLLRFRVLPGDKEPRRKPELILRAEGGLWLRVEPLSKGTQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A494BA08-F1 Predicted 1-177 pLDDT 88.38
AlphaFold DB AF-G3UW78-F1 Predicted 1-524 pLDDT 91.25
Expression Atlas ENSMUSG00000091586
MGI Symbol MGI:3646233
NCBI gene (formerly Entrezgene) 208285
UniProtKB Gene Name G3UW78
UniProtKB Gene Name G3UW78
WikiGene 208285
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 16
Ensembl ID : ENSMUSG00000048440
Gene Symbol: CYP4F16
UniProtKB Entry: Q99N17
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f16|ENSMUSG00000048440
MLRLSVSGLDLGSVVTSSWHLLLLGVASWILARILAWTYSFYENCSRLSCFPQPPKKNWF SGHLGMIQSNEEGMQLVTEMGQTFQDVHLFWLGPVIPVLRIVDPAFVAPLLQAPALVAPK DMTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKH LSSEGSARLEMFEHISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSSLIIKRSLQLF LFVDFLYYHTADGRRFRKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKTKSKTLDFID VLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQE LLRDREPEEIEWDDLAQLPFLTMCIKESLRLHSPVIDLLRRCTRDIVLPDGRVIPKGNIC VISIFGIHHNPSVWPDPEVYDPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEMKV ALALTLLRFRILPDDKEPRRKPEIILRAEGGLWLRVEPLSKGAQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9PW68-F1 Predicted 1-73 pLDDT 73.25
AlphaFold DB AF-E9QB04-F1 Predicted 1-71 pLDDT 72.94
AlphaFold DB AF-Q99N17-F1 Predicted 1-524 pLDDT 91.5
Expression Atlas ENSMUSG00000048440
MGI Symbol MGI:1917351
NCBI gene (formerly Entrezgene) 70101
UniProtKB Gene Name Q99N17
UniProtKB Gene Name Q99N17
UniProtKB Gene Name Q99N17
WikiGene 70101
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 37
Ensembl ID : ENSMUSG00000062464
Gene Symbol: CYP4F37
UniProtKB Entry: Q3V1F1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f37|ENSMUSG00000062464
MLRLSVSGLDLGSVVTLSWHLLLLGAASWILARILAWTYSFCENCSRLRCFPQPPKRNWF LGHLGMIEHNEEGMQLMTEAGQTYRDVHLCWLGPVIPVLRIVDPAFVAPLLLASALVAPK DTTFHTFVKPWLGDGLFLNSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKH LSSEGSARLEMFEHISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSSLVIKRSHQLF LFVDFLYYHTADGRRFRKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKTKSKTLDFID VLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQE LLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVIDLLRRCTRDIVLPDGRVIPKGNIC VISIFGIHHNPSVWPDPEVYDPFRFDPENAHKRPPLAFIPFSAGPRNCIGQTFAMNEMMV ALALTLLRFRILPDDKEPRRKPEIILRAEGGLWLRVEPLSTVLKDSKPDLEASLPHPPIV LSGSQN

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3V1F1-F1 Predicted 1-546 pLDDT 88.88
Expression Atlas ENSMUSG00000062464
MGI Symbol MGI:3780112
NCBI gene (formerly Entrezgene) 677156
UniProtKB Gene Name Q3V1F1
WikiGene 677156
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 40
Ensembl ID : ENSMUSG00000090700
Gene Symbol: CYP4F40
UniProtKB Entry: G3UW81
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f40|ENSMUSG00000090700
MRYLDLSWLGLGPMSASPWLLFFLVGISWFLARFLTQLYTLYAKCQRLCGFPQPPKKNWF WGHLGMSPPTEEGMKQVTELVTTYPQGFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPK DDIFYSFLKPWLGDGLLVSAGDKWNRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWLR LASGGSTRLNMFENISLMTLDTLQKCVFSFNSNCQEKPSQYIAAILELSTLAVKRNEQLL MHVDLLYRLTPDGMRFYKACRLVHDFTDAVIQERRRTLLKHGGDDIIKAKAKSKTLDFID VLLLTKDEDGKELSDEDIRAEADTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQE LLRDRDPKEIEWDDLAQLPFLTMCIKESLRLHPPVTMVSRCCTQDISLPDGRIIPKGVIC IINIFGTHHNPTVWRDPEVYDPFRFDPENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKV ALALTLLRFRILPDDKEPRRKPELILRAEGGLWLRVEPLSTQAQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-G3UW81-F1 Predicted 1-524 pLDDT 91.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000090700
MGI Symbol MGI:3645508
NCBI gene (formerly Entrezgene) 631304
UniProtKB Gene Name G3UW81
WikiGene 631304
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 15
Ensembl ID : ENSMUSG00000073424
Gene Symbol: CYP4F15
UniProtKB Entry: Q99N18
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f15|ENSMUSG00000073424
MGFFRMPQLDLSWLGLRLEASSPWLLLLLIGASWLLARVLTQTYIFYRTYHHLCDFPQPP KWNWFLGHLGMITPTEHGLKEVTNLVATYPQGFMTWLGPIIPIITLCHPDIIRSVLNASA SVALKEVVFYSFLKPWLGDGLLLSDGDKWSSHRRMLTPAFHFNILKPYVKIFNDSTNIMH AKWQHLASGGSARLDVFENISLMTLDSLQKCVFSFDSNCQENPSEYISAILELSALVTKR YHQLLLHIDSLYQLTCSGRRFHKACHLVHSFTDAVIQDRRRTLPSKHEDDVLKAKAKSKT LDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCR QEVQELLRDRESTEIECSCAVFLRDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVL PDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNC IGQTFAMNEMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLRVEPLSTQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q8VCA4-F1 Predicted 1-527 pLDDT 90.75
AlphaFold DB AF-Q99N18-F1 Predicted 1-534 pLDDT 88.0
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000073424
MGI Symbol MGI:2146921
NCBI gene (formerly Entrezgene) 106648
UniProtKB Gene Name Q99N18
UniProtKB Gene Name Q99N18
WikiGene 106648
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 14
Ensembl ID : ENSMUSG00000024292
Gene Symbol: CYP4F14
UniProtKB Entry: A0A3Q4EC89
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f14|ENSMUSG00000024292
MSQLSLSWLGLGPEVAFPWKTLLLLGASWILARILIQIYAAYRNYRHLHGFPQPPKRNWL MGHVGMVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALK DVIFYSILKPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQR LISDGSARLDMFEHVSLMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPL MFMDLLYNLTPDGMRFRKACNVVHEFTDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFID VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQE LLRGREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIIC LISIFGIHHNPSVWPDPEVYDPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKV ALALTLLRFRLLPDDKEPRRQPELILRAEGGLWLRVEPLSAGAH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9EP75-F1 Predicted 1-524 pLDDT 91.44
AlphaFold DB AF-A0A3Q4EC89-F1 Predicted 1-159 pLDDT 86.38
AlphaFold DB AF-A0A3Q4EHX3-F1 Predicted 1-243 pLDDT 87.31
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000024292
MGI Symbol MGI:1927669
NCBI gene (formerly Entrezgene) 64385
UniProtKB Gene Name Q9EP75
UniProtKB Gene Name Q9EP75
UniProtKB Gene Name Q9EP75
WikiGene 64385
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 13
Ensembl ID : ENSMUSG00000024055
Gene Symbol: CYP4F13
UniProtKB Entry: A0A3Q4EGQ8
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f13|ENSMUSG00000024055
MLQLCLSWLGMGSLTASPWHLLLLGGASWILARILAWIYAFYDNCSRLRCFPQPPKPSWF WGHLALMKNNEESMQFITHLGHDFHDVHLSWVGPVYPILRLVHPNFIAPLLQASAAVAPK EMTLYGFLKPWLGDGLLMSAGDKWSHHRRLLTPAFHFDILKSYVKIFNKSVNIMHAKWQC LASKGTSRLDMFEHISLMTLDSLQKCIFSVDSNCQESDSKYIAAILELSSLVVKRHRQPF LYLDLLYYLTADGRRFRKACDLVHNFTDAVIKERRSTLNTQGVEFLKAKAKTKTLDFIDV LLMAEDEHGKGLSNEDIRAEADTFMFGGHDTTTSALSWILYNLARHPEYQERCRQEVQEL LRDRDSEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCTQDVLLPDGRAIPKGNICV ISIFGVHHNPSVWPDPEVYNPFRFDPENPQKRSPLAFIPFSAGTRNCIGQTFAMSEIKVA LALTLLRFRILPDDKEPRRKPELILRAEGGLWLRVEPLSAGAQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B8JK07-F1 Predicted 1-414 pLDDT 83.69
AlphaFold DB AF-A0A3Q4EBU2-F1 Predicted 1-216 pLDDT 89.5
AlphaFold DB AF-Q99N19-F1 Predicted 1-523 pLDDT 92.0
AlphaFold DB AF-E9Q4L9-F1 Predicted 1-115 pLDDT 80.75
AlphaFold DB AF-D6RH52-F1 Predicted 1-87 pLDDT 70.38
AlphaFold DB AF-G3UVU3-F1 Predicted 1-118 pLDDT 78.25
AlphaFold DB AF-A0A3Q4EGQ8-F1 Predicted 1-73 pLDDT 74.12
Expression Atlas ENSMUSG00000024055
MGI Symbol MGI:2158641
NCBI gene (formerly Entrezgene) 170716
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
UniProtKB Gene Name Q99N19
WikiGene 170716
CYTOCHROME P450, FAMILY 46, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000021259
Gene Symbol: CYP46A1
UniProtKB Entry: Q3US73
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp46a1|ENSMUSG00000021259
MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVL QDVFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERL FGQGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSM QDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPGKRKQL REIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDNFVTFF IAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKES LRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA PKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKPLD PVLCTLRPRGWQPAPPPPPC

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9WVK8-F1 Predicted 1-500 pLDDT 94.06
AlphaFold DB AF-A0A1Y7VM34-F1 Predicted 1-112 pLDDT 88.75
AlphaFold DB AF-Q3US73-F1 Predicted 1-500 pLDDT 93.31
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-MMU-193775
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000021259
MGI Symbol MGI:1341877
NCBI gene (formerly Entrezgene) 13116
UniProtKB Gene Name Q9WVK8
UniProtKB Gene Name Q9WVK8
UniProtKB Gene Name Q9WVK8
WikiGene 13116
CYTOCHROME P450, FAMILY 20, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000049439
Gene Symbol: CYP20A1
UniProtKB Entry: Q8BKE6
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp20a1|ENSMUSG00000049439
MLDFAIFAVTFLLALVGAVLYLYPASRQASGIPGLTPTEEKDGNLPDIVNSGSLHEFLVN LHERYGPVVSFWFGRRLVVSLGTTDVLKQHFNPNKTSDPFETMLKSLLGYQSGGGSAGED HVRRKLYGDAVTASLHSNFPLLLQLSEELLDKWLSYPETQHIPLSQHMLGFALKFVTRMV LGSTFEDEQEVIRFQKIHGTVWSEIGKGFLDGSLDKNTTRKKQYQEALMQLESTLKKIIK ERKGGNFRQHTFIDSLTQGKLNEQQILEDCVVFSLASCIITARLCTWTIHFLTTTGEVQK KLCKEIDQVLGEGPITSEKIEQLSYCQQVLFETVRTAKLTPVSARLQDIEGKVGPFVIPK ETLVLYALGVVLQDPSTWPLPHRFDPDRFADEPVMKVFSSLGFSGTWECPELRFAYMVTA VLVSVLLKRLRLLAVDRQVFEMKYELVTSAREEAWITVSKRH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-J3QPT8-F1 Predicted 1-44 pLDDT 78.5
AlphaFold DB AF-Q8BKE6-F1 Predicted 1-462 pLDDT 88.38
Expression Atlas ENSMUSG00000049439
MGI Symbol MGI:1925201
NCBI gene (formerly Entrezgene) 77951
UniProtKB Gene Name Q8BKE6
UniProtKB Gene Name Q8BKE6
WikiGene 77951
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 12
Ensembl ID : ENSMUSG00000096852
Gene Symbol: CYP2D12
UniProtKB Entry: B7ZP10
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d12|ENSMUSG00000096852
MELLTGTDLWSVAIFTVIFILLVDLMHRRQSWTSCYPPGPVPWPVLGNLLQVDLNNMPYS LYKLQNRYGDVFSLQMAWKPMVVINRMKAMKEVLLTCGEDTADRPPVPIFEHLGFKPRSQ GMIFAPYGPEWREQRRFSLSSLRNFGLGRKSLEEWVIKEAGHLCDAFTTQAGQYINPNTM LKKATCNVIASLIFARRFEYEDPYLIRMLKVLEDSLTELSGLIPEVINTFPILLHIPRLA DKFLQSQKSFIAIVDNLLTENRTTWDPAQSPRNLTDAFLAEIEKAKGNPESSFNDENLRM VVIDLFTAGILTTSTTLSWALLLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTN AVIHEVQRFGDIVPLHLPRITSRDIEVQDFLIPKGTILLPNMSSVHMDDTVWEKPLRFHP EHFLDAQGHFVKHEAFITFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPQPSD HRVFSIMVAPSPYQLCAVIREQGH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q8BVD2-F1 Predicted 1-504 pLDDT 92.81
AlphaFold DB AF-A0A2R8VJY6-F1 Predicted 1-158 pLDDT 78.5
AlphaFold DB AF-B7ZP10-F1 Predicted 1-453 pLDDT 80.5
AlphaFold DB AF-A0A2R8VHA2-F1 Predicted 1-92 pLDDT 60.69
Expression Atlas ENSMUSG00000096852
MGI Symbol MGI:88604
NCBI gene (formerly Entrezgene) 380997
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
WikiGene 380997
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 34
Ensembl ID : ENSMUSG00000094559
Gene Symbol: CYP2D34
UniProtKB Entry: L7N463
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d34|ENSMUSG00000094559
MELLTGTGLWSVAIFTVIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNIPYS LYKLQNRYGDVFSLQMAWKPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQ GVVLASYGPEWREQRQFSVSTLRNFGLGKKSLEEWVTKEAKHLCDAFTARAGQSINPNTM LNNAVCNVIASLIFARRFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFPILLRIPGLA DMVFQSQKTFMAILDNLVTENRTTWDPDQPPRNLADAFLAEIQKAKGNPESSFNDENLCM VVSDLFTAGMVTTSTTLSCALLLMILHPDVQRRVQQEIDAVIGQVRCPEMADQARMPYTN AVIHEVQRFGDIIPLNIPRITSRDIEVQDFLIPKGTILIPNMSSMLKDETVWEKPLRFYP EHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPAGQPQPSD HRIFAIPVAPYPYQVCAIMREQGH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VHH8-F1 Predicted 1-92 pLDDT 63.28
AlphaFold DB AF-L7N463-F1 Predicted 1-504 pLDDT 91.38
Expression Atlas ENSMUSG00000094559
MGI Symbol MGI:2385022
NCBI gene (formerly Entrezgene) 223706
UniProtKB Gene Name L7N463
UniProtKB Gene Name L7N463
WikiGene 223706
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 40
Ensembl ID : ENSMUSG00000068083
Gene Symbol: CYP2D40
UniProtKB Entry: Q6P8N9
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d40|ENSMUSG00000068083
MELLTGTDLWPVAIFTVIFILLVDLLHRRQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYS FYKVVKMFPIVLRIPGLADKIFPGQKTFLTMVDKLVTEHKRTWDPDQPPRDLTDAFMAEM ETAKGNPESSFNEANLRLVVLDLFGGGIVTTSATLTWALLLMILHPDVQRRVQEEIDEVI GQARRPEMADQARMPYTNAVIHEVQRFADIAPMTLPHRTSCDIEVQGFLIPKGTTLICNL SSVLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMPFSAGRRACLGEPLVRMELFLFFTC LLQRFSFSVPDGQPLPSDYGIYSMVVSPAPYQLCAVVR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q6P8N9-F1 Predicted 1-338 pLDDT 88.38
Expression Atlas ENSMUSG00000068083
MGI Symbol MGI:1919004
NCBI gene (formerly Entrezgene) 71754
UniProtKB Gene Name Q6P8N9
WikiGene 71754
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 26
Ensembl ID : ENSMUSG00000022445
Gene Symbol: CYP2D26
UniProtKB Entry: A0A2R8W716
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d26|ENSMUSG00000022445
MGLLVGDDLWAVVIFTAIFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYS FYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSK GVILAPYGPEWREQRRFSVSTLRDFGLGKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPL LSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLP DKAFPKLNSFIALVNKMLIEHDSTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRI VVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMADQARMPYTN AVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYP EHFLDAQGHFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSD YGIYTMPVTPEPYQLCAVAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VI97-F1 Predicted 1-95 pLDDT 79.19
AlphaFold DB AF-A0A2R8W716-F1 Predicted 1-92 pLDDT 60.62
AlphaFold DB AF-A0A0R4IZY2-F1 Predicted 1-500 pLDDT 91.62
Expression Atlas ENSMUSG00000022445
MGI Symbol MGI:1923529
NCBI gene (formerly Entrezgene) 76279
UniProtKB Gene Name A0A2R8W716
UniProtKB Gene Name A0A2R8W716
UniProtKB Gene Name A0A2R8W716
WikiGene 76279
CYTOCHROME P450, FAMILY 7, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000028240
Gene Symbol: CYP7A1
UniProtKB Entry: Q64505
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp7a1|ENSMUSG00000028240
MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQ RKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGN TTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMF EAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAE SLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQ MIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSAS LNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAK TTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLD QSRAGLGILPPLNDIEFKYKLKH

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64505-F1 Predicted 1-503 pLDDT 93.62
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000028240
MGI Symbol MGI:106091
NCBI gene (formerly Entrezgene) 13122
UniProtKB Gene Name Q64505
WikiGene 13122
CYTOCHROME P450, FAMILY 11, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000075604
Gene Symbol: CYP11B1
UniProtKB Entry: Q3TG86
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp11b1|ENSMUSG00000075604
MTMALRVTTDVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILRE QGQENLHLEMHQVFRELGPIFRHSVGKTQIVFVTLPEDVEKLYQVESTHPCRMPLESWIV HRELRGLGRGVFLLNGPEWYFNRLQLNPNVLSPKAVQKFVPLVDGIARDFVDNLKKKMLE SVHGSFSMDFQSSVFNYTIEASHFVLFGERLGLIGRDLSPDSLKFLHTLHSMFKTTTQLL YLPRSLTRWTSTRVWKENLESWDFISEYVTKCIKNVYRELAEGRPQSWSVTAELVAERTL SMDAIQANSMELIAGSTDTTSTPLVMTFFELARNPDVQQALRQESLAAEASIAANPQKAM SDLPLLRAALKETLRLYPVGTFLERILSSDLVLQNYHVPAGTVLNVNLYSMGRNPAVFPR PERYMPQRWLERKRSFKHLAFGFGVRQCLGRRLAEAEMMLLLHHVLKSFHVETQEKEDVR MAYRFVLMPSSSPLLTFRPVN

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3TG86-F1 Predicted 1-501 pLDDT 89.0
Metabolism R-MMU-1430728
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000075604
MGI Symbol MGI:88583
NCBI gene (formerly Entrezgene) 110115
UniProtKB Gene Name Q3TG86
WikiGene 110115
CYTOCHROME P450, FAMILY 11, SUBFAMILY B, POLYPEPTIDE 2
Ensembl ID : ENSMUSG00000022589
Gene Symbol: CYP11B2
UniProtKB Entry: P15539
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp11b2|ENSMUSG00000022589
MALRVTADVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQG QENLHLEMHQVFRELGPIFRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHR ELRGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNA RGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSLKFIHALHSMFKSTSQLLFL PKSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLP LDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQESLAAEASIAANPQKAMS DLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLVLLYLYSMGRNPAVFPRP ERYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQM AYRFVLMPSSSPVLTFRPVS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P15539-F1 Predicted 1-500 pLDDT 89.44
Metabolism R-MMU-1430728
Mineralocorticoid biosynthesis R-MMU-193993
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000022589
MGI Symbol MGI:88584
NCBI gene (formerly Entrezgene) 13072
UniProtKB Gene Name P15539
WikiGene 13072
CYTOCHROME P450, FAMILY 4, SUBFAMILY F, POLYPEPTIDE 18
Ensembl ID : ENSMUSG00000003484
Gene Symbol: CYP4F18
UniProtKB Entry: Q99N16
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp4f18|ENSMUSG00000003484
MSQLSMSWMGLGHTAASPWLLLLLAGASCLLAYILTPIYGVFENSLRLRCFPQPPKRNWI LGHLGLIQSSEEGLLYIQSLVRTFRDACCWWVGPLHPVIRIFHPAFIKPVVLAPALVAPK DTVFYRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQR LASKGSAYLNMFEHISLMTLDSLQKCVFSFDSNCQEKPSEYITAILELSTLVARRHQRLL LHVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRRTLLDQGGVDVLKAKAKAKTLDFID VLLLSKDEHGKALSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRE LLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDGRVIPKGVIS RISIFGTHHNPAVWPDPEVYDPFRFDADNVKGRSPLAFIPFSAGPRNCIGQTFAMSEMKV ALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLKVEPLSAGAQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q99N16-F1 Predicted 1-524 pLDDT 91.94
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Eicosanoids R-MMU-211979
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-MMU-2142691
Arachidonate metabolism R-MMU-2142753
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000003484
MGI Symbol MGI:1919304
NCBI gene (formerly Entrezgene) 72054
UniProtKB Gene Name Q99N16
WikiGene 72054
CYTOCHROME P450, FAMILY 8, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000050445
Gene Symbol: CYP8B1
UniProtKB Entry: A0A0R4J0N7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp8b1|ENSMUSG00000050445
MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMR AKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHR MIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAG FLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLS VKQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKH QDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQ EDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYK SGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWG FGTSQPSHEVRFLYRLKPVQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0R4J0N7-F1 Predicted 1-500 pLDDT 91.12
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-MMU-193775
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Eicosanoids R-MMU-211979
Sterols are 12-hydroxylated by CYP8B1 R-MMU-211994
Arachidonate metabolism R-MMU-2142753
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-MMU-2162123
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000050445
MGI Symbol MGI:1338044
NCBI gene (formerly Entrezgene) 13124
UniProtKB Gene Name A0A0R4J0N7
WikiGene 13124
CYTOCHROME P450, FAMILY 1, SUBFAMILY A, POLYPEPTIDE 2
Ensembl ID : ENSMUSG00000032310
Gene Symbol: CYP1A2
UniProtKB Entry: B6VGH4
Assay organism Assay description Assay tissue Bioactivities Reference
MICONAZOLE
Inhibition of CYP1A2 in mouse liver Microsome using phenacetin as substrate in presence of NADPH by LC-MS/MS analysis Liver IC50 = 4550.0 nM

>Cyp1a2|ENSMUSG00000032310
MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNP HLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGK SMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMA EVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPV LRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLI PEEKIVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDR PQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWK DPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFS VPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B6VGH4-F1 Predicted 1-513 pLDDT 93.38
AlphaFold DB AF-P00186-F1 Predicted 1-513 pLDDT 93.81
Metabolism R-MMU-1430728
Phase II - Conjugation of compounds R-MMU-156580
Methylation R-MMU-156581
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 R-MMU-211957
Xenobiotics R-MMU-211981
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of protectins R-MMU-9018681
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Expression Atlas ENSMUSG00000032310
MGI Symbol MGI:88589
NCBI gene (formerly Entrezgene) 13077
UniProtKB Gene Name P00186
UniProtKB Gene Name P00186
WikiGene 13077
CYTOCHROME P450, FAMILY 1, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000032315
Gene Symbol: CYP1A1
UniProtKB Entry: Q05A20
Assay organism Assay description Assay tissue Bioactivities Reference
SULFORAPHANE
Induction of CYP1A1 activity in mouse Hepa-1c1c7 cells assessed as induction ratio at 1 uM after 48 hrs by EROD assay relative to control — Ratio = 0.92 None

>Cyp1a1|ENSMUSG00000032315
MPSMYGLPAFVSATELLLAVTVFCLGFWVVRATRTWVPKGLKTPPGPWGLPFIGHMLTVG KNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLIT NGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQK VMAEVGHFDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADF IPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRKLDE NANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQ PRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNH DRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQ QIEFKVSPGEKVDMTPTYGLTLKHARCEHFQVQMRSSGPQHLQA

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q05A20-F1 Predicted 1-524 pLDDT 91.88
AlphaFold DB AF-P00184-F1 Predicted 1-524 pLDDT 93.12
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of protectins R-MMU-9018681
Expression Atlas ENSMUSG00000032315
MGI Symbol MGI:88588
NCBI gene (formerly Entrezgene) 13076
UniProtKB Gene Name Q05A20
UniProtKB Gene Name Q05A20
WikiGene 13076
CYTOCHROME P450, FAMILY 21, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000024365
Gene Symbol: CYP21A1
UniProtKB Entry: A0A0R4J048
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp21a1|ENSMUSG00000024365
MLLPGLLLLLLLLAGTRWLWGQWKLRKLHLPPLAPGFLHFLQPNLPIYLLGLTQKLGPIY RIRLGMQDVVVLNSNRTIEEALIQKWVDFAGRPHMLNGKMDLDLSLGDYSLMWKAHKKLS RSALMLGMRDSMEPLIEQLTQEFCERMRAQAGTPVAIHKEFSFLTCSIISCLTFGDKDST LVQTLHDCVQDLLQAWNHWSIQILTIIPLLRFLPNPGLQKLKQIQESRDHIVKQQLKRHK DSLVAGQWKDMIDYMLQGVEKQRDGKDEERLHEGHVHMSVVDLFIGGTETTATTLSWAVA FLLHHPEIQKRLQEELDLKLGPGSQLLYRNRMQLPLLMATIAEVLRLRPVVPLALPHRAT RASSISGYDIPKDMVIIPNIQGANLDEMVWELPSKFWPDRFLEPGKNPRTPSFGCGARVC LGEPLARLELFVVLARLLQAFTLLPPPDGTLPSLQPQPYAGINLPIPPFQVRLQPRNLAP QDQGERP

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0R4J048-F1 Predicted 1-487 pLDDT 88.88
Metabolism R-MMU-1430728
Mineralocorticoid biosynthesis R-MMU-193993
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000024365
MGI Symbol MGI:88591
NCBI gene (formerly Entrezgene) 13079
UniProtKB Gene Name A0A0R4J048
WikiGene 13079
CYTOCHROME P450, FAMILY 2, SUBFAMILY W, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000029541
Gene Symbol: CYP2W1
UniProtKB Entry: A0A0G2JFE3
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2w1|ENSMUSG00000029541
MALLLLGVWGILLLLGLWGLLQGCTRSPSLAPRWPPGPRPLPFLGNLHLLGVTQQDRALM ELSERYGPMFTIHLGSQKTVVLSGYEVVREALVGTGHELADRPPIPIFQHIQRGGGIFFS SGARWRAGRQFTVRTLQSLGVQQPSMVGKVLQELACLKGQLDSYGGQPLPLALLGWAPCN ITFTLLFGQRFDYQDPVFVSLLSLIDQVMVLLGSPGIQLFNTFPRLGAFLRLHRPVLSKI EEVRTILRTLLETRRPPLPTGGPAQSYVEALLQQGQEDDPEDMFGEANVLACTLDMVMAG TETTAATLQWAVFLMVKHPHVQGRVQEELDRVLGPGQLPQPEHQRALPYTSAVLHEVQRY ITLLPHVPRCTAADIQLGGYLLPKGTPVIPLLTSVLLDKTQWETPSQFNPNHFLDAKGRF MKRGAFLPFSAGRRVCVGKSLARTELFLLFAGLLQRYRLLPPPGLSPADLDLRPAPAFTM RPPAQTLCVVPRS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q816-F1 Predicted 1-493 pLDDT 92.31
AlphaFold DB AF-A0A0G2JFE3-F1 Predicted 1-200 pLDDT 89.62
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Expression Atlas ENSMUSG00000029541
MGI Symbol MGI:3616076
NCBI gene (formerly Entrezgene) 545817
UniProtKB Gene Name E9Q816
UniProtKB Gene Name E9Q816
WikiGene 545817
CYTOCHROME P450, FAMILY 2, SUBFAMILY F, POLYPEPTIDE 2
Ensembl ID : ENSMUSG00000052974
Gene Symbol: CYP2F2
UniProtKB Entry: P33267
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2f2|ENSMUSG00000052974
MDGVSTAILLLLLAVISLSLTFSSRGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSK EYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGER WKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIIC SVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGG MKDLIARSVREHQDSLDPNSPRDFIDCFLTKMAQEKQDPLSHFNMDTLLMTTHNLLFGGT ETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFA DVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSF KKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPEDIDLTPLSSGLGNL PRPFQLCMHIR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P33267-F1 Predicted 1-491 pLDDT 93.62
AlphaFold DB AF-A0A0U1RPL9-F1 Predicted 1-208 pLDDT 82.31
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000052974
MGI Symbol MGI:88608
NCBI gene (formerly Entrezgene) 13107
UniProtKB Gene Name P33267
UniProtKB Gene Name P33267
WikiGene 13107
CYTOCHROME P450, FAMILY 2, SUBFAMILY T, POLYPEPTIDE 4
Ensembl ID : ENSMUSG00000078787
Gene Symbol: CYP2T4
UniProtKB Entry: D3Z7F6
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2t4|ENSMUSG00000078787
MERARHDRMVTCLALLLLLLILMLLLWWGGVVRRQAQMQKDLPPGPAPLPLLGNLLQLQS GDLDRVLMELSSHWGPVFTVWLGPLPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRFT CGNGIVFSNGPRWHSLRNFALGVLRELGVGRSTIEDRILEEAACVLDEFQATMGAPFDPQ QLLDSAVSNVICTVVFGKRYDYGDPEFRRLLNLFSDNFCIMSSRWAEIYNMFPSFMDWIP GPHNRIFKNFQELRLFISEQIQWHWQSRQTGEPRDFIDCFLDQMDKEQQDLESHFQDETL VMTTHDLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTWAPRIEDRARLPY TNAVLHEIQRFISVLPLGLPRALTRDVNLKNHFLHKGTFVIPLLVSAHRDPTQFKDPDHF NPTNFLDDHGEFQNNDAFMPFALGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPANI NLNPQCTGLGNVPPAFQLRLVAR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9PWV0-F1 Predicted 1-503 pLDDT 94.19
AlphaFold DB AF-D3Z7F6-F1 Predicted 1-495 pLDDT 94.12
Expression Atlas ENSMUSG00000078787
MGI Symbol MGI:2686296
NCBI gene (formerly Entrezgene) 384724
UniProtKB Gene Name E9PWV0
UniProtKB Gene Name E9PWV0
WikiGene 384724
CYTOCHROME P450, FAMILY 27, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000026170
Gene Symbol: CYP27A1
UniProtKB Entry: Q9DBG1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp27a1|ENSMUSG00000026170
MAAWSRTRLRWTLLDPRVVGRGLCPQGARAKATIPAALQAQESTEGPGTGQDRPRLRSPA ELPGTGTLQFLFQLFLQGYVLHLPDLQVLNKTKYGPMWTTSFGTYTNVNLASAPLLEQVM RQEGKYPIRDHMDQWKDHRDHKGLTYGIFIAQGEQWYHLRQALKQRLLKPDEAALYTDAL NEVISDFITRLDQVRAESESGDQVPDMAHLLYHLALEAITYILFEKRIGCLKPSIPEDTA AFIRSVAIMFQNSVYITFLPKWTRPLLPFWKRYLNGWDNIFSFGKKLIDEKVQELKAQLQ ETGPDGVRVSGYLHFLLTNELLSTQETIGTFPELLLAGVDTTSNTLTWALYHLSKSPEIQ EALHKEVTGVVPFGKVPQHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFL FPKNTQFVLCHYVVSRDPSVFPEPNSFQPHRWLRKKEADNPGILHPFGSVPFGYGVRSCL GRRIAELEMQLMLSRLVQKYEIALAPGMGEVKTVSRIVLVPSKKVRLHFLQRQ

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9DBG1-F1 Predicted 1-533 pLDDT 86.94
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-MMU-193775
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000026170
MGI Symbol MGI:88594
NCBI gene (formerly Entrezgene) 104086
UniProtKB Gene Name Q9DBG1
WikiGene 104086
CYTOCHROME P450, FAMILY 2, SUBFAMILY E, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000025479
Gene Symbol: CYP2E1
UniProtKB Entry: Q0PGA1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2e1|ENSMUSG00000025479
MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKL AKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP TWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVI ADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVS EIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAG TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRF INLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGS IPREFKLCVIPRS

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q0PGA1-F1 Predicted 1-333 pLDDT 86.44
AlphaFold DB AF-0000000002145476 Predicted 1-493 pLDDT 92.1
AlphaFold DB AF-A0A1B0GSV7-F1 Predicted 1-434 pLDDT 90.94
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Paracetamol ADME R-MMU-9753281
Expression Atlas ENSMUSG00000025479
MGI Symbol MGI:88607
NCBI gene (formerly Entrezgene) 13106
UniProtKB Gene Name Q0PGA1
UniProtKB Gene Name Q0PGA1
UniProtKB Gene Name Q0PGA1
WikiGene 13106
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 13
Ensembl ID : ENSMUSG00000029727
Gene Symbol: CYP3A13
UniProtKB Entry: Q3UW87
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a13|ENSMUSG00000029727
MDLIPNFSMETWMLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQKGFWEC DIQCHKKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISI SENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYS MDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSL FPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSV IFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVV NETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFS KKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQ GLLQPENPLLLKVVSRDETVSDE

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3UW87-F1 Predicted 1-503 pLDDT 91.44
AlphaFold DB AF-Q64464-F1 Predicted 1-503 pLDDT 91.12
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000029727
MGI Symbol MGI:88610
NCBI gene (formerly Entrezgene) 13113
UniProtKB Gene Name Q64464
UniProtKB Gene Name Q64464
WikiGene 13113
CYTOCHROME P450, FAMILY 24, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000038567
Gene Symbol: CYP24A1
UniProtKB Entry: Q3TWW0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp24a1|ENSMUSG00000038567
MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPG PTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYR TESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKIN EVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIA AIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQPGAD FLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVL PDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQ VLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWII QKYNIVATDSEPVEMLHLGILVPSRELPIAFCPR

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-0000000203481008 Predicted 1-514 pLDDT 79.03
AlphaFold DB AF-Q3TWW0-F1 Predicted 1-514 pLDDT 88.88
Metabolism R-MMU-1430728
Vitamin D (calciferol) metabolism R-MMU-196791
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000038567
MGI Symbol MGI:88593
NCBI gene (formerly Entrezgene) 13081
UniProtKB Gene Name Q64441
UniProtKB Gene Name Q64441
WikiGene 13081
CYTOCHROME P450, FAMILY 51
Ensembl ID : ENSMUSG00000001467
Gene Symbol: CYP51
UniProtKB Entry: Q8K0C4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp51|ENSMUSG00000001467
MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKS PPHIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNS KNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAK EYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWL LPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDEE ISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDL NLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLD FNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFP TVNYTTMIHTPENPVIRYKRRSK

Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q8K0C4-F1 Predicted 1-503 pLDDT 90.81
Metabolism R-MMU-1430728
Cholesterol biosynthesis R-MMU-191273
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000001467
MGI Symbol MGI:106040
NCBI gene (formerly Entrezgene) 13121
UniProtKB Gene Name Q8K0C4
WikiGene 13121