CYTOCHROME P450, FAMILY 27, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000026170
Gene Symbol: CYP27A1
UniProtKB Entry: Q9DBG1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp27a1|ENSMUSG00000026170
MAAWSRTRLRWTLLDPRVVGRGLCPQGARAKATIPAALQAQESTEGPGTGQDRPRLRSPA ELPGTGTLQFLFQLFLQGYVLHLPDLQVLNKTKYGPMWTTSFGTYTNVNLASAPLLEQVM RQEGKYPIRDHMDQWKDHRDHKGLTYGIFIAQGEQWYHLRQALKQRLLKPDEAALYTDAL NEVISDFITRLDQVRAESESGDQVPDMAHLLYHLALEAITYILFEKRIGCLKPSIPEDTA AFIRSVAIMFQNSVYITFLPKWTRPLLPFWKRYLNGWDNIFSFGKKLIDEKVQELKAQLQ ETGPDGVRVSGYLHFLLTNELLSTQETIGTFPELLLAGVDTTSNTLTWALYHLSKSPEIQ EALHKEVTGVVPFGKVPQHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFL FPKNTQFVLCHYVVSRDPSVFPEPNSFQPHRWLRKKEADNPGILHPFGSVPFGYGVRSCL GRRIAELEMQLMLSRLVQKYEIALAPGMGEVKTVSRIVLVPSKKVRLHFLQRQ

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9DBG1-F1 Predicted 1-533 pLDDT 86.94
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-MMU-193775
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000026170
MGI Symbol MGI:88594
NCBI gene (formerly Entrezgene) 104086
UniProtKB Gene Name Q9DBG1
WikiGene 104086
CYTOCHROME P450, FAMILY 2, SUBFAMILY E, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000025479
Gene Symbol: CYP2E1
UniProtKB Entry: Q0PGA1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2e1|ENSMUSG00000025479
MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKL AKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP TWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVI ADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVS EIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAG TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRF INLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGS IPREFKLCVIPRS

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q0PGA1-F1 Predicted 1-333 pLDDT 86.44
AlphaFold DB AF-0000000002145476 Predicted 1-493 pLDDT 92.1
AlphaFold DB AF-A0A1B0GSV7-F1 Predicted 1-434 pLDDT 90.94
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Paracetamol ADME R-MMU-9753281
Expression Atlas ENSMUSG00000025479
MGI Symbol MGI:88607
NCBI gene (formerly Entrezgene) 13106
UniProtKB Gene Name Q0PGA1
UniProtKB Gene Name Q0PGA1
UniProtKB Gene Name Q0PGA1
WikiGene 13106
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 13
Ensembl ID : ENSMUSG00000029727
Gene Symbol: CYP3A13
UniProtKB Entry: Q3UW87
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a13|ENSMUSG00000029727
MDLIPNFSMETWMLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQKGFWEC DIQCHKKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISI SENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYS MDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSL FPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSV IFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVV NETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFS KKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQ GLLQPENPLLLKVVSRDETVSDE

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q3UW87-F1 Predicted 1-503 pLDDT 91.44
AlphaFold DB AF-Q64464-F1 Predicted 1-503 pLDDT 91.12
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000029727
MGI Symbol MGI:88610
NCBI gene (formerly Entrezgene) 13113
UniProtKB Gene Name Q64464
UniProtKB Gene Name Q64464
WikiGene 13113
CYTOCHROME P450, FAMILY 24, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000038567
Gene Symbol: CYP24A1
UniProtKB Entry: Q3TWW0
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp24a1|ENSMUSG00000038567
MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPG PTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYR TESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKIN EVLADFMGQIDELRDERGRIQDLYSELNKWSFESICLVLYEKRFGLLQKDTEEEALTFIA AIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDHRLERYSQQPGAD FLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVL PDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQ VLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWII QKYNIVATDSEPVEMLHLGILVPSRELPIAFCPR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-0000000203481008 Predicted 1-514 pLDDT 79.03
AlphaFold DB AF-Q3TWW0-F1 Predicted 1-514 pLDDT 88.88
Metabolism R-MMU-1430728
Vitamin D (calciferol) metabolism R-MMU-196791
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000038567
MGI Symbol MGI:88593
NCBI gene (formerly Entrezgene) 13081
UniProtKB Gene Name Q64441
UniProtKB Gene Name Q64441
WikiGene 13081
CYTOCHROME P450, FAMILY 51
Ensembl ID : ENSMUSG00000001467
Gene Symbol: CYP51
UniProtKB Entry: Q8K0C4
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp51|ENSMUSG00000001467
MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKS PPHIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNS KNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAK EYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWL LPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDEE ISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDL NLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLD FNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFP TVNYTTMIHTPENPVIRYKRRSK

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q8K0C4-F1 Predicted 1-503 pLDDT 90.81
Metabolism R-MMU-1430728
Cholesterol biosynthesis R-MMU-191273
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000001467
MGI Symbol MGI:106040
NCBI gene (formerly Entrezgene) 13121
UniProtKB Gene Name Q8K0C4
WikiGene 13121