CYTOCHROME P450, FAMILY 1, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000032315
Gene Symbol: CYP1A1
UniProtKB Entry: Q05A20
Assay organism Assay description Assay tissue Bioactivities Reference
SULFORAPHANE
Induction of CYP1A1 activity in mouse Hepa-1c1c7 cells assessed as induction ratio at 1 uM after 48 hrs by EROD assay relative to control — Ratio = 0.92 None

>Cyp1a1|ENSMUSG00000032315
MPSMYGLPAFVSATELLLAVTVFCLGFWVVRATRTWVPKGLKTPPGPWGLPFIGHMLTVG KNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLIT NGKSMTFNPDSGPVWAARRRLAQNALKSFSIASDPTSASSCYLEEHVSKEANYLVSKLQK VMAEVGHFDPYKYLVVSVANVICAICFGQRYDHDDQELLSIVNLSNEFGEVTGSGYPADF IPVLRYLPNSSLDAFKDLNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRKLDE NANVQLSDDKVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQ PRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNH DRELWGDPNEFRPERFLTPSGTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQ QIEFKVSPGEKVDMTPTYGLTLKHARCEHFQVQMRSSGPQHLQA

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q05A20-F1 Predicted 1-524 pLDDT 91.88
AlphaFold DB AF-P00184-F1 Predicted 1-524 pLDDT 93.12
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-MMU-2142670
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of protectins R-MMU-9018681
Expression Atlas ENSMUSG00000032315
MGI Symbol MGI:88588
NCBI gene (formerly Entrezgene) 13076
UniProtKB Gene Name Q05A20
UniProtKB Gene Name Q05A20
WikiGene 13076
CYTOCHROME P450, FAMILY 21, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000024365
Gene Symbol: CYP21A1
UniProtKB Entry: A0A0R4J048
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp21a1|ENSMUSG00000024365
MLLPGLLLLLLLLAGTRWLWGQWKLRKLHLPPLAPGFLHFLQPNLPIYLLGLTQKLGPIY RIRLGMQDVVVLNSNRTIEEALIQKWVDFAGRPHMLNGKMDLDLSLGDYSLMWKAHKKLS RSALMLGMRDSMEPLIEQLTQEFCERMRAQAGTPVAIHKEFSFLTCSIISCLTFGDKDST LVQTLHDCVQDLLQAWNHWSIQILTIIPLLRFLPNPGLQKLKQIQESRDHIVKQQLKRHK DSLVAGQWKDMIDYMLQGVEKQRDGKDEERLHEGHVHMSVVDLFIGGTETTATTLSWAVA FLLHHPEIQKRLQEELDLKLGPGSQLLYRNRMQLPLLMATIAEVLRLRPVVPLALPHRAT RASSISGYDIPKDMVIIPNIQGANLDEMVWELPSKFWPDRFLEPGKNPRTPSFGCGARVC LGEPLARLELFVVLARLLQAFTLLPPPDGTLPSLQPQPYAGINLPIPPFQVRLQPRNLAP QDQGERP

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0R4J048-F1 Predicted 1-487 pLDDT 88.88
Metabolism R-MMU-1430728
Mineralocorticoid biosynthesis R-MMU-193993
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000024365
MGI Symbol MGI:88591
NCBI gene (formerly Entrezgene) 13079
UniProtKB Gene Name A0A0R4J048
WikiGene 13079
CYTOCHROME P450, FAMILY 2, SUBFAMILY W, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000029541
Gene Symbol: CYP2W1
UniProtKB Entry: A0A0G2JFE3
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2w1|ENSMUSG00000029541
MALLLLGVWGILLLLGLWGLLQGCTRSPSLAPRWPPGPRPLPFLGNLHLLGVTQQDRALM ELSERYGPMFTIHLGSQKTVVLSGYEVVREALVGTGHELADRPPIPIFQHIQRGGGIFFS SGARWRAGRQFTVRTLQSLGVQQPSMVGKVLQELACLKGQLDSYGGQPLPLALLGWAPCN ITFTLLFGQRFDYQDPVFVSLLSLIDQVMVLLGSPGIQLFNTFPRLGAFLRLHRPVLSKI EEVRTILRTLLETRRPPLPTGGPAQSYVEALLQQGQEDDPEDMFGEANVLACTLDMVMAG TETTAATLQWAVFLMVKHPHVQGRVQEELDRVLGPGQLPQPEHQRALPYTSAVLHEVQRY ITLLPHVPRCTAADIQLGGYLLPKGTPVIPLLTSVLLDKTQWETPSQFNPNHFLDAKGRF MKRGAFLPFSAGRRVCVGKSLARTELFLLFAGLLQRYRLLPPPGLSPADLDLRPAPAFTM RPPAQTLCVVPRS

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q816-F1 Predicted 1-493 pLDDT 92.31
AlphaFold DB AF-A0A0G2JFE3-F1 Predicted 1-200 pLDDT 89.62
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Expression Atlas ENSMUSG00000029541
MGI Symbol MGI:3616076
NCBI gene (formerly Entrezgene) 545817
UniProtKB Gene Name E9Q816
UniProtKB Gene Name E9Q816
WikiGene 545817
CYTOCHROME P450, FAMILY 2, SUBFAMILY F, POLYPEPTIDE 2
Ensembl ID : ENSMUSG00000052974
Gene Symbol: CYP2F2
UniProtKB Entry: P33267
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2f2|ENSMUSG00000052974
MDGVSTAILLLLLAVISLSLTFSSRGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSK EYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGER WKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIIC SVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGG MKDLIARSVREHQDSLDPNSPRDFIDCFLTKMAQEKQDPLSHFNMDTLLMTTHNLLFGGT ETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFA DVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSF KKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPEDIDLTPLSSGLGNL PRPFQLCMHIR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P33267-F1 Predicted 1-491 pLDDT 93.62
AlphaFold DB AF-A0A0U1RPL9-F1 Predicted 1-208 pLDDT 82.31
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000052974
MGI Symbol MGI:88608
NCBI gene (formerly Entrezgene) 13107
UniProtKB Gene Name P33267
UniProtKB Gene Name P33267
WikiGene 13107
CYTOCHROME P450, FAMILY 2, SUBFAMILY T, POLYPEPTIDE 4
Ensembl ID : ENSMUSG00000078787
Gene Symbol: CYP2T4
UniProtKB Entry: D3Z7F6
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2t4|ENSMUSG00000078787
MERARHDRMVTCLALLLLLLILMLLLWWGGVVRRQAQMQKDLPPGPAPLPLLGNLLQLQS GDLDRVLMELSSHWGPVFTVWLGPLPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRFT CGNGIVFSNGPRWHSLRNFALGVLRELGVGRSTIEDRILEEAACVLDEFQATMGAPFDPQ QLLDSAVSNVICTVVFGKRYDYGDPEFRRLLNLFSDNFCIMSSRWAEIYNMFPSFMDWIP GPHNRIFKNFQELRLFISEQIQWHWQSRQTGEPRDFIDCFLDQMDKEQQDLESHFQDETL VMTTHDLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTWAPRIEDRARLPY TNAVLHEIQRFISVLPLGLPRALTRDVNLKNHFLHKGTFVIPLLVSAHRDPTQFKDPDHF NPTNFLDDHGEFQNNDAFMPFALGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPANI NLNPQCTGLGNVPPAFQLRLVAR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9PWV0-F1 Predicted 1-503 pLDDT 94.19
AlphaFold DB AF-D3Z7F6-F1 Predicted 1-495 pLDDT 94.12
Expression Atlas ENSMUSG00000078787
MGI Symbol MGI:2686296
NCBI gene (formerly Entrezgene) 384724
UniProtKB Gene Name E9PWV0
UniProtKB Gene Name E9PWV0
WikiGene 384724