CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 12
Ensembl ID : ENSMUSG00000096852
Gene Symbol: CYP2D12
UniProtKB Entry: B7ZP10
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d12|ENSMUSG00000096852
MELLTGTDLWSVAIFTVIFILLVDLMHRRQSWTSCYPPGPVPWPVLGNLLQVDLNNMPYS LYKLQNRYGDVFSLQMAWKPMVVINRMKAMKEVLLTCGEDTADRPPVPIFEHLGFKPRSQ GMIFAPYGPEWREQRRFSLSSLRNFGLGRKSLEEWVIKEAGHLCDAFTTQAGQYINPNTM LKKATCNVIASLIFARRFEYEDPYLIRMLKVLEDSLTELSGLIPEVINTFPILLHIPRLA DKFLQSQKSFIAIVDNLLTENRTTWDPAQSPRNLTDAFLAEIEKAKGNPESSFNDENLRM VVIDLFTAGILTTSTTLSWALLLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTN AVIHEVQRFGDIVPLHLPRITSRDIEVQDFLIPKGTILLPNMSSVHMDDTVWEKPLRFHP EHFLDAQGHFVKHEAFITFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPQPSD HRVFSIMVAPSPYQLCAVIREQGH

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q8BVD2-F1 Predicted 1-504 pLDDT 92.81
AlphaFold DB AF-A0A2R8VJY6-F1 Predicted 1-158 pLDDT 78.5
AlphaFold DB AF-B7ZP10-F1 Predicted 1-453 pLDDT 80.5
AlphaFold DB AF-A0A2R8VHA2-F1 Predicted 1-92 pLDDT 60.69
Expression Atlas ENSMUSG00000096852
MGI Symbol MGI:88604
NCBI gene (formerly Entrezgene) 380997
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
UniProtKB Gene Name Q8BVD2
WikiGene 380997
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 34
Ensembl ID : ENSMUSG00000094559
Gene Symbol: CYP2D34
UniProtKB Entry: L7N463
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d34|ENSMUSG00000094559
MELLTGTGLWSVAIFTVIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNIPYS LYKLQNRYGDVFSLQMAWKPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQ GVVLASYGPEWREQRQFSVSTLRNFGLGKKSLEEWVTKEAKHLCDAFTARAGQSINPNTM LNNAVCNVIASLIFARRFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFPILLRIPGLA DMVFQSQKTFMAILDNLVTENRTTWDPDQPPRNLADAFLAEIQKAKGNPESSFNDENLCM VVSDLFTAGMVTTSTTLSCALLLMILHPDVQRRVQQEIDAVIGQVRCPEMADQARMPYTN AVIHEVQRFGDIIPLNIPRITSRDIEVQDFLIPKGTILIPNMSSMLKDETVWEKPLRFYP EHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPAGQPQPSD HRIFAIPVAPYPYQVCAIMREQGH

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VHH8-F1 Predicted 1-92 pLDDT 63.28
AlphaFold DB AF-L7N463-F1 Predicted 1-504 pLDDT 91.38
Expression Atlas ENSMUSG00000094559
MGI Symbol MGI:2385022
NCBI gene (formerly Entrezgene) 223706
UniProtKB Gene Name L7N463
UniProtKB Gene Name L7N463
WikiGene 223706
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 40
Ensembl ID : ENSMUSG00000068083
Gene Symbol: CYP2D40
UniProtKB Entry: Q6P8N9
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d40|ENSMUSG00000068083
MELLTGTDLWPVAIFTVIFILLVDLLHRRQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYS FYKVVKMFPIVLRIPGLADKIFPGQKTFLTMVDKLVTEHKRTWDPDQPPRDLTDAFMAEM ETAKGNPESSFNEANLRLVVLDLFGGGIVTTSATLTWALLLMILHPDVQRRVQEEIDEVI GQARRPEMADQARMPYTNAVIHEVQRFADIAPMTLPHRTSCDIEVQGFLIPKGTTLICNL SSVLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMPFSAGRRACLGEPLVRMELFLFFTC LLQRFSFSVPDGQPLPSDYGIYSMVVSPAPYQLCAVVR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q6P8N9-F1 Predicted 1-338 pLDDT 88.38
Expression Atlas ENSMUSG00000068083
MGI Symbol MGI:1919004
NCBI gene (formerly Entrezgene) 71754
UniProtKB Gene Name Q6P8N9
WikiGene 71754
CYTOCHROME P450, FAMILY 2, SUBFAMILY D, POLYPEPTIDE 26
Ensembl ID : ENSMUSG00000022445
Gene Symbol: CYP2D26
UniProtKB Entry: A0A2R8W716
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2d26|ENSMUSG00000022445
MGLLVGDDLWAVVIFTAIFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYS FYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSK GVILAPYGPEWREQRRFSVSTLRDFGLGKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPL LSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLP DKAFPKLNSFIALVNKMLIEHDSTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRI VVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMADQARMPYTN AVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYP EHFLDAQGHFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSD YGIYTMPVTPEPYQLCAVAR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A2R8VI97-F1 Predicted 1-95 pLDDT 79.19
AlphaFold DB AF-A0A2R8W716-F1 Predicted 1-92 pLDDT 60.62
AlphaFold DB AF-A0A0R4IZY2-F1 Predicted 1-500 pLDDT 91.62
Expression Atlas ENSMUSG00000022445
MGI Symbol MGI:1923529
NCBI gene (formerly Entrezgene) 76279
UniProtKB Gene Name A0A2R8W716
UniProtKB Gene Name A0A2R8W716
UniProtKB Gene Name A0A2R8W716
WikiGene 76279
CYTOCHROME P450, FAMILY 7, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000028240
Gene Symbol: CYP7A1
UniProtKB Entry: Q64505
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp7a1|ENSMUSG00000028240
MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQ RKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGN TTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMF EAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAE SLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQ MIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSAS LNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAK TTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLD QSRAGLGILPPLNDIEFKYKLKH

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64505-F1 Predicted 1-503 pLDDT 93.62
Metabolism R-MMU-1430728
Synthesis of bile acids and bile salts R-MMU-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-MMU-193368
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-MMU-193807
Bile acid and bile salt metabolism R-MMU-194068
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000028240
MGI Symbol MGI:106091
NCBI gene (formerly Entrezgene) 13122
UniProtKB Gene Name Q64505
WikiGene 13122