Cytochrome P450 8A1 (PTGIS)
Ensembl ID : ENSG00000124212
Gene: PTGIS
UniProtKB Entry: Q16647

No data availalbe!

>ENSG00000124212|Cytochrome P450 8A1 (PTGIS)
MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP

Identifier Resolution Method Chain Positions Source
3B6H 1.62 Å X-ray A/B 18-500 PDB
2IAG 2.15 Å X-ray A/B 23-500 PDB
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Eicosanoids R-HSA-211979
Arachidonate metabolism R-HSA-2142753
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Expression Atlas ENSG00000124212
GeneCards 9603
HGNC Symbol HGNC:9603
MIM gene 601699
MIM morbid 145500
NCBI gene (formerly Entrezgene) 5740
UniProtKB Gene Name Q16647
WikiGene 5740
Cytochrome P450 8B1
Ensembl ID : ENSG00000180432
Gene: CYP8B1
UniProtKB Entry: Q9UNU6

No data availalbe!

>ENSG00000180432|Cytochrome P450 8B1
MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLGHAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDPLSFGSILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNETMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQAGELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQRLFHKMLSVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQVLGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQEYLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTMPWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE

Identifier Resolution Method Chain Positions Source
7LYX 2.60 Å X-ray A 26-501 PDB
8EOH 2.65 Å X-ray A 26-501 PDB
Metabolism R-HSA-1430728
Synthesis of bile acids and bile salts R-HSA-192105
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Bile acid and bile salt metabolism R-HSA-194068
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Eicosanoids R-HSA-211979
Sterols are 12-hydroxylated by CYP8B1 R-HSA-211994
Arachidonate metabolism R-HSA-2142753
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Fatty acid metabolism R-HSA-8978868
Expression Atlas ENSG00000180432
GeneCards 2653
HGNC Symbol HGNC:2653
MIM gene 602172
NCBI gene (formerly Entrezgene) 1582
UniProtKB Gene Name Q9UNU6
UniProtKB Gene Name Q9UNU6
WikiGene 1582