EcoDrugPlus

CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 29

Ensembl ID : ENSMUSG00000003053
Gene Symbol: CYP2C29
UniProtKB Entry: Q3UT49

	Assay organism	Assay description	Assay tissue	Bioactivities	Reference

>Cyp2c29|ENSMUSG00000003053
MEMETLRKVTTSCLSQPFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGS FPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKT KGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNSF PSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNPRDFIDYYLIKQKQVNHIEQ SEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCM QDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSK EFPNPEMFDPGHFLNGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLK SLVHPKEIDITPVMNGFASLPPPYQLCFIPL

Identifier	Resolution	Method	Chain	Positions	Source

Source	Identifier	Method	Positions	confidence_type	Confidence Avg.local score
AlphaFold DB	AF-Q64458-F1	Predicted	1-490	pLDDT	93.19
AlphaFold DB	AF-Q3UT49-F1	Predicted	1-451	pLDDT	90.5
AlphaFold DB	AF-H3BLM0-F1	Predicted	1-120	pLDDT	84.31

Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981


Expression Atlas	ENSMUSG00000003053
MGI Symbol	MGI:103238
NCBI gene (formerly Entrezgene)	13095
UniProtKB Gene Name	Q64458
UniProtKB Gene Name	Q64458
UniProtKB Gene Name	Q64458
WikiGene	13095

Select Keywords:

CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 38

Ensembl ID : ENSMUSG00000032808
Gene Symbol: CYP2C38
UniProtKB Entry: P56655

	Assay organism	Assay description	Assay tissue	Bioactivities	Reference

>Cyp2c38|ENSMUSG00000032808
MDLVTFLVLTLSSLILLSLWRQRSRRGRLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKT YGPVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSW KETRRFTLMTLRNLGMGKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICS IIFQDRFDYKDKDFLMLMKKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNFKYI RSYLLEKVKEHQESLDVTNPRDFIDYFLIKQKQANHIEQAEYSLENLVCTINNLFAAGTE TTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFIN LVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGNFK KSDYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLKSLVHPKDIDMIPFVNGLITLP PHYQLCFIPL

Identifier	Resolution	Method	Chain	Positions	Source

Source	Identifier	Method	Resolution	Positions	confidence_type	Confidence Avg.local score
AlphaFold DB	AF-P56655-F1	Predicted		1-490	pLDDT	93.62


Expression Atlas	ENSMUSG00000032808
MGI Symbol	MGI:1306819
NCBI gene (formerly Entrezgene)	13097
UniProtKB Gene Name	P56655
WikiGene	13097

Select Keywords:

CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 39

Ensembl ID : ENSMUSG00000025003
Gene Symbol: CYP2C39
UniProtKB Entry: P56656

	Assay organism	Assay description	Assay tissue	Bioactivities	Reference

>Cyp2c39|ENSMUSG00000025003
MDLVTFLVLTLSSLILLSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKA YGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRW KEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICS IIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYI RSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQANHIQQAEFSLENLACTINNLFAAGTE TTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFIN LVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNFK KSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALP PHYQVCIIPR

Identifier	Resolution	Method	Chain	Positions	Source

Source	Identifier	Method	Resolution	Positions	confidence_type	Confidence Avg.local score
AlphaFold DB	AF-P56656-F1	Predicted		1-490	pLDDT	93.19


Expression Atlas	ENSMUSG00000025003
MGI Symbol	MGI:1306818
NCBI gene (formerly Entrezgene)	13098
UniProtKB Gene Name	P56656
WikiGene	13098

Select Keywords:

CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 67

Ensembl ID : ENSMUSG00000062624
Gene Symbol: CYP2C67
UniProtKB Entry: Q569X9

	Assay organism	Assay description	Assay tissue	Bioactivities	Reference

>Cyp2c67|ENSMUSG00000062624
MDPFVVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKT YGPVFTLYFGSQPIVVLHGYEAMKEAFIDHGEEFSGRGRFPFFDKVTKGKGIGFSHGNVW KATRVFTINTLRNLGMGKRTIENKVQEEAQWLMKELKKTNGLPCDPQFIIGCAPCNVICS IVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWI KSYLLEKIKEHEESLDVTNPRDFIDYFLIQRCQEKGIEHMEYTIEHLATLVTDLVFGGTE SLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYVD LGPISLVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFK KSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIP PNFQMCFIPVE

Identifier	Resolution	Method	Chain	Positions	Source

Source	Identifier	Method	Resolution	Positions	confidence_type	Confidence Avg.local score
AlphaFold DB	AF-Q569X9-F1	Predicted		1-491	pLDDT	93.06


Expression Atlas	ENSMUSG00000062624
MGI Symbol	MGI:3612288
NCBI gene (formerly Entrezgene)	545288
UniProtKB Gene Name	Q569X9
WikiGene	545288

Select Keywords:

CYTOCHROME P450, FAMILY 2, SUBFAMILY C, POLYPEPTIDE 68

Ensembl ID : ENSMUSG00000074882
Gene Symbol: CYP2C68
UniProtKB Entry: K7N6C2

	Assay organism	Assay description	Assay tissue	Bioactivities	Reference

>Cyp2c68|ENSMUSG00000074882
MDPFVVLVLCLSFLLLLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKI YGPVFTLYFGSQPIVILHGYEAMKEAFIDYGEEFSGRGRIPVFDKVSKGKGIGFSHGNVW KATRVFTVNTLRNLGMGKRTIETKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICS IVFQNRFDYKDKDFLSLIGKVNECTEILSSPECQIFNAVPILIDYCPGSHNKFLKNHTWI KSYLLEKIKEHEESLDVTNPRDFVDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTE TLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYID LGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFK KSDYFMPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIP PNFQMCFIPVE

Identifier	Resolution	Method	Chain	Positions	Source

Source	Identifier	Method	Resolution	Positions	confidence_type	Confidence Avg.local score
AlphaFold DB	AF-K7N6C2-F1	Predicted		1-491	pLDDT	93.25


Expression Atlas	ENSMUSG00000074882
MGI Symbol	MGI:3612287
NCBI gene (formerly Entrezgene)	433247
UniProtKB Gene Name	K7N6C2
WikiGene	433247

Select Keywords:

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 27^th July 2026