CYTOCHROME P450, FAMILY 19, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000032274
Gene Symbol: CYP19A1
UniProtKB Entry: Q3ZAT3
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp19a1|ENSMUSG00000032274
MFLEMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSSSIPGPGYCLGIGPLI SHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHYISRFGSKR GLQCIGMHENGIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTD TSGYVDVLTLMRHIMLDTSNMLFLGIPLDESAIVKKIQGYFNAWQALLIKPNIFFKISWL YRKYERSVKDLKDEIAVLVEKKRHKVSTAEKLEDCMDFATDLIFAERRGDLTKENVNQCI LEMLIAAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVGDRDIKIEDIQNLKVVENFI NESMRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILNIGRMHRLEYFPKPNEFTLENFEK NVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKKNDLSLH PNEDRHLVEIIFSPRNSDKYLQQ

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P28649-F1 Predicted 1-503 pLDDT 91.06
AlphaFold DB AF-Q3ZAT3-F1 Predicted 1-503 pLDDT 90.81
AlphaFold DB AF-A0A1L1SUD6-F1 Predicted 1-436 pLDDT 94.69
Metabolism R-MMU-1430728
Estrogen biosynthesis R-MMU-193144
Metabolism of steroid hormones R-MMU-196071
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Endogenous sterols R-MMU-211976
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000032274
MGI Symbol MGI:88587
NCBI gene (formerly Entrezgene) 13075
UniProtKB Gene Name Q3ZAT3
UniProtKB Gene Name Q3ZAT3
UniProtKB Gene Name Q3ZAT3
WikiGene 13075
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 22
Ensembl ID : ENSMUSG00000091867
Gene Symbol: CYP2A22
UniProtKB Entry: B2RXZ2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2a22|ENSMUSG00000091867
MLGSGLLLVAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQL QEHYGPVFTIHLGPRRVVVLYGYDAVKEALEDNAEEFSGRGEQATFNTLFKGYGVTFSNG ERAKQLRRFSIATLKDFGLGKRGMEERIQEEAGCLIKMLQGTCGAPIDPTMYLSKTVSNV ISSIVFGDRFNYEDKEFLSLLQMMSQMNQFAASPTGQLYDMFHSVMKYLPGPQQQIIKDS HKLEDFMIQKVKHNHSTLDPNSPRGFIDSFLIHMQKEKNFNSEFHMKNLVMTSLNLFFAG SETVSSLLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVIHEIQRF SNFAPLGIPRRITKDTSFRGFFLPKGTDVFPIMGSLMIDPKFFSSPKDFNPQHFLDDKGQ LKKIPAFLPFSIGKRSCLGYSLGKMQLFLFFTTILQNFRFKFPRKLEDINESPKPEGFTR IIPKYTMSFVPI

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-B2RXZ2-F1 Predicted 1-492 pLDDT 92.5
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000091867
MGI Symbol MGI:3648316
NCBI gene (formerly Entrezgene) 233005
UniProtKB Gene Name B2RXZ2
WikiGene 233005
CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 12
Ensembl ID : ENSMUSG00000060407
Gene Symbol: CYP2A12
UniProtKB Entry: P56593
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2a12|ENSMUSG00000060407
MLGSGLLLLAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQL QEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKGYGVAFSNG ERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNV ISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGPQQQIIKDS HKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLNLFFAG SETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRF SNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQ LKKIPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKLEDINESPTPEGFTR IIPKYTMSFVPI

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-P56593-F1 Predicted 1-492 pLDDT 92.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Fatty acids R-MMU-211935
Phase I - Functionalization of compounds R-MMU-211945
Xenobiotics R-MMU-211981
CYP2E1 reactions R-MMU-211999
Expression Atlas ENSMUSG00000060407
MGI Symbol MGI:105055
NCBI gene (formerly Entrezgene) 13085
UniProtKB Gene Name P56593
WikiGene 13085
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 57
Ensembl ID : ENSMUSG00000070419
Gene Symbol: CYP3A57
UniProtKB Entry: G3UX95
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a57|ENSMUSG00000070419
MELIPNLSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWKF DDDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKSITI SEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYS MDVITGTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSI FPRQSMNFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTL IFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVV NESLRLYPVVSRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFS KENKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQ PIFRPEKPIILKFVSRDKPRTGP

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-D3YYZ0-F1 Predicted 1-503 pLDDT 91.62
AlphaFold DB AF-G3UX95-F1 Predicted 1-149 pLDDT 92.81
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000070419
MGI Symbol MGI:3646373
NCBI gene (formerly Entrezgene) 622127
UniProtKB Gene Name G3UX95
UniProtKB Gene Name G3UX95
WikiGene 622127
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 16
Ensembl ID : ENSMUSG00000038656
Gene Symbol: CYP3A16
UniProtKB Entry: Q64481
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a16|ENSMUSG00000038656
MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKF DMECYEKYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISL AKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYS MDVIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICM FPKDSIEFFKKFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQS IIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMV LNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERF SKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSR ELLLQPVKPIVLKVVPRDAVITGA

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q64481-F1 Predicted 1-504 pLDDT 90.69
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000038656
MGI Symbol MGI:106099
NCBI gene (formerly Entrezgene) 13114
UniProtKB Gene Name Q64481
WikiGene 13114