CYTOCHROME P450, FAMILY 27, SUBFAMILY B, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000006724
Gene Symbol: CYP27B1
UniProtKB Entry: E9Q3C2
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp27b1|ENSMUSG00000006724
MTQAVKLASRVFHRIHLPLQLDASLGSRGSESVLRSLSDIPGPSTLSFLAELFCKGGLSR LHELQVHGAARYGPIWSGSFGTLRTVYVADPTLVEQLLRQESHCPERCSFSSWAEHRRRH QRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDNVVRDLVRRLRRQRGRGSGLP GLVLDVAGEFYKFGLESIGAVLLGSRLGCLEAEVPPDTETFIHAVGSVFVSTLLTMAMPN WLHHLIPGPWARLCRDWDQMFAFAQRHVELREGEAAMRNQGKPEEDMPSGHHLTHFLFRE KVSVQSIVGNVTELLLAGVDTVSNTLSWTLYELSRHPDVQTALHSEITAGTRGSCAHPHG TALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDIRVGNYVIPQDTLVSLCHYATSRDPTQ FPDPNSFNPARWLGEGPTPHPFASLPFGFGKRSCIGRRLAELELQMALSQILTHFEVLPE PGALPIKPMTRTVLVPERSINLQFVDR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-E9Q3C2-F1 Predicted 1-135 pLDDT 42.06
AlphaFold DB AF-O35084-F1 Predicted 1-507 pLDDT 86.56
Metabolism R-MMU-1430728
Vitamin D (calciferol) metabolism R-MMU-196791
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Vitamins R-MMU-211916
Phase I - Functionalization of compounds R-MMU-211945
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000006724
MGI Symbol MGI:1098274
NCBI gene (formerly Entrezgene) 13115
UniProtKB Gene Name O35084
UniProtKB Gene Name O35084
WikiGene 13115
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 25
Ensembl ID : ENSMUSG00000029630
Gene Symbol: CYP3A25
UniProtKB Entry: D3Z707
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a25|ENSMUSG00000029630
MELIPNLSIETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTIFNYYDGMWKF DEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITI SEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYS MDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSI FPRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVV NESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFS KENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISRE PIFQPEKPIILKVVSRDKPRTGS

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-O09158-F1 Predicted 1-503 pLDDT 91.56
AlphaFold DB AF-D3Z707-F1 Predicted 1-137 pLDDT 77.62
AlphaFold DB AF-D6RJM4-F1 Predicted 1-149 pLDDT 91.56
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000029630
MGI Symbol MGI:1930638
NCBI gene (formerly Entrezgene) 56388
UniProtKB Gene Name O09158
UniProtKB Gene Name O09158
UniProtKB Gene Name O09158
WikiGene 56388
CYTOCHROME P450, FAMILY 3, SUBFAMILY A, POLYPEPTIDE 59
Ensembl ID : ENSMUSG00000061292
Gene Symbol: CYP3A59
UniProtKB Entry: D3Z2W7
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp3a59|ENSMUSG00000061292
MELIPNLSIETWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGTIFNYFDGMWKF DEDCYKKYGKIWGFYVGPKPILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFLKKSITI SEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYS MDVITGTSFGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIYEMLNLSI FPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVV NESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFS KENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISRE PVFQPEKPIILKVVSRDKPRTAS

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A0G2JE14-F1 Predicted 1-149 pLDDT 90.62
AlphaFold DB AF-D3Z2W7-F1 Predicted 1-503 pLDDT 92.06
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Xenobiotics R-MMU-211981
Aflatoxin activation and detoxification R-MMU-5423646
Metabolism of lipids R-MMU-556833
Biosynthesis of DHA-derived SPMs R-MMU-9018677
Biosynthesis of specialized proresolving mediators (SPMs) R-MMU-9018678
Biosynthesis of maresins R-MMU-9018682
Biosynthesis of maresin-like SPMs R-MMU-9027307
Drug ADME R-MMU-9748784
Aspirin ADME R-MMU-9749641
Atorvastatin ADME R-MMU-9754706
Prednisone ADME R-MMU-9757110
Expression Atlas ENSMUSG00000061292
MGI Symbol MGI:3769707
NCBI gene (formerly Entrezgene) 100041449
UniProtKB Gene Name D3Z2W7
UniProtKB Gene Name D3Z2W7
WikiGene 100041449
CYTOCHROME P450, FAMILY 17, SUBFAMILY A, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000003555
Gene Symbol: CYP17A1
UniProtKB Entry: Q53YJ1
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp17a1|ENSMUSG00000003555
MWELVGLLLLILAYFFWPKSKTPNAKFPRSLPFLPLVGSLPFLPRRGHMHANFFKLQEKY GPIYSLRLGTTTAVIVGHYQLAREVLVKKGKEFSGRPQMVTLGLLSDQGKGVAFADSSSS WQLHRKLVFSTFSLFRDDQKLEKMICQEANSLCDLILTYDGESRDLSTLIFKSVINIICT ICFNISFENKDPILTTIQTFTEGIVDVLGHSDLVDIFPWLKIFPNKNLEMIKEHTKIREK TLVEMFEKCKEKFNSESLSSLTDILIQAKMNAENNNTGEGQDPSVFSDKHILVTVGDIFG AGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVL RIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDRFMPERFLDPT GSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPK VVFLIDPFKVKITVRQAWKDAQVEVST

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-A0A494B9N2-F1 Predicted 1-455 pLDDT 84.88
AlphaFold DB AF-Q53YJ1-F1 Predicted 1-507 pLDDT 92.12
AlphaFold DB AF-P27786-F1 Predicted 1-507 pLDDT 92.69
Metabolism R-MMU-1430728
Androgen biosynthesis R-MMU-193048
Glucocorticoid biosynthesis R-MMU-194002
Metabolism of steroid hormones R-MMU-196071
Metabolism of lipids R-MMU-556833
Metabolism of steroids R-MMU-8957322
Expression Atlas ENSMUSG00000003555
MGI Symbol MGI:88586
NCBI gene (formerly Entrezgene) 13074
UniProtKB Gene Name Q53YJ1
UniProtKB Gene Name Q53YJ1
UniProtKB Gene Name Q53YJ1
WikiGene 13074
CYTOCHROME P450, FAMILY 2, SUBFAMILY U, POLYPEPTIDE 1
Ensembl ID : ENSMUSG00000027983
Gene Symbol: CYP2U1
UniProtKB Entry: Q9CX98
Assay organism Assay description Assay tissue Bioactivities Reference

>Cyp2u1|ENSMUSG00000027983
MSSLGDQRPAAGEQPGARLHVRATGGALLLCLLAVLLGWVWLRRQRACGIPPGPKPRPLV GNFGHLLVPRFLRPQFWLGSGSQTDTVGQHVYLARMARVYGNIFSFFIGHRLVVVLSDFH SVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLS LEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDF MSRGLEICLHSQLFLINICPWFYYLPFGPFKELRQIERDISCFLKNIIREHQESLDASNP QDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDV QKKVHEEIERVIGCDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGF TIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQ LAKMELFLMFVSLMQTFTFALPEGSEKPVMTGRFGLTLAPHPFNVTISKR

Identifier Resolution Method Chain Positions Source
Source Identifier Method Resolution Positions confidence_type Confidence Avg.local score
AlphaFold DB AF-Q9CX98-F1 Predicted 1-530 pLDDT 88.44
Metabolism R-MMU-1430728
Biological oxidations R-MMU-211859
Cytochrome P450 - arranged by substrate type R-MMU-211897
Phase I - Functionalization of compounds R-MMU-211945
Miscellaneous substrates R-MMU-211958
Arachidonate metabolism R-MMU-2142753
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-MMU-2142816
Metabolism of lipids R-MMU-556833
Fatty acid metabolism R-MMU-8978868
Expression Atlas ENSMUSG00000027983
MGI Symbol MGI:1918769
NCBI gene (formerly Entrezgene) 71519
UniProtKB Gene Name Q9CX98
WikiGene 71519