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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mu opioid receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Colorectal Neoplasms; Intervertebral Disc Degeneration; Respiratory Insufficiency; Head and Neck Neoplasms; Neuralgia; Nutrition Disorders; Opioid-Related Disorders; Pre-Eclampsia; Sinusitis; Spinal Cord Injuries; Toothache; Wounds and Injuries; Back Pain; Diabetic Neuropathies; Genital Neoplasms, Female; Hypospadias; Joint Diseases; Kidney Calculi; Low Back Pain; Neck Pain; Neoplasms; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Parkinson Disease; Pruritus; Restless Legs Syndrome; Chronic Pain; Pain; Pain, Postoperative; Substance-Related Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mu opioid receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION; ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sunburn; Rhinitis, Allergic, Seasonal; Cough; Sinusitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mu opioid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PHARMACOLOGY
THERAPEUTIC INDICATION: Low Back Pain; Osteoarthritis, Hip; Osteoarthritis, Knee; Acute Pain; Chronic Pain; Pain; Pain, Postoperative
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Infections; Loiasis; Elephantiasis, Filarial; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Nematode GABA-A receptor positive modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thyroid peroxidase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Dermatomyositis; Glioblastoma; Graves Ophthalmopathy; Hyperthyroidism; Thyroid Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC; ORAL; OTIC; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acne Vulgaris; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Digestive System Diseases; Head and Neck Neoplasms; Herpes Simplex; Hypertriglyceridemia; Inflammation; Leukoplakia, Oral; Neuralgia, Postherpetic; Ulcer; Acute Lung Injury; Adenoma; Barrett Esophagus; Blood Coagulation Disorders; Carotid Stenosis; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Disseminated Intravascular Coagulation; Duodenal Ulcer; Endometrial Neoplasms; Glioblastoma; HIV Infections; Heart Diseases; Hypercholesterolemia; Hypertension, Pulmonary; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lupus Erythematosus, Systemic; Melanoma; Metabolic Syndrome; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Periodontitis; Placental Insufficiency; Pneumonia, Viral; Pregnancy; Prostatic Neoplasms; Rectal Neoplasms; Respiratory Distress Syndrome; Respiratory Insufficiency; Sepsis; Tension-Type Headache; Tobacco Use Disorder; Tuberculosis; Uterine Cervical Neoplasms; Venous Thrombosis; Vitamin D Deficiency; Abortion, Habitual; Acute Chest Syndrome; Acute Coronary Syndrome; Adenomatous Polyposis Coli; Angina, Stable; Aortic Valve Stenosis; Asthma; Atherosclerosis; Atrial Fibrillation; Bipolar Disorder; Blindness; Brain Infarction; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Cataract; Cerebral Infarction; Cerebrovascular Disorders; Colitis, Ulcerative; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Esophageal Neoplasms; Fetal Growth Retardation; Gastrointestinal Hemorrhage; Heart Failure; Hemorrhage; Hypertension; Infertility; Influenza, Human; Intracranial Aneurysm; Intracranial Arteriosclerosis; Ischemia; Ischemic Attack, Transient; Ischemic Stroke; Lipid Metabolism Disorders; Low Back Pain; Macular Degeneration; Meningitis; Mucocutaneous Lymph Node Syndrome; Multiple Myeloma; Multiple Sclerosis; Myocardial Ischemia; Non-ST Elevated Myocardial Infarction; Osteoarthritis; Osteonecrosis; Peptic Ulcer; Peripheral Arterial Disease; Pharyngitis; Pneumonia; Polycythemia Vera; Pre-Eclampsia; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Retinal Artery Occlusion; Retinal Vein Occlusion; Rheumatic Heart Disease; ST Elevation Myocardial Infarction; Schizophrenia; Severe Acute Respiratory Syndrome; Stomach Neoplasms; Stomach Ulcer; Thrombocythemia, Essential; Thrombophilia; Varicose Ulcer; Vascular Diseases; Venous Thromboembolism; Wounds and Injuries; Arthritis; Back Pain; Common Cold; Coronary Artery Disease; Dysmenorrhea; Fever; Headache; Migraine Disorders; Muscle Cramp; Myalgia; Myocardial Infarction; Pain; Spasm; Stroke; Thrombosis; Toothache
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arrhythmias, Cardiac; Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colitis, Ulcerative; Crohn Disease; Tuberculosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Rhinitis, Allergic, Seasonal; Sunburn; Influenza, Human; Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M1 antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Irritable Bowel Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Arachidonate 5-lipoxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY
THERAPEUTIC INDICATION: Glioblastoma; Hypertension, Pulmonary; Intestinal Obstruction; Nausea; Cholangitis, Sclerosing; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cardiovascular Diseases; Acute Lung Injury; Ischemic Stroke; Hypotension; Poliomyelitis; Sepsis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Constipation; Hepatitis B, Chronic; Non-alcoholic Fatty Liver Disease; Respiratory Syncytial Virus Infections; Depressive Disorder; Depressive Disorder, Major; Migraine Disorders; Amyotrophic Lateral Sclerosis; Atrial Fibrillation; Death, Sudden, Cardiac; Multiple Sclerosis; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Rotator Cuff Injuries; Angioedema; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Dermatitis Herpetiformis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis, Seborrheic; Dermatomyositis; Enteritis; Erythema Multiforme; Eye Diseases; Herpes Zoster Ophthalmicus; Hypercalcemia; Hypersensitivity; Iridocyclitis; Iritis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Nephrotic Syndrome; Ophthalmia, Sympathetic; Osteoarthritis; Peptic Ulcer; Pneumonia; Polymyositis; Purpura, Thrombocytopenic, Idiopathic; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Aldehyde dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Fatigue; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Acetylcholinesterase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Orthostatic Intolerance
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Crohn Disease; Gastroparesis; Anxiety; Dementia; Depressive Disorder; Hyperemesis Gravidarum; Migraine with Aura; Migraine without Aura; Nausea; Pain; Schizophrenia; Vertigo; Vomiting; Hypersensitivity; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H2 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphodiesterase 3A inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Urinary Bladder, Neurogenic; Digestive System Diseases