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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bradycardia; Myalgia; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Presbyopia; Mydriasis; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Neoplasms; Rectal Neoplasms; Breast Neoplasms; Cerebral Hemorrhage; Heart Diseases; Heart Failure; Neoplasms; Pre-Eclampsia; Stroke; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Ovarian Neoplasms; Uterine Cervical Neoplasms; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Amidophosphoribosyltransferase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Burkitt Lymphoma; Astrocytoma; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Leukemia, Lymphoid; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Cystitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia; Cocaine-Related Disorders; Leukemia; Lymphoma; Neuroblastoma; Anemia, Sickle Cell; Optic Neuritis; Pancreatic Neoplasms; Polyneuropathies; Sarcoma, Ewing; Thalassemia; Wounds and Injuries; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Epilepsy; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hernias, Diaphragmatic, Congenital; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: SUBCUTANEOUS
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Fanconi Anemia; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Blast Crisis; Bone Marrow Failure Disorders; Burkitt Lymphoma; Carcinoma, Merkel Cell; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Ependymoma; Fibromatosis, Aggressive; Hematologic Neoplasms; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myelomonocytic, Juvenile; Leukemia-Lymphoma, Adult T-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Red-Cell Aplasia, Pure; Retinitis Pigmentosa; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Arthritis, Psoriatic; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoidosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Adenoma; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Breast Neoplasms; Choriocarcinoma; Communicable Diseases; Immune System Diseases; Lung Neoplasms; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Carbonic anhydrase I inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Andersen Syndrome; Diabetes Mellitus, Type 1; Hypotension, Orthostatic; Melanoma; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hemorrhoids
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INTRALYMPHATIC; INTRAUTERINE
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: CANCER; OTHER
THERAPEUTIC INDICATION: Hematologic Neoplasms; Arthritis, Rheumatoid; Crohn Disease; Epidermolysis Bullosa Acquisita; Pancreatic Neoplasms; Sarcoma, Ewing; Scleroderma, Diffuse; Sezary Syndrome; Graft vs Host Disease; Lymphoma; Mycosis Fungoides; Lymphoma, T-Cell; Psoriasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension; Pre-Eclampsia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Adrenoleukodystrophy; Anemia, Sickle Cell; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Immunologic Deficiency Syndromes; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; beta-Thalassemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Sarcoma, Ewing; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Arthritis, Rheumatoid; Cardiovascular Diseases; Colitis, Ulcerative; Crohn Disease; Depressive Disorder, Major; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epilepsy; Essential Hypertension; Hematologic Neoplasms; Hypertriglyceridemia; Ischemic Stroke; Lymphoma; Nausea; Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis; Parkinson Disease; Psoriasis; Thrombophlebitis; Urinary Bladder, Overactive; Antiphospholipid Syndrome; Hemorrhage; Hypertension, Pulmonary; Liver Cirrhosis; Aortic Valve Stenosis; Atherosclerosis; Atrial Fibrillation; Atrial Flutter; Brain Infarction; Cerebral Infarction; Coronary Disease; Heart Diseases; Heart Failure; Idiopathic Pulmonary Fibrosis; Ischemic Attack, Transient; Multiple Sclerosis, Relapsing-Remitting; Myocardial Infarction; Myocardial Ischemia; Peripheral Vascular Diseases; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pulmonary Embolism; Rheumatic Heart Disease; Stroke; Thrombocytopenia; Thromboembolism; Venous Thromboembolism; Venous Thrombosis; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Stroke; Epilepsy; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Sciatica; Temporomandibular Joint Disorders; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Leukemia, Myeloid, Acute; Lipoma; Lymphohistiocytosis, Hemophagocytic; Macular Degeneration; Neoplasms; Alveolitis, Extrinsic Allergic; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Celiac Disease; Colitis; Diabetes Mellitus, Type 2; Giant Cell Arteritis; Granulomatosis with Polyangiitis; HIV Infections; Hemangioma; Hodgkin Disease; Hyperlipoproteinemia Type I; Immunoblastic Lymphadenopathy; Infertility; Leprosy; Lichen Planus; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Melanoma; Microscopic Polyangiitis; Muscular Dystrophy, Duchenne; Pemphigoid, Benign Mucous Membrane; Pituitary ACTH Hypersecretion; Renal Insufficiency, Chronic; Schizophrenia; Scleroderma, Systemic; Sinusitis; Stomatitis, Aphthous; Uveitis; Abortion, Habitual; Adrenal Insufficiency; Anemia, Hemolytic, Autoimmune; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Biliary Atresia; Carcinoma, Hepatocellular; Cataract; Churg-Strauss Syndrome; Croup; Eczema; Endocardial Cushion Defects; Eye Infections; Glaucoma; Glaucoma, Open-Angle; Glomerulonephritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Graves Disease; Headache; Hepatitis, Alcoholic; Hypereosinophilic Syndrome; Hypersensitivity; Idiopathic Pulmonary Fibrosis; Inflammation; Ischemic Stroke; Kidney Diseases; Language Disorders; Leukemia, Biphenotypic, Acute; Lupus Nephritis; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mucocutaneous Lymph Node Syndrome; Multiple Myeloma; Ocular Hypertension; Orbital Pseudotumor; Pemphigus; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Pulpitis; Purpura, Thrombocytopenic, Idiopathic; Purpura, Thrombotic Thrombocytopenic; Red-Cell Aplasia, Pure; Sarcoma; Severe Acute Respiratory Syndrome; Spasms, Infantile; Vestibular Neuronitis; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis Herpetiformis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis, Seborrheic; Dermatomyositis; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Adenocarcinoma; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colitis, Ulcerative; Cystic Fibrosis; Glioma; Hepatitis C; Hepatitis C, Chronic; Hidradenitis Suppurativa; Insulin Resistance; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphangioleiomyomatosis; Melanoma; Multiple Myeloma; Myelodysplastic Syndromes; Osteosarcoma; Ovarian Neoplasms; Retinitis Pigmentosa; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colorectal Neoplasms; Crohn Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glioblastoma; HIV Infections; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lichen Planus; Mastocytosis; Multiple Sclerosis, Chronic Progressive; Neoplasms; Osteoarthritis, Knee; Pancreatic Neoplasms; Porphyria Cutanea Tarda; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Small Cell Lung Carcinoma; Zellweger Syndrome; Abortion, Habitual; Antiphospholipid Syndrome; Arthritis, Rheumatoid; Coronavirus Infections; Giant Cell Arteritis; Graft vs Host Disease; Infections; Influenza, Human; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Osteoarthritis; Pneumonia; Pneumonia, Pneumocystis; Pneumonia, Viral; Pre-Eclampsia; Pregnancy; Respiratory Distress Syndrome; Respiratory Insufficiency; Sarcoidosis, Pulmonary; Severe Acute Respiratory Syndrome; Sjogren's Syndrome; Thrombocytopenia; Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Anxiety Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine transporter releasing agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Attention Deficit Disorder with Hyperactivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pregnancy; Cataract; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL; TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alcoholism; Fatigue; Hypotension, Orthostatic; Neoplasms; Opioid-Related Disorders; Postoperative Complications; Amphetamine-Related Disorders; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Feeding and Eating Disorders; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Anemia, Sickle Cell; Anxiety; Asthenia; Bipolar Disorder; Brain Neoplasms; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Hematologic Neoplasms; Multiple Sclerosis; Tobacco Use Disorder; Attention Deficit Disorder with Hyperactivity; Narcolepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine transporter releasing agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bipolar Disorder; Amphetamine-Related Disorders; Cocaine-Related Disorders; Multiple Sclerosis; Opioid-Related Disorders; Schizophrenia; Stroke; Glioma; Arteriosclerosis; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Obesity; Substance-Related Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus; Fibromyalgia; HIV Infections; Hypotension, Orthostatic; Muscular Atrophy, Spinal
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: MUSCULOSKELETAL; OTHER
THERAPEUTIC INDICATION: Canavan Disease; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Inflammation; Leber Congenital Amaurosis; Lymphoma, B-Cell; Parkinson Disease; Red-Cell Aplasia, Pure; Respiratory Syncytial Virus Infections; AIDS-Associated Nephropathy; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; HIV Infections; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis C; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hypersensitivity; Idiopathic Pulmonary Fibrosis; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Leukemia, Lymphoid; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasms; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pemphigoid, Bullous; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Kidney Diseases; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia-Lymphoma, Adult T-Cell; Lupus Nephritis; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neuroblastoma; Pain; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis Herpetiformis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis, Seborrheic; Dermatomyositis; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior