Trade Names | |
Synonyms | |
Status | |
Molecule Category | Free-form |
ATC | A07EC01 |
UNII | 3XC8GUZ6CB |
EPA CompTox | DTXSID0021256 |
InChI Key | NCEXYHBECQHGNR-QZQOTICOSA-N | |
---|---|---|
Smiles | ||
InChI |
|
Property Name | Value | |
---|---|---|
Molecular Formula | C18H14N4O5S | |
Molecular Weight | 398.4 | |
AlogP | 3.7 | |
Hydrogen Bond Acceptor | 7.0 | |
Hydrogen Bond Donor | 3.0 | |
Number of Rotational Bond | 6.0 | |
Polar Surface Area | 141.31 | |
Molecular species | ACID | |
Aromatic Rings | 3.0 | |
Heavy Atoms | 28.0 |
Mechanism of Action | Action | Reference | |
---|---|---|---|
Arachidonate 5-lipoxygenase inhibitor | INHIBITOR | PubMed PubMed PubMed |
Protein: Arachidonate 5-lipoxygenase Description: Polyunsaturated fatty acid 5-lipoxygenase Organism : Homo sapiens P09917 ENSG00000012779 |
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Protein: Cyclooxygenase Description: Prostaglandin G/H synthase 1 Organism : Homo sapiens P23219 ENSG00000095303 |
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Protein: Cyclooxygenase Description: Prostaglandin G/H synthase 2 Organism : Homo sapiens P35354 ENSG00000073756 |
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Resources | Reference | |
---|---|---|
ChEBI | 9334 | |
ChEMBL | CHEMBL421 | |
DrugBank | DB00795 | |
DrugCentral | 2525 | |
FDA SRS | 3XC8GUZ6CB | |
Human Metabolome Database | HMDB0014933 | |
Guide to Pharmacology | 4840 | |
KEGG | C07316 | |
PDB | SAS | |
SureChEMBL | SCHEMBL4515 | |
ZINC | ZINC000003831490 |