DICYCLOMINE HYDROCHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII CQ903KQA31
EPA CompTox DTXSID0058778

Structure

InChI Key GUBNMFJOJGDCEL-UHFFFAOYSA-N
Smiles CCN(CC)CCOC(=O)C1(C2CCCCC2)CCCCC1.Cl
InChI
InChI=1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H36ClNO2
Molecular Weight 345.96
AlogP 4.4
Hydrogen Bond Acceptor 3.0
Number of Rotational Bond 7.0
Polar Surface Area 29.54
Molecular species BASE
Aromatic Rings 0.0
Heavy Atoms 22.0

Pharmacology

Mechanism of Action Action Reference
Muscarinic acetylcholine receptor M1 antagonist ANTAGONIST ISBN DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 105.33-106.9
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cricetulus griseus
- - - - 105.33-106.9

Target Conservation

Protein: Muscarinic acetylcholine receptor M1
Description: Muscarinic acetylcholine receptor M1
Organism : Homo sapiens
P11229 ENSG00000168539
Protein: Muscarinic acetylcholine receptor M3
Description: Muscarinic acetylcholine receptor M3
Organism : Homo sapiens
P20309 ENSG00000133019

Cross References

Resources Reference
CAS NUMBER 67-92-5
ChEBI 4515
ChEMBL CHEMBL1200479
FDA SRS CQ903KQA31
Guide to Pharmacology 355
KEGG C06951
PubChem 441344
SureChEMBL SCHEMBL41670
ZINC ZINC01530613
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