NOREPINEPHRINE BITARTRATE

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Trade Names	LEVOPHED NOREPINEPHRINE BITARTRATE
Synonyms	Adrenor Aktamin Arterenol, tartrate, monohydrate Binodrenal Levarterenol Bitartrate Levarterenol bitartrate Levophed NSC-169106 Noradrenaline Noradrenaline (as tartrate) Noradrenaline bitartrate Noradrenaline tartrate Norepinephrine Norepinephrine bitartrate Norepinephrine bitartrate in 5% dextrose
Status
Molecule Category	Salt-form
UNII	IFY5PE3ZRW
EPA CompTox	DTXSID2047806
Parent Compound:	NOREPINEPHRINE

Structure


InChI Key	LNBCGLZYLJMGKP-JZGIKJSDSA-N
Smiles	NC[C@H](O)c1ccc(O)c(O)c1.O.O=C(O)C(O)C(O)C(=O)O
InChI	InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;;/m0../s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C12H19NO10
Molecular Weight	337.28
AlogP	0.09
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	2.0
Polar Surface Area	86.71
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	12.0

Pharmacology

Mechanism of Action	Action	Reference
Adrenergic receptor agonist	AGONIST	DailyMed

Cross References

Resources	Reference
CAS NUMBER	108341-18-0
ChEBI	33569
ChEMBL	CHEMBL1434513
FDA SRS	IFY5PE3ZRW
Guide to Pharmacology	505
KEGG	C00547
PDB	LT4
PubChem	3047796
ZINC	ZINC00057624

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

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Last update: Monday, 23^rd March 2026