NOREPINEPHRINE BITARTRATE


Trade Names	LEVOPHED NOREPINEPHRINE BITARTRATE
Synonyms	Adrenor Aktamin Arterenol, tartrate, monohydrate Binodrenal Levarterenol Bitartrate Levarterenol bitartrate Levophed NSC-169106 Noradrenaline Noradrenaline (as tartrate) Noradrenaline bitartrate Noradrenaline tartrate Norepinephrine Norepinephrine bitartrate Norepinephrine bitartrate in 5% dextrose Norepinephrine bitartrate monohydrate Norepinephrine d-bitartrate Norepinephrine hydrochloride
Status
Molecule Category	Salt
UNII	IFY5PE3ZRW
Parent Compound:	NOREPINEPHRINE


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	LNBCGLZYLJMGKP-JZGIKJSDSA-N
Smiles	NC[C@H](O)c1ccc(O)c(O)c1.O.O=C(O)C(O)C(O)C(=O)O
InChI	InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;;/m0../s1

Pharmacology

Mechanism of Action	Action	Reference
Adrenergic receptor agonist	AGONIST	DailyMed

Cross References

Resources	Reference
ChEBI	33569
ChEMBL	CHEMBL1434513
FDA SRS	IFY5PE3ZRW
Guide to Pharmacology	505
KEGG	C00547
PDB	LT4
PubChem	3047796
ZINC	ZINC00057624

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects from the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects from the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).