EcoDrugPlus


Trade Names	WYAMINE SULFATE
Synonyms	Mephentermine sulfate Mephentermine sulfate dihydrate Mephentermine sulphate Mephine NSC-758424 Wyamine Wyamine sulfate Wyamine sulphate
Status
Molecule Category	Salt-form
UNII	580655Z8RR
EPA CompTox	DTXSID1047780

Trade Names

WYAMINE SULFATE

Synonyms

Mephentermine sulfate

Mephentermine sulfate dihydrate

Mephentermine sulphate

Mephine

NSC-758424

Wyamine

Wyamine sulfate

Wyamine sulphate

Status

Molecule Category

Salt-form

UNII

580655Z8RR

EPA CompTox

DTXSID1047780


InChI Key	DNKCFBJMFIUNRS-UHFFFAOYSA-N
Smiles	CNC(C)(C)Cc1ccccc1.CNC(C)(C)Cc1ccccc1.O=S(=O)(O)O
InChI	InChI=1S/2C11H17N.H2O4S/c21-11(2,12-3)9-10-7-5-4-6-8-10;1-5(2,3)4/h24-8,12H,9H2,1-3H3;(H2,1,2,3,4)

InChI Key

DNKCFBJMFIUNRS-UHFFFAOYSA-N

Smiles

CNC(C)(C)Cc1ccccc1.CNC(C)(C)Cc1ccccc1.O=S(=O)(O)O

InChI

InChI=1S/2C11H17N.H2O4S/c2*1-11(2,12-3)9-10-7-5-4-6-8-10;1-5(2,3)4/h2*4-8,12H,9H2,1-3H3;(H2,1,2,3,4)

Property Name	Value
Molecular Formula	C22H36N2O4S
Molecular Weight	424.61
AlogP	2.23
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	3.0
Polar Surface Area	12.03
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	12.0

Property Name

Value

Molecular Formula

C22H36N2O4S

Molecular Weight

424.61

AlogP

2.23

Hydrogen Bond Acceptor

1.0

Hydrogen Bond Donor

1.0

Number of Rotational Bond

3.0

Polar Surface Area

12.03

Molecular species

BASE

Aromatic Rings

1.0

Heavy Atoms

12.0

Mechanism of Action	Action	Reference
Adrenergic receptor agonist	AGONIST	PubMed

Mechanism of Action

Action

Reference

Adrenergic receptor agonist

AGONIST

PubMed

Resources	Reference
CAS NUMBER	1212-72-2
ChEBI	6756
ChEMBL	CHEMBL3184799
FDA SRS	580655Z8RR
Guide to Pharmacology	7222
KEGG	C07889
PubChem	71611
SureChEMBL	SCHEMBL121177
ZINC	ZINC08132748

Resources

Reference

CAS NUMBER

ChEBI

ChEMBL

FDA SRS

Guide to Pharmacology

KEGG

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, Volume 54, Issue D1, 6 January 2026, Pages D1397–D1404, https://doi.org/10.1093/nar/gkaf1251

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 23^rd March 2026

MEPHENTERMINE SULFATE

Structure

Physicochemical Descriptors

Pharmacology

Cross References