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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hodgkin Disease; Lichen Planus; Mycosis Fungoides; Lymphoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Scabies
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dystonic Disorders; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carcinoma, Intraductal, Noninfiltrating; Gliosarcoma; Neoplasms; Pancreatic Neoplasms; Severe Dengue; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; Anemia, Sickle Cell; Brain Diseases; Breast Neoplasms; HIV Infections; Influenza, Human; Lupus Erythematosus, Systemic; Multiple Myeloma; Arthritis, Rheumatoid; Glioblastoma; Malaria, Falciparum; Malaria, Vivax; Pregnancy; Severe Acute Respiratory Syndrome; Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated T-type calcium channel blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial enoyl-[acyl-carrier-protein] reductase inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Digestive System Diseases; Head and Neck Neoplasms; Herpes Simplex; Hypertriglyceridemia; Inflammation; Leukoplakia, Oral; Neuralgia, Postherpetic; Ulcer; Acute Lung Injury; Adenoma; Barrett Esophagus; Blood Coagulation Disorders; Carotid Stenosis; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Disseminated Intravascular Coagulation; Duodenal Ulcer; Endometrial Neoplasms; Glioblastoma; HIV Infections; Heart Diseases; Hypercholesterolemia; Hypertension, Pulmonary; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lupus Erythematosus, Systemic; Melanoma; Metabolic Syndrome; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Periodontitis; Placental Insufficiency; Pneumonia, Viral; Pregnancy; Prostatic Neoplasms; Rectal Neoplasms; Respiratory Distress Syndrome; Respiratory Insufficiency; Sepsis; Tension-Type Headache; Tobacco Use Disorder; Tuberculosis; Uterine Cervical Neoplasms; Venous Thrombosis; Vitamin D Deficiency; Abortion, Habitual; Acute Chest Syndrome; Acute Coronary Syndrome; Adenomatous Polyposis Coli; Angina, Stable; Aortic Valve Stenosis; Asthma; Atherosclerosis; Atrial Fibrillation; Bipolar Disorder; Blindness; Brain Infarction; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Cataract; Cerebral Infarction; Cerebrovascular Disorders; Colitis, Ulcerative; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Esophageal Neoplasms; Fetal Growth Retardation; Gastrointestinal Hemorrhage; Heart Failure; Hemorrhage; Hypertension; Infertility; Influenza, Human; Intracranial Aneurysm; Intracranial Arteriosclerosis; Ischemia; Ischemic Attack, Transient; Ischemic Stroke; Lipid Metabolism Disorders; Low Back Pain; Macular Degeneration; Meningitis; Mucocutaneous Lymph Node Syndrome; Multiple Myeloma; Multiple Sclerosis; Myocardial Ischemia; Non-ST Elevated Myocardial Infarction; Osteoarthritis; Osteonecrosis; Peptic Ulcer; Peripheral Arterial Disease; Pharyngitis; Pneumonia; Polycythemia Vera; Pre-Eclampsia; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Retinal Artery Occlusion; Retinal Vein Occlusion; Rheumatic Heart Disease; ST Elevation Myocardial Infarction; Schizophrenia; Severe Acute Respiratory Syndrome; Stomach Neoplasms; Stomach Ulcer; Thrombocythemia, Essential; Thrombophilia; Varicose Ulcer; Vascular Diseases; Venous Thromboembolism; Wounds and Injuries; Arthritis; Back Pain; Common Cold; Coronary Artery Disease; Dysmenorrhea; Fever; Headache; Migraine Disorders; Muscle Cramp; Myalgia; Myocardial Infarction; Pain; Spasm; Stroke; Thrombosis; Toothache
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC; ORAL; OTIC; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acne Vulgaris; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Death, Sudden, Cardiac; Heart Failure; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thyroid peroxidase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Dermatomyositis; Glioblastoma; Graves Ophthalmopathy; Hyperthyroidism; Thyroid Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Infections; Loiasis; Elephantiasis, Filarial; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Constipation; Hepatitis B, Chronic; Non-alcoholic Fatty Liver Disease; Respiratory Syncytial Virus Infections; Depressive Disorder; Depressive Disorder, Major; Migraine Disorders; Amyotrophic Lateral Sclerosis; Atrial Fibrillation; Death, Sudden, Cardiac; Multiple Sclerosis; Myocardial Infarction; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colitis, Ulcerative; Crohn Disease; Tuberculosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hepatitis B, Chronic; Rhinitis, Allergic, Seasonal; Sunburn; Influenza, Human; Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Arachidonate 5-lipoxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY
THERAPEUTIC INDICATION: Glioblastoma; Hypertension, Pulmonary; Intestinal Obstruction; Nausea; Cholangitis, Sclerosing; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sunburn; Rhinitis, Allergic, Seasonal; Cough; Sinusitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphodiesterase 3A inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Aldehyde dehydrogenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amphetamine-Related Disorders; Fatigue; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Solute carrier family 22 member 11 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alcoholism; Brain Injuries; Diabetes Mellitus, Type 2; Influenza in Birds; Neoplasms; Cellulitis; Heart Failure; Heart Failure, Systolic; Infections; Obesity; Urinary Tract Infections; Gout
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Mucositis; Multiple Sclerosis; Neoplasms; Prostatic Neoplasms; Graves Ophthalmopathy; Myalgia; Thyrotoxicosis; Alzheimer Disease; Chagas Disease; Colorectal Neoplasms; HIV Infections; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Stomatitis; Tuberculosis; Urinary Bladder Neoplasms; Dandruff; Dermatitis, Seborrheic; Pruritus; Tinea
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epilepsy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Crohn Disease; Gastroparesis; Anxiety; Dementia; Depressive Disorder; Hyperemesis Gravidarum; Migraine with Aura; Migraine without Aura; Nausea; Pain; Schizophrenia; Vertigo; Vomiting; Hypersensitivity; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Urinary Bladder, Neurogenic; Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Orthostatic Intolerance
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Presbyopia; Mydriasis; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glucosephosphate Dehydrogenase Deficiency; Obesity; Severe Acute Respiratory Syndrome; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Malaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Neoplasms; Adenocarcinoma; Biliary Tract Diseases; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Nasopharyngeal Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypertension; Hypotension, Orthostatic; Infections; Mucositis; Neoplasms; Orthostatic Intolerance; Ovarian Cysts; Pain; Stomatitis; Acute Lung Injury; Bronchiolitis; Cognitive Dysfunction; Mydriasis; Shock, Septic; Stress Disorders, Post-Traumatic; Common Cold; Eye Diseases; Fecal Incontinence; Hypotension; Influenza, Human; Ischemic Stroke; Respiratory Tract Infections; Rhinitis, Allergic, Seasonal; Stroke; Cardiovascular Diseases; Eye Manifestations; Nasal Obstruction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Infections; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Conjunctivitis, Allergic; Heart Failure; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms; Opioid-Related Disorders; Pancreatitis; Phobic Disorders; Wounds and Injuries; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Dermatitis; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Lymphoma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Asthma; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Nasal Obstruction; Osteoarthritis; Otitis Externa; Pneumonia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bradycardia; Myalgia; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Enoyl-[acyl-carrier-protein] reductase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Melanoma; Acquired Immunodeficiency Syndrome; Diabetic Foot; Meningitis; Tuberculosis, Multidrug-Resistant; Ulcer; HIV Infections; Silicosis; Tuberculosis; Tuberculosis, Pulmonary