EcoDrugPlus


Trade Names	PARADIONE
Synonyms	Isoethadione NSC-760129 Paradione Paramethadione
Status
Molecule Category	Free-form
ATC	N03AC01
UNII	Z615FRW64N
EPA CompTox	DTXSID8023420

Trade Names

PARADIONE

Synonyms

Isoethadione

NSC-760129

Paradione

Paramethadione

Status

Molecule Category

Free-form

ATC

N03AC01

UNII

Z615FRW64N

EPA CompTox

DTXSID8023420


InChI Key	VQASKUSHBVDKGU-UHFFFAOYSA-N
Smiles	CCC1(C)OC(=O)N(C)C1=O
InChI	InChI=1S/C7H11NO3/c1-4-7(2)5(9)8(3)6(10)11-7/h4H2,1-3H3

InChI Key

VQASKUSHBVDKGU-UHFFFAOYSA-N

Smiles

CCC1(C)OC(=O)N(C)C1=O

InChI

InChI=1S/C7H11NO3/c1-4-7(2)5(9)8(3)6(10)11-7/h4H2,1-3H3

Property Name	Value
Molecular Formula	C7H11NO3
Molecular Weight	157.17
AlogP	0.76
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	1.0
Polar Surface Area	46.61
Heavy Atoms	11.0

Property Name

Value

Molecular Formula

C7H11NO3

Molecular Weight

157.17

AlogP

0.76

Hydrogen Bond Acceptor

3.0

Number of Rotational Bond

1.0

Polar Surface Area

46.61

Heavy Atoms

11.0

Mechanism of Action	Action	Reference
Voltage-gated T-type calcium channel blocker	BLOCKER	PubMed PubMed

Mechanism of Action

Action

Reference

Voltage-gated T-type calcium channel blocker

BLOCKER

PubMed PubMed

Resources	Reference
ChEBI	7921
ChEMBL	CHEMBL1100
DrugBank	DB00617
DrugCentral	2059
FDA SRS	Z615FRW64N
Human Metabolome Database	HMDB0014755
Guide to Pharmacology	7261
KEGG	C07411
PharmGKB	PA164748880
PubChem	8280
SureChEMBL	SCHEMBL34857

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

HMDB0014755

Guide to Pharmacology

KEGG

PharmGKB

PubChem

SureChEMBL

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

PARAMETHADIONE

Structure

Physicochemical Descriptors

Pharmacology

Cross References