EcoDrugPlus


Trade Names	TRIDIONE
Synonyms	A 2297 Absentol Epidione J2.519D Minoaleviatin NSC-15799 NSC-169503 Tridione Tridone Trimethadione Trimethadionum Troxidone
Status
Molecule Category	Free-form
ATC	N03AC02
UNII	R7GV3H6FQ4
EPA CompTox	DTXSID9021396

Trade Names

TRIDIONE

Synonyms

A 2297

Absentol

Epidione

J2.519D

Minoaleviatin

NSC-15799

NSC-169503

Tridione

Tridone

Trimethadione

Trimethadionum

Troxidone

Status

Molecule Category

Free-form

ATC

N03AC02

UNII

R7GV3H6FQ4

EPA CompTox

DTXSID9021396


InChI Key	IRYJRGCIQBGHIV-UHFFFAOYSA-N
Smiles	CN1C(=O)OC(C)(C)C1=O
InChI	InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3

InChI Key

IRYJRGCIQBGHIV-UHFFFAOYSA-N

Smiles

CN1C(=O)OC(C)(C)C1=O

InChI

InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3

Property Name	Value
Molecular Formula	C6H9NO3
Molecular Weight	143.14
AlogP	0.37
Hydrogen Bond Acceptor	3.0
Polar Surface Area	46.61
Heavy Atoms	10.0

Property Name

Value

Molecular Formula

C6H9NO3

Molecular Weight

143.14

AlogP

0.37

Hydrogen Bond Acceptor

3.0

Polar Surface Area

46.61

Heavy Atoms

10.0

Mechanism of Action	Action	Reference
Voltage-gated T-type calcium channel blocker	BLOCKER	ISBN PubMed PubMed

Mechanism of Action

Action

Reference

Voltage-gated T-type calcium channel blocker

BLOCKER

ISBN PubMed PubMed

Resources	Reference
ChEBI	9727
ChEMBL	CHEMBL695
DrugBank	DB00347
DrugCentral	2751
FDA SRS	R7GV3H6FQ4
Human Metabolome Database	HMDB0014491
Guide to Pharmacology	7316
PharmGKB	PA164744924
PubChem	5576
SureChEMBL	SCHEMBL28882
ZINC	ZINC000001530710

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

HMDB0014491

Guide to Pharmacology

PharmGKB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

TRIMETHADIONE

Structure

Physicochemical Descriptors

Pharmacology

Cross References