METHAMPHETAMINE HYDROCHLORIDE


Trade Names	DESOXYN METHAMPEX METHAMPHETAMINE HYDROCHLORIDE
Synonyms	Desoxyephedrine hydrochloride Desoxyn Metamfetamine hydrochloride Methampex Methamphetamine hcl Methamphetamine hydrochloride Methamphetamine hydrochloride cii Methylamfetamine hydrochloride NSC-169505
Status
Molecule Category	Salt-form
UNII	997F43Z9CV
EPA CompTox	DTXSID8048864
Parent Compound:	METHAMPHETAMINE


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	TWXDDNPPQUTEOV-FVGYRXGTSA-N
Smiles	CN[C@@H](C)Cc1ccccc1.Cl
InChI	InChI=1S/C10H15N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h3-7,9,11H,8H2,1-2H3;1H/t9-;/m0./s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C10H16ClN
Molecular Weight	185.7
AlogP	1.84
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	3.0
Polar Surface Area	12.03
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	11.0

Bioactivity

Mechanism of Action	Action	Reference
Monoamine transporter inhibitor	INHIBITOR	ISBN Wikipedia

Cross References

Resources	Reference
ChEBI	35340
ChEMBL	CHEMBL1200952
FDA SRS	997F43Z9CV
KEGG	C07164
PDB	B40
PubChem	66124
SureChEMBL	SCHEMBL42100
ZINC	ZINC06021043

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects PREMIER and the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).