EcoDrugPlus


Synonyms	IDS-NP-001 Isonipecaine Meperidine Meperidol Pethanol Pethidine Pethidine dbl Pethidineter Renaudin
Status
Molecule Category	Free-form
UNII	9E338QE28F
EPA CompTox	DTXSID9023253


InChI Key	XADCESSVHJOZHK-UHFFFAOYSA-N
Smiles	CCOC(=O)C1(c2ccccc2)CCN(C)CC1
InChI	InChI=1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3

Property Name	Value
Molecular Formula	C15H21NO2
Molecular Weight	247.34
AlogP	2.21
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	3.0
Polar Surface Area	29.54
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	18.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Potassium channels Voltage-gated potassium channel	-	323.59	-	-	-
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor	700	315-500	-	451	-
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family	-	-	-	412	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	-	500	-	451	-
Rattus norvegicus	700	-	-	412	-

Resources	Reference
ChEBI	6754
ChEMBL	CHEMBL607
DrugBank	DB00454
DrugCentral	1690
FDA SRS	9E338QE28F
Human Metabolome Database	HMDB0014597
Guide to Pharmacology	7221
KEGG	C07128
PharmGKB	PA450369
PubChem	4058
SureChEMBL	SCHEMBL25431
ZINC	ZINC000000001681

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MEPERIDINE

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Physicochemical Descriptors

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