MEPERIDINE HYDROCHLORIDE


Trade Names	DEMEROL MEPERIDINE HYDROCHLORIDE MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE
Synonyms	Demerol Meperidine hcl Meperidine hydrochloride Meperidine hydrochloride cii Meperidine hydrochloride preservative free NIH 10522 NSC-400479 Pamergan Pethidine Pethidine hydrochloride Pethidini hydrochloridum Pethilorfan Spasmodlin
Status
Molecule Category	Salt
UNII	N8E7F7Q170
Parent Compound:	MEPERIDINE


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	WCNLCIJMFAJCPX-UHFFFAOYSA-N
Smiles	CCOC(=O)C1(c2ccccc2)CCN(C)CC1.Cl
InChI	InChI=1S/C15H21NO2.ClH/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13;/h4-8H,3,9-12H2,1-2H3;1H

Pharmacology

Mechanism of Action	Action	Reference
Mu opioid receptor agonist	AGONIST	PubMed


Protein: Mu opioid receptor Description: Mu-type opioid receptor Organism : Homo sapiens P35372 ENSG00000112038

Cross References

Resources	Reference
ChEBI	31984
ChEMBL	CHEMBL1701
FDA SRS	N8E7F7Q170
PubChem	5750
SureChEMBL	SCHEMBL41046

CONTENTS


PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains. Elements of the website have been developed under projects from the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

PREMIER has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information this manuscript contains.

Elements of the website have been developed under projects from the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT is thanked for providing computational resources. Content of the website is provided without guarantee for correctness. Data has been collected and integrated from multiple public sources, for the largest: FDA, HUGO Gene Nomenclature Committee, ChEMBL, IUPHAR/BPS guide to pharmacology, Reactome, UniProt, and Ensembl. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).