MEPERIDINE HYDROCHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII N8E7F7Q170
Parent Compound: MEPERIDINE

Structure

InChI Key WCNLCIJMFAJCPX-UHFFFAOYSA-N
Smiles CCOC(=O)C1(c2ccccc2)CCN(C)CC1.Cl
InChI
InChI=1S/C15H21NO2.ClH/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13;/h4-8H,3,9-12H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H22ClNO2
Molecular Weight 283.8
AlogP 2.21
Hydrogen Bond Acceptor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 29.54
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 18.0

Pharmacology

Mechanism of Action Action Reference
Mu opioid receptor agonist AGONIST PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor
- - - 920-920 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- 610 - 413-413 22
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Rattus norvegicus
- 610 - 413-413 22

Target Conservation

Protein: Mu opioid receptor
Description: Mu-type opioid receptor
Organism : Homo sapiens
P35372 ENSG00000112038

Cross References

Resources Reference
ChEBI 31984
ChEMBL CHEMBL1701
FDA SRS N8E7F7Q170
PubChem 5750
SureChEMBL SCHEMBL41046
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