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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acne Vulgaris; Anemia, Aplastic; Carcinoma, Hepatocellular; Severe Acute Respiratory Syndrome; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alzheimer Disease; Graft vs Host Disease; Leukemia, Myeloid, Acute; Lymphoma; Non-alcoholic Fatty Liver Disease; Pulmonary Disease, Chronic Obstructive; Respiratory Syncytial Virus Infections; Urinary Bladder, Overactive; Blastomycosis; Crohn Disease; Histoplasmosis; Intracranial Hypertension; Premature Birth; Sporotrichosis; Vulvovaginitis; Aspergillosis; Bacterial Infections; Candidemia; Candidiasis, Invasive; Candidiasis, Oral; Coccidioidomycosis; HIV Infections; Infections; Leishmaniasis, Cutaneous; Leukopenia; Mycoses; Neoplasms; Tinea Pedis; Vaginal Discharge; Vaginosis, Bacterial; Candidiasis; Candidiasis, Vulvovaginal; Meningitis, Cryptococcal; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY; IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Carcinoma, Squamous Cell; Condylomata Acuminata; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sleep Wake Disorders; Sleep Initiation and Maintenance Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC; ORAL; OTIC
STATUS: Approved
THERAPEUTIC AREA: ENT; EYE; OTHER; PEDIATRICS; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Hearing Loss; Conjunctivitis, Bacterial; Diabetic Foot; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension; Otitis Media; Pelvic Inflammatory Disease; Tuberculosis, Multidrug-Resistant; Urinary Tract Infections; Bacterial Infections; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Atrial Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: AIDS Dementia Complex; Lymphoma; AIDS-Related Complex; Acquired Immunodeficiency Syndrome; Tuberculosis; HIV Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acute Kidney Injury; Arthritis, Rheumatoid; HIV Infections; Leukemia; Breast Neoplasms; Carcinoma; Fibrosis; Lupus Erythematosus, Systemic; Lymphoma; Mucocutaneous Lymph Node Syndrome; Progeria; Tuberculosis; Tuberculosis, Pulmonary; Carcinoma, Hepatocellular; Diabetes Mellitus; Heart Failure; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemia Type III; Hypertension; Ischemic Stroke; Lipid Metabolism Disorders; Multiple Sclerosis, Relapsing-Remitting; Myocardial Infarction; Myocardial Ischemia; Polycystic Kidney, Autosomal Dominant; Pre-Eclampsia; Renal Insufficiency, Chronic; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glioblastoma; Hepatitis C; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Obesity; Alcoholism; Brain Injuries; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Coccidioidomycosis; Depression, Postpartum; Fragile X Syndrome; Mood Disorders; Panic Disorder; Pruritus; Substance-Related Disorders; Anxiety; Anxiety Disorders; Autistic Disorder; Bipolar Disorder; Dementia; Depressive Disorder, Major; Meningitis, Cryptococcal; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Sleep Initiation and Maintenance Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hydroxyapatite sequestering agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Carotid Stenosis; Peripheral Arterial Disease; Thrombosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Lead chelating agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Blast Crisis; Asperger Syndrome; Autistic Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: HMG-CoA reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Alopecia Areata; Anemia, Sickle Cell; Arthritis, Rheumatoid; Choroideremia; Chronic Pain; Cystic Fibrosis; Endotoxemia; Epilepsy; HIV Infections; Hepatitis B, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Sleep Wake Disorders; Vascular Diseases; Atrial Fibrillation; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cardiomyopathy, Dilated; Carotid Artery Diseases; Cerebral Hemorrhage; Diabetes Mellitus, Type 1; Hypertension, Pulmonary; Intermittent Claudication; Leiomyoma; Lung Neoplasms; Migraine Disorders; Mucositis; Multiple Myeloma; Pancreatic Neoplasms; Pancreatitis; Parkinson Disease; Periodontitis; Peripheral Arterial Disease; Prediabetic State; Prostatic Neoplasms; Rectal Neoplasms; Sepsis; Shock, Septic; Sinusitis; Small Cell Lung Carcinoma; Smith-Lemli-Opitz Syndrome; Smoking Cessation; Urinary Bladder Neoplasms; Uveitis; Vitiligo; Waldenstrom Macroglobulinemia; Acute Coronary Syndrome; Alzheimer Disease; Aortic Valve Stenosis; Asthma; Atherosclerosis; Cholangitis, Sclerosing; Colorectal Neoplasms; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Essential Hypertension; Graves Ophthalmopathy; Hyperlipidemia, Familial Combined; Hypertension; Hypertension, Portal; Hypertriglyceridemia; Inflammation; Influenza, Human; Intestinal Neoplasms; Ischemic Stroke; Lipid Metabolism Disorders; Liver Cirrhosis; Metabolic Syndrome; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myocardial Ischemia; Noonan Syndrome; Optic Neuritis; Pneumonia; Polycystic Ovary Syndrome; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Stomach Neoplasms; Subarachnoid Hemorrhage; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Diabetes Mellitus, Type 2; Dyslipidemias; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Myocardial Infarction; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Severe Acute Respiratory Syndrome; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lupus Erythematosus, Systemic; Nephritis, Hereditary; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypercholesterolemia; Hypertension; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel allosteric antagonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Fragile X Syndrome; Idiopathic Hypersomnia; Narcolepsy; Parkinson Disease; Sleep Initiation and Maintenance Disorders; Alcoholism; Obsessive-Compulsive Disorder; Substance-Related Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Mineralocorticoid receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Cardiovascular Diseases; Diabetes Mellitus; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis; Candidiasis; Eczema; Tinea Pedis; Adrenal Hyperplasia, Congenital; Anemia; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Brain Neoplasms; Bursitis; Conjunctivitis, Allergic; Dermatitis, Atopic; Endocrine System Diseases; Inflammation; Multiple Sclerosis; Neoplasms; Osteoarthritis; Peptic Ulcer; Rhinitis, Allergic; Skin Diseases; Spondylitis; Tenosynovitis; Uveitis, Posterior
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase-2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; RHEUMATOLOGY
THERAPEUTIC INDICATION: Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Colorectal Neoplasms; Muscular Diseases; Pain; Sprains and Strains; Acute Pain; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adenosine deaminase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Kidney Neoplasms; Leukemia; Lymphoma; Graft vs Host Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Anemia; Leukemia, Hairy Cell; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Serotonin 3a (5-HT3a) receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER
THERAPEUTIC INDICATION: Brain Diseases; Brain Injuries; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cytomegalovirus Infections; Cytomegalovirus Retinitis; Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC; ORAL
STATUS: Approved
THERAPEUTIC AREA: EYE; IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Graves Ophthalmopathy; Hemorrhagic Fever, Ebola; Immune System Diseases; Respiratory Distress Syndrome; Sepsis; Toxoplasmosis, Cerebral; Bronchiolitis; Crohn Disease; Dysentery, Bacillary; Gastrointestinal Hemorrhage; Gastroparesis; Multiple Sclerosis; Neoplasms; Obsessive-Compulsive Disorder; Onchocerciasis; Periodontitis; Respiratory Syncytial Virus Infections; Sarcoidosis; Tuberculosis; Whooping Cough; Abdominal Pain; Acne Vulgaris; Arthritis, Reactive; Asthma; Blepharitis; Bronchial Diseases; Bronchiectasis; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Chlamydia Infections; Conjunctivitis, Inclusion; Coronary Disease; Coronavirus Infections; Cough; Diarrhea; Digestive System Diseases; Eye Diseases; Fever; Gonorrhea; Inflammation; Lung Diseases; Malaria; Malaria, Falciparum; Malnutrition; Maxillary Sinusitis; Mycobacterium Infections; Mycobacterium avium-intracellulare Infection; Mycoses; Myocardial Infarction; Neonatal Sepsis; Otitis Media, Suppurative; Pneumonia, Viral; Pregnancy; Premature Birth; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Spotted Fever Group Rickettsiosis; Syphilis; Vomiting; Yaws; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Fibrosis; HIV Infections; Infections; Otitis Media; Pelvic Inflammatory Disease; Pharyngitis; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sinusitis; Sprains and Strains; Tonsillitis; Ulcer; Urethritis; Uterine Cervicitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Sinusitis; Tonsillitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase-2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases