FOSCARNET

/static/temp/default.svg Search structure
Synonyms
Status
Molecule Category Free-form
ATC J05AD01
UNII 364P9RVW4X
EPA CompTox DTXSID0048478

Structure

InChI Key ZJAOAACCNHFJAH-UHFFFAOYSA-N
Smiles O=C(O)P(=O)(O)O
InChI
InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)

Physicochemical Descriptors

Property Name Value
Molecular Formula CH3O5P
Molecular Weight 126.0
AlogP -0.16
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 1.0
Polar Surface Area 94.83
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 7.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- 800-800 400 - -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC34 family of sodium phosphate co-transporters
- - - - 84
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
- - - - 84
Human immunodeficiency virus
- - - - 63
Human immunodeficiency virus 1
- 800-800 400 - 96.46
Rattus norvegicus
- - - -

Cross References

Resources Reference
ChEBI 127780
ChEMBL CHEMBL666
DrugBank DB00529
DrugCentral 1241
FDA SRS 364P9RVW4X
Human Metabolome Database HMDB0014670
Guide to Pharmacology 5497
KEGG C06456
PDB PPF
PharmGKB PA449706
PubChem 3415
SureChEMBL SCHEMBL23633
ZINC ZINC000008101109
CONTENTS