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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dysuria; Pain; Urinary Retention
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: HMG-CoA reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; OTHER
THERAPEUTIC INDICATION: Asthma; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cognitive Dysfunction; Fragile X Syndrome; HIV Infections; Heart Diseases; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia; Hypothyroidism
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human immunodeficiency virus type 1 reverse transcriptase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Severe Combined Immunodeficiency; Castleman Disease; Infections; Leukemia-Lymphoma, Adult T-Cell; Liver Cirrhosis, Biliary; Lymphoma; Lymphoma, AIDS-Related; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; AIDS Dementia Complex; AIDS-Related Complex; Acquired Immunodeficiency Syndrome; Diarrhea; Pneumonia, Pneumocystis; Pregnancy; Severe Acute Respiratory Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Reperfusion Injury; Heart Defects, Congenital; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Muscle Cramp; Shock, Septic; Subarachnoid Hemorrhage; Vasospasm, Intracranial; Heart Failure; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Candidiasis, Vulvovaginal
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bile acid receptor FXR agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus; Heart Failure; Hepatitis D; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Diabetes Mellitus, Type 2; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL; OTIC
STATUS: Approved
THERAPEUTIC AREA: GASTROINTESTINAL; OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Carcinoma, Pancreatic Ductal; Diabetic Foot; Gastroenteritis; Hearing Loss; Hepatitis C; Leukemia, Myeloid, Acute; Lung Diseases; Lymphoma; Neoplasms; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Plague; Abscess; Bacteremia; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dysthymic Disorder; Cocaine-Related Disorders; Epilepsy; Gastroesophageal Reflux; Hypertension, Pulmonary; Ischemic Stroke; Marijuana Abuse; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Obesity; Panic Disorder; Sciatica; Anxiety; Autistic Disorder; Bipolar Disorder; Cerebral Hemorrhage; Dementia; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Enuresis; Fibromyalgia; Influenza, Human; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Stroke; Tobacco Use Disorder; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter releasing agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Opioid receptors; mu/kappa/delta agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Myasthenia Gravis; Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Parkinson Disease; Carotid Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Hypertension; Prostatic Hyperplasia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Bronchitis, Chronic; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Isoleucyl-tRNA synthetase inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY; OTHER
THERAPEUTIC INDICATION: Sinusitis; Cystic Fibrosis; Hemangioma; Radiodermatitis; Epistaxis; Staphylococcal Infections; Telangiectasia, Hereditary Hemorrhagic; Impetigo; Infections; Nasal Obstruction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glioma; Lymphoma; Multiple Myeloma; Sarcoma; Breast Neoplasms; Granuloma, Lethal Midline; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Multiple Sclerosis; Pancreatic Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Peripheral; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase-2 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION; INTRAVENOUS; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Muscular Diseases; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasm Metastasis; Obesity; Osteosarcoma; Primary Myelofibrosis; Stiff-Person Syndrome; Vasculitis; Acute Kidney Injury; Anemia, Aplastic; Anemia, Sickle Cell; Burkitt Lymphoma; Carcinoma, Hepatocellular; Crohn Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuromyelitis Optica; Renal Insufficiency, Chronic; Retinoblastoma; Sarcoma, Ewing; Testicular Neoplasms; Brain Neoplasms; Breast Neoplasms; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Multiple Sclerosis, Relapsing-Remitting; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Scleroderma, Systemic; Thrombocytopenia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Aging; Depressive Disorder; Neoplasms; Periodontitis; Carcinoma; Carcinoma, Basal Cell; Mastodynia; Pulmonary Embolism; Wounds and Injuries; Infertility; Osteoarthritis, Hip; Osteoarthritis, Knee; Renal Colic; Spondylitis, Ankylosing; Stomach Ulcer; Toothache; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Cataract; Dysmenorrhea; Eye Diseases; Inflammation; Keratosis, Actinic; Migraine Disorders; Myalgia; Osteoarthritis; Rheumatic Diseases; Sprains and Strains
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Brain Neoplasms; Aortic Aneurysm, Thoracic; Stroke; Subarachnoid Hemorrhage; Hypertension; Muscle Cramp; Pre-Eclampsia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Breast Neoplasms; Burkitt Lymphoma; Glioma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiopericytoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Mesenchymoma; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cocaine-Related Disorders; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Reducing agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Chemical and Drug Induced Liver Injury; Cystinuria; Subarachnoid Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases; Glaucoma