TERCONAZOLE


Trade Names	TERAZOL 3 TERAZOL 7 TERCONAZOLE
Synonyms	Fungistat Gyno-Terazol NSC-331942 Panlomyc R 42470 R-42,470 R-42470 Terazol Terazol 3 Terazol 7 Terconazole Tercospor Termayazole Triaconazole
Status
Molecule Category	Free-form
ATC	G01AG02
UNII	0KJ2VE664U
EPA CompTox	DTXSID2045498


InChI Key	BLSQLHNBWJLIBQ-OZXSUGGESA-N
Smiles	CC(C)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4cncn4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1
InChI	InChI=1S/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/m0/s1

Property Name	Value
Molecular Formula	C26H31Cl2N5O3
Molecular Weight	532.47
AlogP	4.46
Hydrogen Bond Acceptor	8.0
Number of Rotational Bond	8.0
Polar Surface Area	64.88
Molecular species	NEUTRAL
Aromatic Rings	3.0
Heavy Atoms	36.0

Mechanism of Action	Action	Reference
Cytochrome P450 51 inhibitor	INHIBITOR	PubMed PubMed DailyMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Oxidoreductase	-	410	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Rattus norvegicus	-	410	-	-	-
Trypanosoma cruzi	400	-	-	-	-

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Resources	Reference
ChEBI	82980
ChEMBL	CHEMBL1306
DrugBank	DB00251
FDA SRS	0KJ2VE664U
Human Metabolome Database	HMDB0014396
KEGG	C08080
PharmGKB	PA164768834
PubChem	480953
SureChEMBL	SCHEMBL23165
ZINC	ZINC000003873936

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

TERCONAZOLE

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

Cross References