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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Alpha-1a adrenergic receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Opioid receptors; mu/kappa/delta antagonist
ROUTE OF ADMINISTRATION: INTRAMUSCULAR
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM
THERAPEUTIC INDICATION: Alcohol Drinking; Child Development Disorders, Pervasive; Dermatitis, Atopic; Psoriasis; Schizophrenia; Alcohol-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Colitis, Ulcerative; Coronavirus Infections; Crohn Disease; Cystitis, Interstitial; Depressive Disorder, Major; Diabetic Neuropathies; Dry Eye Syndromes; Fatigue; Fibromyalgia; Low Back Pain; Marijuana Abuse; Migraine Disorders; Obsessive-Compulsive Disorder; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Trichotillomania; Borderline Personality Disorder; Chronic Pain; Cocaine-Related Disorders; Depressive Disorder; Endometriosis; Gambling; HIV Infections; Heroin Dependence; Multiple Sclerosis; Obesity; Opioid-Related Disorders; Pain; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder; Alcoholism
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Prostatic Neoplasms; Adrenal Gland Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pain; Cerebral Hemorrhage; Cocaine-Related Disorders; Sinusitis; Stroke; Tobacco Use Disorder; Hypertension; Pre-Eclampsia; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Constipation; Heart Arrest; Heroin Dependence; Restless Legs Syndrome; Rheumatic Diseases; Blood Coagulation Disorders; Chronic Pain; Fractures, Multiple; Head and Neck Neoplasms; Hemorrhage; Mucositis; Neuralgia; Postoperative Complications; Premature Birth; Respiratory Insufficiency; Rotator Cuff Injuries; Stomatitis; Tonsillitis; Adenocarcinoma; Anemia, Sickle Cell; Back Pain; Dyspnea; Kidney Calculi; Leukemia, Myeloid, Acute; Myocardial Infarction; Neonatal Abstinence Syndrome; Neoplasms; Obesity; Opioid-Related Disorders; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pruritus; Pulmonary Disease, Chronic Obstructive; Renal Colic; Rib Fractures; Scoliosis; Sleep Apnea, Obstructive; Wounds and Injuries; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein 2 inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hematologic Neoplasms; Bacterial Infections; Enterobacteriaceae Infections; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Endocarditis; Infections; Intraabdominal Infections; Pneumonia; Sepsis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Bipolar Disorder; Carcinoma, Non-Small-Cell Lung; Diabetes Mellitus, Type 2; Head and Neck Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Mitochondrial Diseases; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Crohn Disease; Huntington Disease; Marijuana Abuse; Restless Legs Syndrome; Substance-Related Disorders; Anxiety; Attention Deficit Disorder with Hyperactivity; Dementia; Depressive Disorder, Major; Obesity; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Neoplasms; Pulmonary Alveolar Proteinosis; Atherosclerosis; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Epilepsy; HIV Infections; Heart Failure; Lymphoma; Multiple Myeloma; Myocardial Infarction; Myocardial Ischemia; Psychotic Disorders; Tuberculosis, Pulmonary; Alzheimer Disease; Hand-Foot Syndrome; Movement Disorders; Non-alcoholic Fatty Liver Disease; Spasms, Infantile; Tuberculosis; Anemia; Diabetes Mellitus, Type 2; Kidney Failure, Chronic; Osteoporosis; Postoperative Nausea and Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Shock, Septic; Acquired Immunodeficiency Syndrome; Anemia, Sickle Cell; Diabetes Mellitus, Type 2; Heart Failure; Muscle Cramp; Neoplasms; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Spinal Cord Injuries; Acute Kidney Injury; Atrial Fibrillation; Cytomegalovirus Infections; Gastrointestinal Stromal Tumors; HIV Infections; Hyperthyroidism; Lipid Metabolism Disorders; Multiple Sclerosis; Muscular Atrophy, Spinal; Pancreatic Neoplasms; Peripheral Arterial Disease; Pyelonephritis; Sarcopenia; Brain Diseases; Kidney Failure, Chronic; Muscle Weakness
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Supplement
ROUTE OF ADMINISTRATION: INTRAVENOUS
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acne Vulgaris; Ascorbic Acid Deficiency; Asthma; Astrocytoma; Autistic Disorder; Breast Neoplasms; Burns; Carcinoma, Pancreatic Ductal; Colonic Neoplasms; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Gliosarcoma; Hypertension; Hypoxia; Neoplasms; Oligodendroglioma; Osteoarthritis; Polycythemia Vera; Primary Myelofibrosis; Pulmonary Alveolar Proteinosis; Sarcoma; Temporomandibular Joint Disorders; Thrombocythemia, Essential; Urinary Bladder Neoplasms; Acute Lung Injury; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carotid Artery Diseases; Charcot-Marie-Tooth Disease; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsy; Fatigue; Glioblastoma; Heart Arrest; Heart Diseases; Heart Failure; Hodgkin Disease; Inflammation; Intracranial Arteriosclerosis; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Multiple Myeloma; Muscular Diseases; Myelodysplastic Syndromes; Myocardial Infarction; Ovarian Neoplasms; Pancreatic Neoplasms; Pre-Eclampsia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Renal Insufficiency, Chronic; Shock; Stomatitis; Tobacco Use Disorder; Uterine Cervical Neoplasms; Virus Diseases; Wounds and Injuries; beta-Thalassemia; Anorexia; Atrial Fibrillation; Atrial Flutter; Cataract; Colorectal Neoplasms; Complex Regional Pain Syndromes; Diabetes Mellitus; Glioma; Influenza, Human; Leiomyoma; Macular Degeneration; Menopause; Myocardial Ischemia; Pain; Respiratory Distress Syndrome; Respiratory Tract Infections; Schizophrenia; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Stomach Neoplasms; Anemia; Anemia, Iron-Deficiency; Eye Diseases; Kidney Failure, Chronic; Pneumonia; Scurvy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanoma; Neoplasms; Cardiomyopathy, Hypertrophic; Hepatolenticular Degeneration
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Sclerosis; Acidosis, Lactic; Heart Arrest; Huntington Disease; Respiratory Insufficiency; Heart Failure; Hyperemesis Gravidarum; Sepsis; Shock, Septic; Anemia; Brain Diseases; Kidney Failure, Chronic; Thiamine Deficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Erectile Dysfunction; Ischemia; Renal Insufficiency, Chronic; Cerebral Hemorrhage; Diabetes Mellitus, Type 1; Essential Hypertension; Glomerulonephritis, IGA; Heart Diseases; Melanoma; Pseudohypoaldosteronism; Stroke; Cardiomyopathies; Cardiotoxicity; Chagas Cardiomyopathy; Heart Failure; Hypertension; Influenza, Human; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Myocardial Ischemia; Neoplasms; Pneumonia; ST Elevation Myocardial Infarction; Severe Acute Respiratory Syndrome; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cholecystitis; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Glioma; Pituitary Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Diagnostic agent
ROUTE OF ADMINISTRATION: INJECTION; ORAL; RECTAL; URETHRAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Fabry Disease; HIV Infections; Neoplasms; Renal Insufficiency; Acute Kidney Injury; Kidney Diseases; Myocardial Ischemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Renal dipeptidase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sepsis; Hematologic Neoplasms; Infections; Urinary Tract Infections; Bacterial Infections; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amyloidosis, Familial; Hemorrhagic Fever, Ebola; Severe Acute Respiratory Syndrome; Tachycardia, Supraventricular; Atrial Fibrillation; Atrial Flutter; Cardiomyopathies; Death, Sudden, Cardiac; Heart Arrest; Heart Failure; Myocardial Infarction; Tachycardia, Ventricular; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Irritable Bowel Syndrome; Blepharospasm; Charcot-Marie-Tooth Disease; Chronic Pain; Dystonic Disorders; Death, Sudden, Cardiac; Myocardial Infarction; Myotonic Dystrophy; Ventricular Fibrillation; Arrhythmias, Cardiac
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
ROUTE OF ADMINISTRATION: INHALATION; ORAL
STATUS: Approved
THERAPEUTIC AREA: GASTROINTESTINAL; IMMUNE SYSTEM; OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Neoplasms; Diabetes Mellitus, Type 1; Encephalitis, Japanese; Hemorrhagic Fever with Renal Syndrome; Hepatitis D; Influenza, Human; Lassa Fever; Leukemia, Myeloid, Acute; Thrombocytopenia; Depressive Disorder; HIV Infections; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Infections; Respiratory Syncytial Virus Infections; Severe Acute Respiratory Syndrome; Fibrosis; Hepatitis C, Chronic; Liver Cirrhosis; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sleep Initiation and Maintenance Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Anemia, Neonatal; Heart Failure; Huntington Disease; Multiple Sclerosis; Anemia; Anemia, Iron-Deficiency; Diabetes Mellitus, Type 2; Kidney Failure, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Opioid receptors; mu/kappa/delta agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glaucoma, Open-Angle; Ocular Hypertension; Cardiovascular Diseases; Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cystic Fibrosis; Esophageal Achalasia; Meningitis, Bacterial; Enterobacteriaceae Infections; Skin Diseases; Staphylococcal Skin Infections; Bacterial Infections; Infections; Intraabdominal Infections; Parametritis; Peritonitis; Pneumonia; Pyelonephritis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arrhythmogenic Right Ventricular Dysplasia; Atrial Fibrillation; Arrhythmias, Cardiac