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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Infections; Burns
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Potassium channel, inwardly rectifying, subfamily J, member 11 opener
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Depressive Disorder; Diabetes Mellitus, Type 2; Obesity; Adenoma, Islet Cell; Hyperinsulinism; Hypertension; Hypoglycemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-1 agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-2 adrenergic receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Substance-Related Disorders; Asthma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Neoplasms; Seminoma; Testicular Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetic Cardiomyopathies; Heart Failure; Heart Failure, Diastolic; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tubulin inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Glioma; Hookworm Infections; Pruritus; Anemia; Colorectal Neoplasms; Necatoriasis; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Acyl coenzyme A:cholesterol acyltransferase 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Diabetes Mellitus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Carnitine O-palmitoyltransferase 1, muscle isoform inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bile acids sequestering agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Candidiasis, Vulvovaginal; Tinea Pedis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Mastitis; Enterobacteriaceae Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-2 agonist
ROUTE OF ADMINISTRATION: ORAL; TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Brain Ischemia; Cocaine-Related Disorders; Dermatitis, Atopic; Hemorrhage; Heroin Dependence; Hypotension, Orthostatic; Orthostatic Intolerance; Anxiety; Brain Injuries; Breast Neoplasms; Child Development Disorders, Pervasive; Diabetic Neuropathies; Low Back Pain; Marijuana Abuse; Musculoskeletal Diseases; Opioid-Related Disorders; Stomatitis; Substance-Related Disorders; Cardiovascular Diseases; Delirium; Fecal Incontinence; Genital Neoplasms, Male; Hyperemesis Gravidarum; Neonatal Abstinence Syndrome; Pain; Postoperative Complications; Pregnancy; Scoliosis; Stress Disorders, Post-Traumatic; Attention Deficit Disorder with Hyperactivity; Glaucoma; Hypertension; Migraine Disorders; Neoplasms; Neuralgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Thyroid Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: BUCCAL; INJECTION
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Stomatitis; HIV Infections; Infections; Mycoses; Pruritus; Tinea; Tinea Pedis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gram-Positive Bacterial Infections; Mastitis; Enterobacteriaceae Infections; Staphylococcal Infections; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atrophic Vaginitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Matrix metalloproteinase 13 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Neuralgia; Purpura, Thrombocytopenic, Idiopathic; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor modulator
ROUTE OF ADMINISTRATION: INJECTION; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER; PEDIATRICS
THERAPEUTIC INDICATION: Astrocytoma; Brain Neoplasms; Central Serous Chorioretinopathy; Glioblastoma; Obesity; Obesity, Morbid; Postoperative Complications; Syphilis, Congenital; Asthma; Bacteremia; Buruli Ulcer; Chlamydia Infections; Colitis, Ulcerative; Head and Neck Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Mastitis; Periapical Periodontitis; Pneumonia, Bacterial; Pseudomyxoma Peritonei; Tuberculosis; Tuberculosis, Pulmonary; Vaginosis, Bacterial; Abscess; Bronchitis, Chronic; Cholecystitis; Communicable Diseases; Dyspepsia; Endocarditis; Enterobacteriaceae Infections; Fever; Gastritis; Helicobacter Infections; Hemorrhage; Hepatitis, Alcoholic; Influenza, Human; Low Back Pain; Lymphoma, Non-Hodgkin; Malaria, Falciparum; Malnutrition; Neutropenia; Otitis Media, Suppurative; Periodontitis; Pyelonephritis; Severe Acute Respiratory Syndrome; Stomach Ulcer; Urinary Bladder Neoplasms; Bacterial Infections; Duodenal Ulcer; Gonorrhea; Infections; Otitis Media; Pharyngitis; Pneumonia; Respiratory Tract Infections; Sinusitis; Soft Tissue Infections; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor negative allosteric modulator
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lice Infestations; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Refractive Errors; Miosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Carcinoma, Squamous Cell; Hypertension; Laryngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Prostatic Neoplasms; Angina, Stable
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-2 adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INHALATION; INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Pulmonary Disease, Chronic Obstructive; Asthma; Bronchial Spasm; Bronchitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-2 agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; PEDIATRICS
THERAPEUTIC INDICATION: Pain; Attention Deficit Disorder with Hyperactivity; Hypertension