DOPAMINE HYDROCHLORIDE

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Search structure


Trade Names	DOPAMINE HYDROCHLORIDE DOPAMINE HYDROCHLORIDE AND DEXTROSE 5% DOPAMINE HYDROCHLORIDE AND DEXTROSE 5% IN PLASTIC CONTAINER DOPAMINE HYDROCHLORIDE IN DEXTROSE 5% DOPAMINE HYDROCHLORIDE IN DEXTROSE 5% IN PLASTIC CONTAINER INTROPIN
Synonyms	ASL-279 Cardiosteril Dopamin-Natterman Dopamine hcl Dopamine hydrochloride Dopamini hydrochloridum Dopmin Dynatra Inotropin Intropin NSC-169105 Sabax Dopamin Selectajet Tensamin
Status
Molecule Category	Salt-form
UNII	7L3E358N9L
EPA CompTox	DTXSID7020550
Parent Compound:	DOPAMINE

Structure


InChI Key	CTENFNNZBMHDDG-UHFFFAOYSA-N
Smiles	Cl.NCCc1ccc(O)c(O)c1
InChI	InChI=1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C8H12ClNO2
Molecular Weight	189.64
AlogP	0.6
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	2.0
Polar Surface Area	66.48
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	11.0

Pharmacology

Mechanism of Action	Action	Reference
Beta-1 adrenergic receptor agonist	AGONIST	DailyMed Wikipedia

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Dopamine receptor	0.631-37	-	-	2-920	-
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	66.46-73.49

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	66.46-73.49
Homo sapiens	0.631-37	-	-	2-920	-
Phaseolus vulgaris	-	-	-	-	0-26
Rattus norvegicus	-	-	-	4.5-4.7	-

Target Conservation


Protein: Beta-1 adrenergic receptor Description: Beta-1 adrenergic receptor Organism : Homo sapiens P08588 ENSG00000043591

Cross References

Resources	Reference
ChEBI	4698
ChEMBL	CHEMBL1557
FDA SRS	7L3E358N9L
Guide to Pharmacology	940
KEGG	C03758
PDB	LDP
PubChem	65340
SureChEMBL	SCHEMBL40951
ZINC	ZINC00033882

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025