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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Postoperative Nausea and Vomiting; Vertigo; Hypersensitivity; Vomiting
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Alzheimer Disease; Prostatic Neoplasms, Castration-Resistant; Dental Caries; Gingivitis; Sensitivity and Specificity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive modulator
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel protein type IV alpha subunit blocker
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: EMERGENCY MEDICINE; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Aortic Coarctation; Brain Neoplasms; HIV Infections; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Vasospasm, Intracranial; Abdominal Pain; Appendicitis; Atrial Fibrillation; Blepharoptosis; Blood Coagulation Disorders; Cleft Palate; Dupuytren Contracture; Fasciitis, Plantar; Femoral Neck Fractures; Headache; Hemorrhage; Hernia, Umbilical; Hip Fractures; Hypospadias; Hypotension; Lacrimal Apparatus Diseases; Low Back Pain; Lung Neoplasms; Mucositis; Musculoskeletal Diseases; Osteoarthritis, Hip; Osteoarthritis, Knee; Pregnancy; Pulpitis; Rib Fractures; Rotator Cuff Injuries; Sarcoma; Shoulder Pain; Spinal Stenosis; Ankle Fractures; Breast Neoplasms; Breech Presentation; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Cough; Fractures, Bone; Genital Neoplasms, Female; Hallux Valgus; Hemorrhoids; Hernia, Inguinal; Ileus; Liver Diseases; Migraine Disorders; Neoplasms; Osteoarthritis; Pancreatic Neoplasms; Pancreatitis, Chronic; Peritoneal Neoplasms; Postoperative Complications; Postoperative Nausea and Vomiting; Radiculopathy; Toothache; Urethral Stricture; Wounds and Injuries; Hernia; Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Melanoma; Fractures, Bone; Arrhythmias, Cardiac; Bacteremia; Cellulitis; Gram-Positive Bacterial Infections; Infections; Laryngeal Neoplasms; Osteomyelitis; Prostatic Neoplasms, Castration-Resistant; Skin Diseases; Staphylococcal Infections; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Prostatic Neoplasms, Castration-Resistant; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M3 agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cataract; Miosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION; ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Melanoma; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Central Nervous System Neoplasms; Lymphoma, AIDS-Related; Multiple Myeloma; Rectal Neoplasms; Vulvar Neoplasms; Carcinoma, Embryonal; Choriocarcinoma; Endodermal Sinus Tumor; HIV Infections; Head and Neck Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Pericardial Effusion; Sarcoma, Kaposi; Sex Cord-Gonadal Stromal Tumors; Teratoma; Testicular Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hodgkin Disease; Lymphoma; Pleural Effusion, Malignant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: BUCCAL; ORAL; SUBLINGUAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Menopause; Breast Neoplasms; Hypogonadism; Orchitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colorectal Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-2 adrenergic receptor agonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Substance-Related Disorders; Asthma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Astrocytoma; Brain Neoplasms; Glioblastoma; Granulomatosis with Polyangiitis; Kidney Diseases; Leukemia, Biphenotypic, Acute; Neoplasms; Pulmonary Disease, Chronic Obstructive; Cystic Fibrosis; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Eczema; Lymphoma, AIDS-Related; Abscess; Bacteremia; HIV Infections; Idiopathic Pulmonary Fibrosis; Malaria; Measles; Pneumonia; Pyelonephritis; Sepsis; Staphylococcal Infections; Toxoplasmosis, Ocular; Tuberculosis; Bacterial Infections; Infections; Pneumonia, Pneumocystis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Tuberculosis, Multidrug-Resistant; Tuberculosis; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lymphoma; Pancreatitis; Leukemia; Multiple Myeloma; Acne Vulgaris; Eye Diseases; Hemorrhoids; Nasal Obstruction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Enuresis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC; ORAL; OTIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acanthamoeba Keratitis; Multiple Sclerosis, Relapsing-Remitting; Anemia; Asthma; Conjunctivitis, Allergic; Corneal Injuries; Idiopathic Pulmonary Fibrosis; Inflammation; Leukemia; Multiple Sclerosis; Nephrotic Syndrome; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Rhinitis, Allergic; Uremia; Uveitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter releasing agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Obesity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Monoamine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Narcolepsy; Obesity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Heart Diseases; Substance-Related Disorders; Brain Injuries; Status Epilepticus; Sleep Initiation and Maintenance Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Potassium channel, inwardly rectifying, subfamily J, member 11 opener
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Depressive Disorder; Diabetes Mellitus, Type 2; Obesity; Adenoma, Islet Cell; Hyperinsulinism; Hypertension; Hypoglycemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Keratitis, Herpetic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Coronary Disease; HIV Infections; Inflammation; Ischemia; Anemia; Anemia, Sickle Cell; Diabetes Mellitus, Type 2; Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Liver Neoplasms; Seminoma; Testicular Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia; Astrocytoma; Brain Neoplasms; Glioblastoma; Granulomatosis with Polyangiitis; Kidney Diseases; Leber Congenital Amaurosis; Leukemia, Biphenotypic, Acute; Neoplasms; Pulmonary Disease, Chronic Obstructive; Cystic Fibrosis; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Eczema; Epidermolysis Bullosa; Lymphoma, AIDS-Related; Abscess; Bacteremia; HIV Infections; Idiopathic Pulmonary Fibrosis; Malaria; Measles; Pneumonia; Pyelonephritis; Sepsis; Staphylococcal Infections; Toxoplasmosis, Ocular; Tuberculosis; Bacterial Infections; Infections; Otitis Media; Pneumonia, Pneumocystis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thiazide-sensitive sodium-chloride cotransporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Toxemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Adenoma; Carcinoma, Renal Cell; Colorectal Neoplasms; Hashimoto Disease; Lung Neoplasms; Lymphoma, Follicular; Prostatic Neoplasms, Castration-Resistant
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown