EcoDrugPlus


Trade Names	FLUPHENAZINE FLUPHENAZINE DECANOATE PROLIXIN DECANOATE
Synonyms	Dapotum d Decazate Fluphenazine decanoate Fluphenazini decanoas Lyogen Modecate Modecate conc Moditen depot NSC-169510 Prolixin decanoate QD-10733 SQ-10733
Status
Molecule Category	Free-form
UNII	FMU62K1L3C
EPA CompTox	DTXSID7023069

Datasets:

Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	VIQCGTZFEYDQMR-UHFFFAOYSA-N
Smiles	CCCCCCCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1
InChI	InChI=1S/C32H44F3N3O2S/c1-2-3-4-5-6-7-8-14-31(39)40-24-23-37-21-19-36(20-22-37)17-11-18-38-27-12-9-10-13-29(27)41-30-16-15-26(25-28(30)38)32(33,34)35/h9-10,12-13,15-16,25H,2-8,11,14,17-24H2,1H3

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C32H44F3N3O2S
Molecular Weight	591.78
AlogP	8.0
Hydrogen Bond Acceptor	6.0
Number of Rotational Bond	15.0
Polar Surface Area	36.02
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	41.0

Mechanism of Action	Action	Reference
Dopamine D2 receptor antagonist	ANTAGONIST	PubMed PubMed PubMed Wikipedia

Target Conservation


Protein: Dopamine D2 receptor Description: D(2) dopamine receptor Organism : Homo sapiens P14416 ENSG00000149295

Cross References

Resources	Reference
ChEBI	5124
ChEMBL	CHEMBL1200854
DrugCentral	1213
FDA SRS	FMU62K1L3C
PubChem	3388
SureChEMBL	SCHEMBL41288
ZINC	ZINC000022816725

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

FLUPHENAZINE DECANOATE

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References