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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Irritable Bowel Syndrome; Sleep Wake Disorders; Anxiety; Dementia; Schizophrenia; Urticaria; Depressive Disorder; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Astrocytoma; Glioblastoma; Lymphoma, AIDS-Related; Brain Neoplasms; Central Nervous System Neoplasms; Lymphoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sigma opioid receptor modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alopecia; Brain Neoplasms; Glioblastoma; Leukemia, Plasma Cell; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Blast Crisis; Burkitt Lymphoma; Central Nervous System Neoplasms; Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia-Lymphoma, Adult T-Cell; Lupus Erythematosus, Systemic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Meningitis, Aseptic; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Neuromyelitis Optica; Neutropenia; Opsoclonus-Myoclonus Syndrome; Ovarian Neoplasms; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stiff-Person Syndrome; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Graft vs Host Disease; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Melanoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Sarcoma, Myeloid; Urinary Bladder, Overactive; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Carcinomatosis; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthritis, Rheumatoid; Joint Diseases; Pain; Eye Diseases; Hemorrhoids; Lung Diseases, Obstructive; Nasal Obstruction; Osteoarthritis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Eye Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydropteroate synthase inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY; OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Burns
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Pain; Stomatitis; Alcoholism; Bipolar Disorder; Depression; Depressive Disorder; Dermatitis, Atopic; Sleep Initiation and Maintenance Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glioblastoma; Central Nervous System Neoplasms; Hodgkin Disease; Lymphoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 11A1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Prostatic Neoplasms, Castration-Resistant; Adrenal Cortex Neoplasms; Carcinoma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cognitive Dysfunction; Fatigue; Head and Neck Neoplasms; Heart Arrest; Marijuana Abuse; Mental Disorders; Opioid-Related Disorders; Perceptual Disorders; Respiratory Insufficiency; Schizophrenia; Sepsis; Stroke; Substance-Related Disorders; Tobacco Use Disorder; Borderline Personality Disorder; Brain Injuries; Breast Neoplasms; Bronchial Spasm; Cataract; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Complex Regional Pain Syndromes; Coronavirus Infections; Depressive Disorder, Treatment-Resistant; Epilepsy; Fractures, Multiple; Heart Septal Defects, Ventricular; Hypertrophy; Ischemic Stroke; Lung Neoplasms; Obsessive-Compulsive Disorder; Paget Disease, Extramammary; Respiratory Distress Syndrome; Rett Syndrome; Severe Acute Respiratory Syndrome; Strabismus; Stress Disorders, Post-Traumatic; Subarachnoid Hemorrhage; Temporomandibular Joint Disorders; Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Chronic Pain; Delirium; Depression, Postpartum; Depressive Disorder; Depressive Disorder, Major; Fractures, Bone; Headache; Mucositis; Neoplasms; Neuralgia; Obesity, Morbid; Pain; Pharyngitis; Postoperative Complications; Renal Colic; Rib Fractures; Shock, Septic; Status Asthmaticus; Status Epilepticus; Suicidal Ideation; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D3 receptor agonist
ROUTE OF ADMINISTRATION: INHALATION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Asthma; Hypotension, Orthostatic; Tobacco Use Disorder; Tourette Syndrome; Albinism; Albinism, Oculocutaneous; Angelman Syndrome; Aphasia; Back Pain; Child Development Disorders, Pervasive; Chronic Pain; Cocaine-Related Disorders; Macular Degeneration; Pain; Retinitis Pigmentosa; Schizophrenia; Spinal Cord Injuries; Stress Disorders, Post-Traumatic; Amblyopia; Restless Legs Syndrome; Stroke; Parkinson Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sarcoma, Ewing; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: D2-like dopamine receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Pain; Postoperative Nausea and Vomiting; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dermatitis, Atopic; Epidermolysis Bullosa Dystrophica; Muscular Dystrophy, Duchenne; Pneumonia, Ventilator-Associated; Chorioamnionitis; Cystic Fibrosis; Diabetic Foot; Folliculitis; Leishmaniasis; Leishmaniasis, Cutaneous; Meniere Disease; Neoplasms; Plague; Breast Neoplasms; Cat-Scratch Disease; Colonic Neoplasms; Eczema; Infections; Pain; Rectal Neoplasms; Sepsis; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Phosphodiesterase 4 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Dysuria; Prostatitis; Urethritis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cell membrane inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sepsis; Periapical Periodontitis; Prediabetic State; Severe Acute Respiratory Syndrome; Breast Neoplasms; Candidiasis, Vulvovaginal; Chorioretinitis; Kidney Calculi; Malaria; Nasal Obstruction; Pain; Pneumonia, Pneumocystis; Skin Diseases; Staphylococcal Infections; Vaginosis, Bacterial; Acne Vulgaris; Bacterial Infections; Endometritis; Infections; Intraabdominal Infections; Osteomyelitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Copper chelating agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Central Nervous System Neoplasms; Arthritis, Rheumatoid; Cystinuria; Hepatolenticular Degeneration; Inflammation; Rheumatic Diseases; Spondylitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Polyuria; Urinary Incontinence
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Acne Vulgaris; Enterocolitis, Pseudomembranous; Infections; Osteomyelitis; Pneumonia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Thymidylate synthase inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colonic Neoplasms; Fallopian Tube Neoplasms; Rectal Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Cholangiocarcinoma; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Liver Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; INTRATHECAL; OPHTHALMIC; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Epidermolysis Bullosa; Epidermolysis Bullosa Dystrophica; Epidermolysis Bullosa, Junctional; Abdominal Abscess; Hypotrichosis; Leishmaniasis; Pneumonia, Bacterial; Gonorrhea; Pneumonia; Bacterial Infections; Blepharitis; Conjunctivitis; Corneal Ulcer; Dermatitis; Infections; Inflammation; Keratitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Sleep Initiation and Maintenance Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glutamate [NMDA] receptor negative allosteric modulator
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anorexia Nervosa; Cognitive Dysfunction; Aggression; Bipolar Disorder; Cocaine-Related Disorders; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Epilepsy; Pruritus; Psychomotor Agitation; Subarachnoid Hemorrhage; Suicidal Ideation; Tinnitus; Depressive Disorder, Major; Fractures, Bone; Neoplasms; Opioid-Related Disorders; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glycogen synthase kinase-3 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Brain Concussion; Central Nervous System Neoplasms; Corticobasal Degeneration; Multiple Sclerosis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Supranuclear Palsy, Progressive; Adenomatous Polyposis Coli; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain Neoplasms; Carcinoma, Medullary; Fractures, Bone; Frontotemporal Dementia; Huntington Disease; Machado-Joseph Disease; Multiple System Atrophy; Neuroendocrine Tumors; Spinal Cord Injuries; Spinocerebellar Ataxias; Thyroid Neoplasms; Aggression; Alcoholism; Anxiety; Carotid Stenosis; Child Development Disorders, Pervasive; Conduct Disorder; Dementia; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Neutropenia; Schizophrenia; Stroke; Bipolar Disorder; Depressive Disorder; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sleep Initiation and Maintenance Disorders; Anxiety; Dementia; Depressive Disorder; Schizophrenia