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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Dermatitis, Atopic; HIV Infections; Malaria; Neoplasms; Psoriasis; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Heart Diseases; Hypotension, Orthostatic; Obesity; Prader-Willi Syndrome; Premature Birth; Tachycardia, Ventricular; Ventricular Fibrillation; beta-Thalassemia; Atherosclerosis; Atrial Fibrillation; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 2; Heart Failure; Hypercholesterolemia; Hypertension; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; ST Elevation Myocardial Infarction; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Voltage-gated calcium channel blocker
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine D2 receptor antagonist
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Heart Diseases; Opioid-Related Disorders; Subarachnoid Hemorrhage; Hernia, Inguinal; Respiratory Insufficiency; Severe Acute Respiratory Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Asthma; Smoking Cessation; Hemangioma; Angina Pectoris; Cardiovascular Diseases; Hypertension; Myocardial Infarction; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydropteroate synthase 1 inhibitor
ROUTE OF ADMINISTRATION: ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Non-Small-Cell Lung; Pemphigoid, Benign Mucous Membrane; Pemphigus; Pulmonary Fibrosis; Rosacea; Sarcoidosis; Stroke; Fever; HIV Infections; Malaria; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Severe Acute Respiratory Syndrome; Acne Vulgaris; Dermatitis Herpetiformis; Leprosy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypotension, Orthostatic; Orthostatic Intolerance; Gastrointestinal Hemorrhage; Hyperemesis Gravidarum; Hypoglycemia; Intestinal Obstruction; Myelodysplastic Syndromes; Pain; Wounds and Injuries; Gastroenteritis; Gastroparesis; Gastroschisis; HIV Infections; Headache; Migraine Disorders; Nausea; Neoplasms; Sepsis; Vomiting; Digestive System Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Anemia, Refractory; Leukemia, Myeloid; Myelodysplastic Syndromes; Hepatitis B, Chronic; Leukemia; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Sarcoma, Kaposi; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sulfonylurea receptor 2, Kir6.2 opener
ROUTE OF ADMINISTRATION: ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: DERMATOLOGY; OTHER
THERAPEUTIC INDICATION: Ovarian Neoplasms; Alopecia; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Eye Manifestations; Nasal Obstruction
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Dementia; Schizophrenia; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Obesity; Premenstrual Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tyrosine 3-hydroxylase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psychotic Disorders; Sarcoma, Ewing; Hypertension; Pheochromocytoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-1 antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Sprains and Strains; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: EYE; OTHER
THERAPEUTIC INDICATION: Rectal Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Esophageal Neoplasms; Colorectal Neoplasms; Eye Infections; Herpes Simplex; Keratoconjunctivitis; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Vitamin D receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acute Kidney Injury; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Vitamin D Deficiency; Myocardial Infarction; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Arthralgia; Myalgia; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Ischemic Stroke; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Brain Neoplasms; Glioblastoma; Anxiety; Dementia; Schizophrenia; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dopamine receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 11A1 inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Angiotensin-converting enzyme inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Beta-1 adrenergic receptor antagonist
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Stress Disorders, Post-Traumatic; Atrial Fibrillation; Cerebrovascular Disorders; Essential Hypertension; Heart Diseases; Heart Failure; Hemangioma; Hypertrophy, Left Ventricular; Marfan Syndrome; Mitral Valve Stenosis; Myocardial Ischemia; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Leukemia; Myopia; Neoplasm Metastasis; Renal Insufficiency, Chronic; Urethral Stricture; Appendiceal Neoplasms; Biliary Tract Neoplasms; Carcinoma, Squamous Cell; Cholangiocarcinoma; Cholangitis, Sclerosing; Corneal Opacity; Esophageal Stenosis; Glaucoma, Neovascular; Glaucoma, Open-Angle; Keratoconus; Liver Neoplasms; Pterygium; Sarcoma; Anus Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma in Situ; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Glaucoma; Neoplasms