ETHAMBUTOL HYDROCHLORIDE

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Search structure


Trade Names	ETHAMBUTOL HYDROCHLORIDE MYAMBUTOL
Synonyms	CL 40881 CL-40881 Dadibutol Dexambutol Ebutol Etapiam Ethambutol dihydrochloride Ethambutol hcl Ethambutol hydrochloride Ethambutoli hydrochloridum Etibi Myambutol Mycobutol Mynah 200 Mynah 250
Status
Molecule Category	Salt-form
UNII	QE4VW5FO07
EPA CompTox	DTXSID4045345
Parent Compound:	ETHAMBUTOL

Structure


InChI Key	AUAHHJJRFHRVPV-BZDVOYDHSA-N
Smiles	CC[C@@H](CO)NCCN[C@@H](CC)CO.Cl.Cl
InChI	InChI=1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C10H26Cl2N2O2
Molecular Weight	277.24
AlogP	-0.29
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	9.0
Polar Surface Area	64.52
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	14.0

Pharmacology

Mechanism of Action	Action	Reference
Arabinosyltransferase A inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed PubMed PubMed Wikipedia

Cross References

Resources	Reference
ChEBI	4878
ChEMBL	CHEMBL3140361
FDA SRS	QE4VW5FO07
PubChem	14051
SureChEMBL	SCHEMBL650049

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025