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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glutathione precursor
ROUTE OF ADMINISTRATION: INHALATION; INTRAVENOUS; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Aging; Altitude Sickness; Breast Neoplasms; Cardiomyopathy, Hypertrophic; Fibromyalgia; Gambling; Hearing Loss, Noise-Induced; Irritable Bowel Syndrome; Lymphoma; Mitochondrial Diseases; Neuromuscular Diseases; Niemann-Pick Disease, Type C; Polycythemia Vera; Primary Myelofibrosis; Pseudomyxoma Peritonei; Renal Insufficiency; Respiratory Tract Infections; Substance-Related Disorders; Thrombocythemia, Essential; beta-Thalassemia; Acute Lung Injury; Adrenoleukodystrophy; Alcohol Drinking; Alcoholism; Amphetamine-Related Disorders; Arrhythmias, Cardiac; Asperger Syndrome; Autistic Disorder; Bacteremia; Biliary Atresia; Bipolar Disorder; Brain Injuries; Bronchitis, Chronic; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Cognitive Dysfunction; De Lange Syndrome; Dry Eye Syndromes; Epilepsy; Fuchs' Endothelial Dystrophy; Gaucher Disease; Hearing Loss; Hepatic Veno-Occlusive Disease; Homocystinuria; Ischemic Stroke; Kidney Diseases; Lupus Erythematosus, Systemic; Melanoma; Mental Disorders; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Diseases; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Pain; Parkinson Disease; Polycystic Ovary Syndrome; Premature Birth; Purpura, Thrombocytopenic, Idiopathic; Pyelonephritis; Retinitis Pigmentosa; Rhabdomyolysis; ST Elevation Myocardial Infarction; Scleroderma, Diffuse; Stress Disorders, Post-Traumatic; Stroke; Thrombocytopenia; Tobacco Use Disorder; Tourette Syndrome; Transposition of Great Vessels; Trichotillomania; Tuberculosis; Acute Kidney Injury; Anemia, Sickle Cell; Atrial Fibrillation; Bulimia Nervosa; Common Cold; Coronary Disease; Diabetic Foot; Graft vs Host Disease; Hematologic Diseases; Hepatitis, Alcoholic; Idiopathic Pulmonary Fibrosis; Infertility; Infertility, Female; Liver Failure, Acute; Marijuana Abuse; Mucositis; Myocardial Infarction; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Renal Insufficiency, Chronic; Reperfusion Injury; Respiratory Tract Diseases; Schizophrenia; Severe Acute Respiratory Syndrome; Sinusitis; Chemical and Drug Induced Liver Injury; Cystic Fibrosis; Eye Diseases; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Leukemia; Eye Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Alanine racemase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anxiety; Sleep Apnea Syndromes; Agoraphobia; Alcohol Drinking; Bipolar Disorder; Brain Injuries; Cocaine-Related Disorders; Depressive Disorder, Major; Fibromyalgia; Low Back Pain; Opioid-Related Disorders; Psychotic Disorders; Stroke; Substance-Related Disorders; Tobacco Use Disorder; Asperger Syndrome; Autistic Disorder; Obsessive-Compulsive Disorder; Pain; Panic Disorder; Phobia, Social; Phobic Disorders; Schizophrenia; Smoking Cessation; Stress Disorders, Post-Traumatic; Tuberculosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Fanconi Anemia; Malnutrition; Burns; Klinefelter Syndrome; Rotator Cuff Injuries; Neoplasms; Pressure Ulcer; Turner Syndrome
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Acetylcholinesterase activator
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Myasthenia Gravis; Poisoning
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Enterocolitis, Pseudomembranous; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Metabolites
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Depressive Disorder, Major; Irritable Bowel Syndrome; Psoriasis; Temporomandibular Joint Disorders; Tobacco Use Disorder; Anxiety; Dementia; Dyspepsia; Gastroesophageal Reflux; Gastroparesis; Schizophrenia; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections; Multiple Sclerosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sulfonylurea receptor 1, Kir6.2 blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Cataract; Diabetes Mellitus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Poisoning; Organophosphate Poisoning
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Plasminogen inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Craniosynostoses; Inflammation; Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia; Blast Crisis; Central Nervous System Neoplasms; Chordoma; Crohn Disease; Fallopian Tube Neoplasms; Neoplasms, Germ Cell and Embryonal; Oligodendroglioma; Peritoneal Neoplasms; beta-Thalassemia; Adenoma, Islet Cell; Anemia, Aplastic; Anemia, Diamond-Blackfan; Brain Neoplasms; Breast Neoplasms, Male; Bronchiectasis; Burkitt Lymphoma; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Ganglioneuroblastoma; Graft vs Host Disease; Granuloma, Lethal Midline; Hematologic Diseases; Hematologic Neoplasms; Histiocytosis; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immunoblastic Lymphadenopathy; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Erythroblastic, Acute; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Mycosis Fungoides; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Plasmacytoma; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Stiff-Person Syndrome; Testicular Neoplasms; Thalassemia; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Amyloidosis, Familial; Anemia, Sickle Cell; Breast Neoplasms; Colorectal Neoplasms; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Ovarian Neoplasms; Retinoblastoma; Sarcoma; Sarcoma, Ewing; Smoldering Multiple Myeloma; Carcinoma; Multiple Myeloma; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA gyrase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Depressive Disorder; Back Pain; Small Cell Lung Carcinoma; Depression
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: FOR RX COMPOUNDING; OPHTHALMIC; ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Erectile Dysfunction; Hepatitis C; Leukemia, Lymphocytic, Chronic, B-Cell; Renal Insufficiency; Bulimia Nervosa; Colorectal Neoplasms; Gastroparesis; Pulmonary Disease, Chronic Obstructive; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Chlamydia Infections; Epidermolysis Bullosa; Gastrointestinal Hemorrhage; HIV Infections; Hematemesis; Pneumonia; Acne Vulgaris; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Peptidoglycan inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Child Development Disorders, Pervasive; Melanoma; Osteoarthritis; Peritonitis; Renal Insufficiency; Sinusitis; Carcinoma, Hepatocellular; Colitis, Ulcerative; Constipation; Crohn Disease; Cystic Fibrosis; Graft vs Host Disease; Hematologic Neoplasms; Joint Diseases; Neonatal Sepsis; Obesity; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Prediabetic State; Renal Insufficiency, Chronic; Abscess; Bacteremia; Cellulitis; Cholangitis, Sclerosing; Clostridium Infections; Conjunctivitis, Bacterial; Cross Infection; Diabetic Foot; Gram-Positive Bacterial Infections; Infections; Inflammation; Osteomyelitis; Pneumonia; Pneumonia, Bacterial; Staphylococcal Infections; Staphylococcal Skin Infections; Bacterial Infections; Diarrhea; Endocarditis; Enterocolitis; Eye Infections; Respiratory Tract Infections; Sepsis; Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Amiloride-sensitive sodium channel, ENaC blocker
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Hypercholesterolemia; Cardiovascular Diseases; Edema; Heart Failure; Hyperaldosteronism; Hypertension; Liver Cirrhosis; Nephrotic Syndrome; Toxemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Erectile Dysfunction; Neoplasms; Cocaine-Related Disorders; Rett Syndrome; Sciatica; Sleep Apnea, Obstructive; Alcoholism; Depressive Disorder, Major; Gastroesophageal Reflux; Stress Disorders, Post-Traumatic; Depressive Disorder
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Ergosterol sequestering agent
ROUTE OF ADMINISTRATION: INJECTION; ORAL; TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Leishmaniasis, Cutaneous; Aspergillosis, Allergic Bronchopulmonary; Candidiasis, Chronic Mucocutaneous; Candidiasis, Invasive; Fuchs' Endothelial Dystrophy; Intracranial Hypertension; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Blastomycosis; Candidiasis, Vulvovaginal; Leishmaniasis; Leishmaniasis, Mucocutaneous; Leukemia; Lung Diseases; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasms; Vaginosis, Bacterial; Aspergillosis; Candidiasis; Cryptococcosis; Histoplasmosis; Infections; Leishmaniasis, Visceral; Meningitis, Cryptococcal; Mucormycosis; Mycoses; Sporotrichosis; Zygomycosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Ergosterol sequestering agent
ROUTE OF ADMINISTRATION: ORAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Dental Caries; Kidney Diseases; Bacteremia; Burns; Graft vs Host Disease; Pneumonia; Stomatitis, Denture; Candidiasis, Oral; HIV Infections; Leukemia; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Stomatitis; Tobacco Use Disorder; Vaginosis, Bacterial; Candidiasis; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Acne Vulgaris; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Peptidoglycan inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Clostridium Infections; Cystic Fibrosis; Abscess; Bacterial Infections; Cellulitis; Cross Infection; Skin Diseases; Staphylococcal Skin Infections; Endocarditis; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Norepinephrine transporter inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Carcinoma, Small Cell; Dermatitis, Atopic; Psoriasis; Gastroparesis; Depression
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium channel alpha subunit blocker
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INHALATION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Pain
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Pancreatic Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tubulin inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Fibromatosis, Aggressive; Kidney Neoplasms; Melanoma; Mesothelioma; Sarcoma; Urethral Neoplasms; Lung Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Testicular Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Communicable Diseases; Hodgkin Disease; Lymphoma; Lymphoma, Large B-Cell, Diffuse