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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: ORAL; TOPICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Sickle Cell; Kidney Diseases; Folliculitis; Candidiasis, Oral; Candidiasis, Vulvovaginal; HIV Infections; Vaginal Discharge; Vaginosis, Bacterial; Candidiasis; Infections; Mycoses; Pruritus; Skin Diseases, Infectious; Tinea; Tinea Pedis; Tinea cruris
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INHALATION; OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Bronchopulmonary Dysplasia; Dry Eye Syndromes; Renal Insufficiency, Chronic; Sinusitis; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive allosteric modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
THERAPEUTIC INDICATION: Neuralgia; Marijuana Abuse; REM Sleep Behavior Disorder; Anxiety; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Epilepsy, Tonic-Clonic; Pain; Schizophrenia; Status Epilepticus; Epilepsy; Panic Disorder; Seizures
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Dihydropteroate synthetase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Estrogen receptor alpha agonist
ROUTE OF ADMINISTRATION: ORAL; TOPICAL; TRANSDERMAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; HIV Infections; Osteoporosis; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Urinary Tract Infections; Amenorrhea; Anorexia Nervosa; Atrophic Vaginitis; Atrophy; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Endometriosis; Hot Flashes; Infertility; Leiomyoma; Menopause; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Dyspareunia; Hypogonadism; Primary Ovarian Insufficiency
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M2 antagonist
ROUTE OF ADMINISTRATION: TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER; UROLOGY AND KIDNEY
THERAPEUTIC INDICATION: Paget Disease, Extramammary; Rhinitis, Allergic, Seasonal; Sleep Apnea Syndromes; Sleep Apnea, Obstructive; Enuresis; Hyperhidrosis; Polyneuropathies; Urinary Bladder, Neurogenic; Polyuria; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Urge
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hemorrhoids; Pruritus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Radioactive metals chelating agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Androgen Receptor agonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia, Aplastic; Dyskeratosis Congenita; Fanconi Anemia; Endometrial Neoplasms; Mastodynia; Myelodysplastic Syndromes; Purpura, Thrombocytopenic, Idiopathic; Purpura, Thrombotic Thrombocytopenic; Infertility; Endometriosis; Fibrocystic Breast Disease
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bone Neoplasms; Breast Neoplasms; Glioma; Kidney Neoplasms; Neoplasm Metastasis; Sarcoma; Lung Neoplasms; Lymphoma; Lymphoma, AIDS-Related; Melanoma; Astrocytoma; Central Nervous System Neoplasms; Glioblastoma; Gliosarcoma; Leukemia, Myeloid, Acute; Medulloblastoma; Multiple Myeloma; Brain Neoplasms; Hodgkin Disease; Neoplasms
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor; anion channel positive modulator
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Colonic bacteria substrate
ROUTE OF ADMINISTRATION: ORAL; RECTAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Premature Birth; Dermatitis, Atopic; Liver Cirrhosis; Brain Diseases; Constipation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Intestinal Obstruction; Breast Neoplasms; Clostridium Infections; Eczema; Neoplasms; Paget Disease, Extramammary; Carcinoma, Non-Small-Cell Lung; Diarrhea; Fecal Incontinence
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Acanthamoeba Keratitis; Diabetic Foot; Neonatal Sepsis; Peri-Implantitis; Periodontal Diseases; Pneumonia, Ventilator-Associated; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Stomatitis; Bacteremia; Bacterial Infections; Communicable Diseases; Dental Caries; Gingivitis; Neutropenia; Periodontitis; Pharyngitis; Pneumonia; Staphylococcal Infections; Eye Infections; Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Sepsis; Infections; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Arthralgia; Myalgia; Rheumatic Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Progesterone receptor agonist
ROUTE OF ADMINISTRATION: INJECTION; INTRAUTERINE; ORAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Anorexia Nervosa; Bulimia Nervosa; Cervical Intraepithelial Neoplasia; Cocaine-Related Disorders; Coronary Disease; Depression, Postpartum; Endometrial Neoplasms; HIV Infections; Marijuana Abuse; Orthostatic Intolerance; Placenta Previa; Polycystic Ovary Syndrome; Pre-Eclampsia; Severe Acute Respiratory Syndrome; Tobacco Use Disorder; Vulvar Lichen Sclerosus; Alzheimer Disease; Angina, Unstable; Bone Diseases, Metabolic; Brain Injuries; Breast Neoplasms; Diabetes Mellitus; Epilepsy; Hypercholesterolemia; Hypertension; Infertility; Infertility, Female; Leiomyoma; Memory Disorders; Menopause; Myocardial Ischemia; Osteoporosis; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pregnancy; Premature Birth; Thrombosis; Amenorrhea; Endometrial Hyperplasia; Uterine Hemorrhage
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Human herpesvirus 1 DNA polymerase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Herpes Simplex; Eye Infections; Virus Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor agonist
ROUTE OF ADMINISTRATION: INHALATION; INJECTION; INTRAMUSCULAR; INTRAOCULAR; INTRAVENOUS; SUBCUTANEOUS
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anaphylaxis; Chronic Pain; Infections; Tachypnea; Acute Lung Injury; Appendicitis; Breast Neoplasms; Cognitive Dysfunction; Death, Sudden, Cardiac; Hemoptysis; Hypospadias; Hypotension; Musculoskeletal Diseases; Osteoarthritis, Knee; Rotator Cuff Injuries; Shock; Tachycardia, Ventricular; Ventricular Fibrillation; Wounds and Injuries; Bronchiolitis; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Hemorrhage; Genital Neoplasms, Male; Heart Failure; Myoma; Osteoarthritis; Pain; Pulpitis; Rhinitis, Allergic, Perennial; Stomach Neoplasms; Angioedema; Asthma; Bronchial Spasm; Cardiovascular Diseases; Glaucoma; Heart Arrest; Hemorrhage; Hypersensitivity; Lung Diseases, Obstructive; Muscle Cramp; Mydriasis; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Serum Sickness; Shock, Septic; Sinusitis; Urticaria
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Anxiety; Substance Withdrawal Syndrome; Urinary Bladder, Neurogenic; Amphetamine-Related Disorders; Severe Acute Respiratory Syndrome; Tobacco Use Disorder; Alcoholism; Kidney Calculi; Stress Disorders, Post-Traumatic; Hypertension
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Breast Neoplasms; Neoplasms; Hyperemia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Colorectal Neoplasms, Hereditary Nonpolyposis; Distal Myopathies; Alzheimer Disease; Breast Neoplasms; Duodenal Ulcer; Neuralgia; Pleural Effusion; Prostatic Neoplasms; Wounds and Injuries; Low Back Pain; Migraine Disorders; Multiple Sclerosis; Osteoarthritis, Hip; Osteoarthritis, Knee; Peptic Ulcer; Severe Acute Respiratory Syndrome; Acute Pain; Arthralgia; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Rheumatoid; Back Pain; Bursitis; Common Cold; Dysmenorrhea; Fever; Gout; Headache; Muscle Cramp; Myalgia; Osteoarthritis; Pain; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stomach Ulcer; Tendinopathy; Toothache; Vaginitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Prostaglandin E2 receptor agonist
ROUTE OF ADMINISTRATION: ENDOCERVICAL; VAGINAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Abortion, Incomplete; Pain; Pregnancy
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Psoriasis; Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Optic Neuritis; Urticaria; Angioedema; Dermatitis; Hypersensitivity; Pruritus