PRALIDOXIME CHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII 38X7XS076H
EPA CompTox DTXSID1023495
Parent Compound: PRALIDOXIME

Structure

InChI Key HIGSLXSBYYMVKI-UHFFFAOYSA-N
Smiles C[n+]1ccccc1/C=N/O.[Cl-]
InChI
InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C7H9ClN2O
Molecular Weight 172.61
AlogP 0.32
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 1.0
Polar Surface Area 36.47
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 10.0

Pharmacology

Mechanism of Action Action Reference
Acetylcholinesterase activator ACTIVATOR KEGG DailyMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - - 4-38
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Rattus norvegicus
- - - - 4-38

Target Conservation

Protein: Acetylcholinesterase
Description: Acetylcholinesterase
Organism : Homo sapiens
P22303 ENSG00000087085

Cross References

Resources Reference
ChEBI 8355
ChEMBL CHEMBL748
FDA SRS 38X7XS076H
PubChem 135445761
SureChEMBL SCHEMBL61419
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