ERYTHROMYCIN STEARATE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII LXW024X05M
EPA CompTox DTXSID0020571
Parent Compound: ERYTHROMYCIN

Structure

InChI Key YAVZHCFFUATPRK-YZPBMOCRSA-N
Smiles CCCCCCCCCCCCCCCCCC(=O)O.CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
InChI
InChI=1S/C37H67NO13.C18H36O2/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2-17H2,1H3,(H,19,20)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C55H103NO15
Molecular Weight 1018.42
AlogP 1.79
Hydrogen Bond Acceptor 14.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 7.0
Polar Surface Area 193.91
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 51.0

Metabolites Network

visNetwork

Pharmacology

Mechanism of Action Action Reference
Bacterial 70S ribosome inhibitor INHIBITOR PubMed FDA
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 99.85-103.84
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cricetulus griseus
- - - - 99.85-103.84

Cross References

Resources Reference
ChEBI 34742
ChEMBL CHEMBL1200510
FDA SRS LXW024X05M
PubChem 12559
SureChEMBL SCHEMBL536998
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