EcoDrugPlus


Trade Names	MAXIBOLIN
Synonyms	Durabolin-o Duraboral Ethylestrenol Ethylnandrol Ethyloestrenol Maxibolin NSC-37726 Orabolin
Status
Molecule Category	Free-form
ATC	A14AB02
UNII	ADC79EK5Q8
EPA CompTox	DTXSID6023024

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Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

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SubStructure

Threshold (%) >= 70


InChI Key	AOXRBFRFYPMWLR-XGXHKTLJSA-N
Smiles	CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3CC[C@@]21C
InChI	InChI=1S/C20H32O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h6,15-18,21H,3-5,7-13H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C20H32O
Molecular Weight	288.48
AlogP	5.09
Hydrogen Bond Acceptor	1.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	1.0
Polar Surface Area	20.23
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	21.0

Mechanism of Action	Action	Reference
Androgen Receptor agonist	AGONIST	ISBN PubMed

Target Conservation


Protein: Androgen Receptor Description: Androgen receptor Organism : Homo sapiens P10275 ENSG00000169083

Cross References

Resources	Reference
ChEBI	31578
ChEMBL	CHEMBL1200623
DrugBank	DB01493
DrugCentral	1094
FDA SRS	ADC79EK5Q8
Guide to Pharmacology	6948
PubChem	13765
SureChEMBL	SCHEMBL147908
ZINC	ZINC000004215863

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

ETHYLESTRENOL

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References