NORTRIPTYLINE HYDROCHLORIDE

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Trade Names
Synonyms
Status
Molecule Category Salt-form
UNII 00FN6IH15D
EPA CompTox DTXSID2045109
Parent Compound: NORTRIPTYLINE

Structure

InChI Key SHAYBENGXDALFF-UHFFFAOYSA-N
Smiles CNCCC=C1c2ccccc2CCc2ccccc21.Cl
InChI
InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H22ClN
Molecular Weight 299.85
AlogP 3.83
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 12.03
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 20.0

Pharmacology

Mechanism of Action Action Reference
Norepinephrine transporter inhibitor INHIBITOR Wikipedia FDA

Target Conservation

Protein: Norepinephrine transporter
Description: Sodium-dependent noradrenaline transporter
Organism : Homo sapiens
P23975 ENSG00000103546
Protein: Serotonin transporter
Description: Sodium-dependent serotonin transporter
Organism : Homo sapiens
P31645 ENSG00000108576

Cross References

Resources Reference
ChEBI 7641
ChEMBL CHEMBL1201156
FDA SRS 00FN6IH15D
Guide to Pharmacology 2404
KEGG C07274
PubChem 13468
SureChEMBL SCHEMBL41329
ZINC ZINC01530741
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