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MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bile acids sequestering agent
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Coronary Disease; HIV Infections; Inflammation; Ischemia; Anemia; Anemia, Sickle Cell; Diabetes Mellitus, Type 2; Glaucoma
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Histamine H1 receptor antagonist
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Rhinitis, Allergic, Seasonal
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial dihydrofolate reductase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Anemia; Astrocytoma; Brain Neoplasms; Glioblastoma; Granulomatosis with Polyangiitis; Kidney Diseases; Leber Congenital Amaurosis; Leukemia, Biphenotypic, Acute; Neoplasms; Pulmonary Disease, Chronic Obstructive; Cystic Fibrosis; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Eczema; Epidermolysis Bullosa; Lymphoma, AIDS-Related; Abscess; Bacteremia; HIV Infections; Idiopathic Pulmonary Fibrosis; Malaria; Measles; Pneumonia; Pyelonephritis; Sepsis; Staphylococcal Infections; Toxoplasmosis, Ocular; Tuberculosis; Bacterial Infections; Infections; Otitis Media; Pneumonia, Pneumocystis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Tuberculosis, Multidrug-Resistant; Tuberculosis; Bacterial Infections; Eye Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cytochrome P450 51 inhibitor
ROUTE OF ADMINISTRATION: BUCCAL; INJECTION
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; PREGNANCY AND GYNECOLOGY
THERAPEUTIC INDICATION: Stomatitis; HIV Infections; Infections; Mycoses; Pruritus; Tinea; Tinea Pedis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Gram-Positive Bacterial Infections; Mastitis; Enterobacteriaceae Infections; Staphylococcal Infections; Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 1; Neuralgia; Purpura, Thrombocytopenic, Idiopathic; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Refractive Errors; Miosis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Cyclooxygenase inhibitor
ROUTE OF ADMINISTRATION: INTRAVENOUS; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Alzheimer Disease; Hypotension, Orthostatic; Malaria; Muscular Dystrophy, Duchenne; Osteoarthritis, Knee; Premature Birth; Rhinitis, Allergic, Seasonal; Temporomandibular Joint Disorders; Brachial Plexus Neuritis; Bronchopulmonary Dysplasia; Cognitive Dysfunction; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Emphysema; Enuresis; Epilepsies, Partial; Glioma; Granulomatous Disease, Chronic; Hemorrhage; Hypertension; Muscular Diseases; Pancreatitis; Periodontitis; Pre-Eclampsia; Retinopathy of Prematurity; Sinusitis; Spondylarthropathies; Spondylosis; Stomatitis, Aphthous; Sunburn; Tension-Type Headache; Tooth Diseases; Tuberculosis; Wounds and Injuries; Altitude Sickness; Breast Neoplasms; Burns; Causalgia; Cerebral Palsy; Chronic Pain; Fractures, Bone; HIV Infections; Hypospadias; Infections; Low Back Pain; Multiple Sclerosis; Neck Pain; Peptic Ulcer; Pulpitis; Respiratory Distress Syndrome; Shock, Septic; Sleep Apnea, Obstructive; Sprains and Strains; Tibial Fractures; Vasculitis; Acute Pain; Arthralgia; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Back Pain; Cardiovascular Diseases; Common Cold; Ductus Arteriosus, Patent; Dysmenorrhea; Fever; Headache; Influenza, Human; Migraine Disorders; Muscle Cramp; Myalgia; Osteoarthritis; Pain; Pharyngitis; Rheumatic Diseases; Toothache; Vaginitis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Carcinoma, Squamous Cell; Hypertension; Laryngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Prostatic Neoplasms; Angina, Stable
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetic Cardiomyopathies; Heart Failure; Heart Failure, Diastolic; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Glucocorticoid receptor agonist
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Skin Diseases
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bile acids sequestering agent
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Adrenergic receptor alpha-2 agonist
ROUTE OF ADMINISTRATION: ORAL; TRANSDERMAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Brain Ischemia; Cocaine-Related Disorders; Dermatitis, Atopic; Hemorrhage; Heroin Dependence; Hypotension, Orthostatic; Orthostatic Intolerance; Anxiety; Brain Injuries; Breast Neoplasms; Child Development Disorders, Pervasive; Diabetic Neuropathies; Low Back Pain; Marijuana Abuse; Musculoskeletal Diseases; Opioid-Related Disorders; Stomatitis; Substance-Related Disorders; Cardiovascular Diseases; Delirium; Fecal Incontinence; Genital Neoplasms, Male; Hyperemesis Gravidarum; Neonatal Abstinence Syndrome; Pain; Postoperative Complications; Pregnancy; Scoliosis; Stress Disorders, Post-Traumatic; Attention Deficit Disorder with Hyperactivity; Glaucoma; Hypertension; Migraine Disorders; Neoplasms; Neuralgia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Muscarinic acetylcholine receptor M1 agonist
ROUTE OF ADMINISTRATION: OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Urinary Incontinence; Dry Eye Syndromes; Presbyopia; Glaucoma; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Miosis; Ocular Hypertension; Sjogren's Syndrome; Xerostomia
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Tubulin inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Glioma; Hookworm Infections; Pruritus; Anemia; Colorectal Neoplasms; Necatoriasis; Helminthiasis
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Hypersensitivity
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: IMMUNE SYSTEM; OTHER; PEDIATRICS
THERAPEUTIC INDICATION: Astrocytoma; Brain Neoplasms; Central Serous Chorioretinopathy; Glioblastoma; Obesity; Obesity, Morbid; Postoperative Complications; Syphilis, Congenital; Asthma; Bacteremia; Buruli Ulcer; Chlamydia Infections; Colitis, Ulcerative; Head and Neck Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Mastitis; Periapical Periodontitis; Pneumonia, Bacterial; Pseudomyxoma Peritonei; Tuberculosis; Tuberculosis, Pulmonary; Vaginosis, Bacterial; Abscess; Bronchitis, Chronic; Cholecystitis; Communicable Diseases; Dyspepsia; Endocarditis; Enterobacteriaceae Infections; Fever; Gastritis; Helicobacter Infections; Hemorrhage; Hepatitis, Alcoholic; Influenza, Human; Low Back Pain; Lymphoma, Non-Hodgkin; Malaria, Falciparum; Malnutrition; Neutropenia; Otitis Media, Suppurative; Periodontitis; Pyelonephritis; Severe Acute Respiratory Syndrome; Stomach Ulcer; Urinary Bladder Neoplasms; Bacterial Infections; Duodenal Ulcer; Gonorrhea; Infections; Otitis Media; Pharyngitis; Pneumonia; Respiratory Tract Infections; Sinusitis; Soft Tissue Infections; Tonsillitis; Urinary Tract Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Attention Deficit Disorder with Hyperactivity; Psychotic Disorders
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: GABA-A receptor negative allosteric modulator
ROUTE OF ADMINISTRATION: TOPICAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Lice Infestations; Ectoparasitic Infestations
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Acyl coenzyme A:cholesterol acyltransferase 1 inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Diabetes Mellitus, Type 2; Diabetes Mellitus
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Bacterial penicillin-binding protein inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Bacterial Infections
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Unknown
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Multiple Sclerosis; Fever; Tachycardia, Ventricular; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Carnitine O-palmitoyltransferase 1, muscle isoform inhibitor
ROUTE OF ADMINISTRATION: Unknown
STATUS: Approved
THERAPEUTIC AREA: Unknown
THERAPEUTIC INDICATION: Unknown
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DOPA decarboxylase inhibitor
ROUTE OF ADMINISTRATION: ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Amyotrophic Lateral Sclerosis; Angelman Syndrome; Asthma; Hypertension; Hypotension, Orthostatic; Tobacco Use Disorder; Albinism, Oculocutaneous; Aphasia; Attention Deficit Disorder with Hyperactivity; Back Pain; Chronic Pain; Cocaine-Related Disorders; Fibromyalgia; Macular Degeneration; Multiple Sclerosis; Pain; Retinitis Pigmentosa; Schizophrenia; Spinal Cord Injuries; Amblyopia; Dysautonomia, Familial; Stroke; Parkinson Disease; Parkinson Disease, Postencephalitic; Parkinson Disease, Secondary; Wounds and Injuries
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: Sodium/potassium-transporting ATPase inhibitor
ROUTE OF ADMINISTRATION: INJECTION; ORAL
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Angioedemas, Hereditary; Cytomegalovirus Infections; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epilepsy; Essential Hypertension; HIV Infections; Head and Neck Neoplasms; Hepatitis B, Chronic; Hepatitis C; Infections; Inflammation; Influenza, Human; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Nausea; Neoplasms; Pancreatic Neoplasms; Substance-Related Disorders; von Hippel-Lindau Disease; Arthritis, Rheumatoid; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Keratosis, Actinic; Non-alcoholic Fatty Liver Disease; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Tachycardia, Supraventricular; Atrial Fibrillation; Cardiovascular Diseases; Heart Failure
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: 70S ribosome inhibitor
ROUTE OF ADMINISTRATION: INHALATION; OPHTHALMIC
STATUS: Approved
THERAPEUTIC AREA: OTHER; RESPIRATORY
THERAPEUTIC INDICATION: Bronchopulmonary Dysplasia; Dry Eye Syndromes; Renal Insufficiency, Chronic; Sinusitis; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation
MOLECULE TYPE: Small molecule
MECHANISMS OF ACTION: DNA inhibitor
ROUTE OF ADMINISTRATION: INJECTION
STATUS: Approved
THERAPEUTIC AREA: OTHER
THERAPEUTIC INDICATION: Breast Neoplasms; Colonic Neoplasms; Kidney Neoplasms; Lung Neoplasms; Thyroid Neoplasms; Neuroendocrine Tumors; Leiomyosarcoma; Lymphoma; Lymphoma, T-Cell, Peripheral; Neuroblastoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Synovial; Skin Neoplasms; Hodgkin Disease; Melanoma; Neoplasms