EcoDrugPlus


Synonyms	(-)-propoxyphene L-propoxyphene Levopropoxyphene Propoxyphene, (-)- Propoxyphene, l-
Status
Molecule Category	Free-form
UNII	U75VZ9PK1J
EPA CompTox	DTXSID8023212


InChI Key	XLMALTXPSGQGBX-PGRDOPGGSA-N
Smiles	CCC(=O)O[C@@](Cc1ccccc1)(c1ccccc1)[C@@H](C)CN(C)C
InChI	InChI=1S/C22H29NO2/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19/h6-15,18H,5,16-17H2,1-4H3/t18-,22+/m0/s1

Property Name	Value
Molecular Formula	C22H29NO2
Molecular Weight	339.48
AlogP	4.28
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	8.0
Polar Surface Area	29.54
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	25.0

Resources	Reference
ChEBI	51174
ChEMBL	CHEMBL1738990
DrugBank	DB06793
DrugCentral	1573
FDA SRS	U75VZ9PK1J
PubChem	200742
SureChEMBL	SCHEMBL158770
ZINC	ZINC000001530767

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

LEVOPROPOXYPHENE

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