| Trade Names | |
| Synonyms | |
| Status | |
| Molecule Category | Salt-form |
| UNII | M6Q1EO9TD0 |
| EPA CompTox | DTXSID50874031 |
| Parent Compound: | AMANTADINE |
Structure
| InChI Key | WOLHOYHSEKDWQH-UHFFFAOYSA-N |
|---|---|
| Smiles | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C10H18ClN |
| Molecular Weight | 187.71 |
| AlogP | 1.91 |
| Hydrogen Bond Acceptor | 1.0 |
| Hydrogen Bond Donor | 1.0 |
| Polar Surface Area | 26.02 |
| Molecular species | BASE |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 11.0 |
Pharmacology
| Mechanism of Action | Action | Reference |
|---|---|---|
| Glutamate [NMDA] receptor antagonist | ANTAGONIST | DailyMed Wikipedia |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Ion channel
Other ion channel
Miscellaneous ion channel
Type A influenza virus matrix-2 channel family
|
- | - | - | - | 0-35 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 60.52-88.29 |
Cricetulus griseus
Influenza A virus
Target Conservation
|
Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 2D Organism : Homo sapiens O15399 ENSG00000105464 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 3B Organism : Homo sapiens O60391 ENSG00000116032 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 1 Organism : Homo sapiens Q05586 ENSG00000176884 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 2A Organism : Homo sapiens Q12879 ENSG00000183454 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 2B Organism : Homo sapiens Q13224 ENSG00000273079 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 2C Organism : Homo sapiens Q14957 ENSG00000161509 |
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Protein: Glutamate [NMDA] receptor Description: Glutamate receptor ionotropic, NMDA 3A Organism : Homo sapiens Q8TCU5 ENSG00000198785 |
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Cross References
| Resources | Reference |
|---|---|
| ChEBI | 2619 |
| ChEMBL | CHEMBL1569 |
| FDA SRS | M6Q1EO9TD0 |
| Guide to Pharmacology | 4128 |
| KEGG | C07939 |
| PDB | 308 |
| PubChem | 64150 |
| SureChEMBL | SCHEMBL40713 |
| ZINC | ZINC00968256 |
CONTENTS
