EcoDrugPlus


Trade Names	MAFENIDE ACETATE SULFAMYLON
Synonyms	Mafenide acetate Sulfamylon
Status
Molecule Category	Salt-form
UNII	RQ6LP6Z0WY
EPA CompTox	DTXSID00156334

Trade Names

MAFENIDE ACETATE

SULFAMYLON

Synonyms

Mafenide acetate

Sulfamylon

Status

Molecule Category

Salt-form

UNII

RQ6LP6Z0WY

EPA CompTox

DTXSID00156334


InChI Key	UILOTUUZKGTYFQ-UHFFFAOYSA-N
Smiles	CC(=O)O.NCc1ccc(S(N)(=O)=O)cc1
InChI	InChI=1S/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4)

InChI Key

UILOTUUZKGTYFQ-UHFFFAOYSA-N

Smiles

CC(=O)O.NCc1ccc(S(N)(=O)=O)cc1

InChI

InChI=1S/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4)

Property Name	Value
Molecular Formula	C9H14N2O4S
Molecular Weight	246.29
AlogP	-0.21
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	2.0
Polar Surface Area	86.18
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	12.0

Property Name

Value

Molecular Formula

C9H14N2O4S

Molecular Weight

246.29

AlogP

-0.21

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

2.0

Number of Rotational Bond

2.0

Polar Surface Area

86.18

Molecular species

BASE

Aromatic Rings

1.0

Heavy Atoms

12.0

Mechanism of Action	Action	Reference
Bacterial dihydropteroate synthase inhibitor	INHIBITOR	FDA ISBN PubMed

Mechanism of Action

Action

Reference

Bacterial dihydropteroate synthase inhibitor

INHIBITOR

FDA ISBN PubMed

Resources	Reference
ChEBI	31792
ChEMBL	CHEMBL1201161
FDA SRS	RQ6LP6Z0WY
KEGG	C07106
PubChem	25590
SureChEMBL	SCHEMBL41627
ZINC	ZINC00001644

Resources

Reference

ChEBI

ChEMBL

FDA SRS

KEGG

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MAFENIDE ACETATE

Structure

Physicochemical Descriptors

Pharmacology

Cross References