EcoDrugPlus


Synonyms	Dalmane Flurazepam Insumin
Status
Molecule Category	Free-form
ATC	N05CD01
UNII	IHP475989U
EPA CompTox	DTXSID1023071


InChI Key	SAADBVWGJQAEFS-UHFFFAOYSA-N
Smiles	CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21
InChI	InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3

Property Name	Value
Molecular Formula	C21H23ClFN3O
Molecular Weight	387.89
AlogP	4.0
Hydrogen Bond Acceptor	3.0
Number of Rotational Bond	6.0
Polar Surface Area	35.91
Molecular species	BASE
Aromatic Rings	2.0
Heavy Atoms	27.0

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Rattus norvegicus	270	-	-	-	-

Resources	Reference
ChEBI	5128
ChEMBL	CHEMBL968
DrugBank	DB00690
DrugCentral	1218
FDA SRS	IHP475989U
Human Metabolome Database	HMDB0014828
Guide to Pharmacology	7188
PDB	FL7
PharmGKB	PA449681
PubChem	3393
SureChEMBL	SCHEMBL29793
ZINC	ZINC000000537752

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

FLURAZEPAM

Structure

Physicochemical Descriptors

Pharmacology

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